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Disease Mechanisms

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Disease Mechanisms

Black drawings of sperm, two big and three small, on a tan background.

New Insights Into Harmful Mutations in Sperm

October 10, 2025

Researchers discover alterations are surprisingly common, identify genes involved

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Making Real Gains in the War on Alzheimer’s

September 19, 2025

Researchers hope new technologies, approaches usher in effective treatment

A chalk drawing of a human head with a brain inside

K. Lisa Yang Brain Body Center Launches at Harvard Medical School

September 17, 2025

Center will bring together scientists working to demystify brain-body communication

A drawing of a computer with red blood cells displayed on the screen

New AI Tool Pinpoints Genes, Drug Combos To Restore Health in Diseased Cells

September 9, 2025

New model could optimize drug discovery

A wide angle photo of the newly named Veritas Science Center (VSC) building.

New Research Building Renamed as Veritas Science Center

September 3, 2025

Underscores Harvard Medical School’s commitment to research and discovery

White clouds on a blue sky

Breathing Low-Oxygen Air Improves Parkinson’s Symptoms in Mice

August 15, 2025

Evidence that hypoxia can prevent or reverse progression suggests new way to address disease

One pair of boxes shows fewer green amyloid clusters on the left and more on the right. Another pair of boxes shows a dim arc of purple and red tau on the left and a brighter arc on the right.

Could Lithium Explain — and Treat — Alzheimer’s Disease?

August 6, 2025

Study: Lithium loss ignites Alzheimer’s, but lithium compound can reverse disease in mice

Closeup microscopy image of the HIV virus

2025 Warren Alpert Prize Honors Scientists Whose Discoveries Culminated in Novel HIV Treatment

June 19, 2025

Twice-a-year injection with lenacapavir can prevent HIV infection

A woman with long, straight hair and glasses sits at a round wooden table in a modern, sunlit building with large windows. She is wearing a black blazer and smiling confidently with arms crossed.

Virology Lab Probes the Dark Matter of Viral Genomes

June 12, 2025

Shira Weingarten-Gabbay finds proteins that help immune system ward off viruses

Top row: Untreated stem cells contain a protein (orange) marking its ability to mature into many different kinds of cells. Bottom row: Stem cells given a cocktail of transcription factors to coax them to become microglia-like cells express an array of proteins characteristic of human microglia. Images: Wyss Institute

Improving Creation of Microglia in a Dish for Brain Research

June 10, 2025

More efficient and authentic cell creation enables immune studies, drug development

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Awards & Recognitions: April/May 2025

June 9, 2025

Honors received by HMS faculty, postdocs, staff, and students

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Fish With Legs and Sea Slug Thieves: Lessons From Unusual Organisms

June 2, 2025

Corey Allard studies the extremes and exceptions to uncover fundamental biological principles

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