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Clinical Research

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Clinical Research

Clusters of purple circles on a white background

Exploring CRISPR Technology To Enhance Cancer Immunotherapy

September 25, 2025

Tool identifies gene edits that boost CAR T-cell therapy effectiveness in mice

Overhead view of an empty hospital bed with blue sheets, surrounded by privacy screens, with an IV stand on one side and a small table with supplies on the other.

Deaths Rose in Emergency Rooms After Hospitals Were Acquired by Private Equity Firms

September 22, 2025

Staffing, salary cuts offer likely explanation for increase compared to non-private-equity hospitals

Artistic rendition of a brain with a mosaic-textured surface breaking apart in the front

Making Real Gains in the War on Alzheimer’s

September 19, 2025

Researchers hope new technologies, approaches usher in effective treatment

Kricket and Jonathan Seidman and industry colleague Robert McDowell share the story of the journey that led to mavacamten

The First Precision Medicine for a Genetic Heart Disease

September 11, 2025

Discoveries in the Seidman Lab gave way to a novel treatment for hypertrophic cardiomyopathy

The First Precision Medicine for a Genetic Heart Disease

September 11, 2025
Discoveries in the Seidman Lab gave way to a novel treatment for hypertrophic cardiomyopathy
One pair of boxes shows fewer green amyloid clusters on the left and more on the right. Another pair of boxes shows a dim arc of purple and red tau on the left and a brighter arc on the right.

Could Lithium Explain — and Treat — Alzheimer’s Disease?

August 6, 2025

Study: Lithium loss ignites Alzheimer’s, but lithium compound can reverse disease in mice

Close-up image of Mycobacterium tuberculosis bacterial colonies growing on a solid nutrient medium. The colonies appear rough, irregular, buff-colored, and bubbly, resembling small cauliflower-like clusters on a blue-gray background.

In Hard-To-Treat Form of Tuberculosis, Shorter, Gentler Therapy Shows Unequal Benefit

July 16, 2025

Study suggests treatment should be tailored for disease severity

A plastic model of the female reproductive system in the foreground, with a doctor from the shoulders down out of focus in the background reviewing ultrasound images

Could Migraine Drugs Help Treat Endometriosis?

March 28, 2025

Research in mice suggests headache medications may reduce symptoms of the gynecologic disorder

A hand in a protective glove, using a futuristic screen to look at a diagram

Open-Source AI Matches Top Proprietary LLM in Solving Tough Medical Cases

March 14, 2025

Greater competition between AI diagnostic tools should benefit patients and clinicians

In an operating room, three people in blue surgical gowns, masks, and head covers look through microscopes while performing surgery on a patient.

Stem Cell Therapy Repairs Cornea Damage Thought Irreversible

March 10, 2025

Regenerative medicine trial shows promise using patients’ own healthy corneas

Two scientists — one in a lab coat and one in a cardigan — collaborate at a whiteboard with chemical diagrams

Blavatnik Therapeutics Challenge Awards Fuel Translational Research

March 3, 2025

Awards aim to accelerate translation of discoveries made at Harvard Medical School into new…

Stuart Orkin, standing in a laboratory wearing a suit, looks into the camera with a slight smile

Creating the World’s First CRISPR Medicine, for Sickle Cell Disease

February 20, 2025

How a genetic insight paired with gene editing technology led to a life-changing new therapy

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