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Disease Mechanisms

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Disease Mechanisms

A man stands in a chemistry lab, with machinery on lab benches and reflections on glass partitions.

Using Click Chemistry to Drug ‘Undruggable’ Tumor Suppressors

November 7, 2025

Qinheng Zheng uses a daring approach to reveal new treatments for cancer

Cross-section of lung tissue shows 6 structures with bright pink outlines and hollow middles, amid purple, green, yellow, and blue dots like a starfield.

HMS Announces Blavatnik Institute Early Career Investigator Awards

November 6, 2025

10 projects receive basic and translational research funding

A pair of dramatically lit boxing gloves hanging on a wall

CTE Is Caused by More Than Head Trauma, New Study Suggests

October 30, 2025

Research reveals Alzheimer’s disease-like DNA damage, hints at immune involvement

Black drawings of sperm, two big and three small, on a tan background.

New Insights Into Harmful Mutations in Sperm

October 10, 2025

Researchers discover alterations are surprisingly common, identify genes involved

Artistic rendition of a brain with a mosaic-textured surface breaking apart in the front

Making Real Gains in the War on Alzheimer’s

September 19, 2025

Researchers hope new technologies, approaches usher in effective treatment

A chalk drawing of a human head with a brain inside

K. Lisa Yang Brain Body Center Launches at Harvard Medical School

September 17, 2025

Center will bring together scientists working to demystify brain-body communication

Eight circular views under a microscope of clusters of cells, ranging from sparse to dense

Addressing Twofold Lung Damage

September 9, 2025

Molecule could hold a key to repairing tissue harmed by infection, inflammation

A drawing of a computer with red blood cells displayed on the screen

New AI Tool Pinpoints Genes, Drug Combos To Restore Health in Diseased Cells

September 9, 2025

New model could optimize drug discovery

A wide angle photo of the newly named Veritas Science Center (VSC) building.

New Research Building Renamed as Veritas Science Center

September 3, 2025

Underscores Harvard Medical School’s commitment to research and discovery

A ball-like structure under a microscope. One side is mostly green and the other mostly magenta.

Seeding Solutions for Bipolar Disorder

August 25, 2025

11 new “outside-the-box” projects seek to illuminate causes, innovative treatments

White clouds on a blue sky

Breathing Low-Oxygen Air Improves Parkinson’s Symptoms in Mice

August 15, 2025

Evidence that hypoxia can prevent or reverse progression suggests new way to address disease

One pair of boxes shows fewer green amyloid clusters on the left and more on the right. Another pair of boxes shows a dim arc of purple and red tau on the left and a brighter arc on the right.

Could Lithium Explain — and Treat — Alzheimer’s Disease?

August 6, 2025

Study: Lithium loss ignites Alzheimer’s, but lithium compound can reverse disease in mice

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