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structural biology

structural biology

A purple circular Nipah virus particle floats in a field of pink surrounded by brown VERO cells.

Scientists Uncover Structure of Critical Component in Deadly Nipah Virus

January 20, 2025

Findings could inform the design of treatments to combat infection

illustration of A. baumannii bacteria at the microscopic level look like a cluster of dimpled mini-marshmallows

Paving the Way for a New Class of Antibiotics

March 5, 2024

Flaws in superbugs’ armor could be exploited to combat antibiotic resistance

Illustration of a protein complex with a round-ish blue center section and two taller, thinner wing-like structures on the sides

Inside a Bacterial Defense System — and Its Defeat

January 11, 2024

Study reveals unexpected strategy in competition between bacteria and viruses

Three black-and-white microscope images of a protein with three segments, the third one curved like a tail

Researchers Reveal Structure of Unusual Hormone Receptor

April 27, 2023

Study provides foundation for design of drugs to treat heart disease, scar tissue buildup

Candid photo of a gray-haired man in glasses grinning in a chair while being interviewed

Christopher T. Walsh Dies

January 11, 2023

Biochemist revealed molecular basis of antibiotic resistance

Squares show the inflammasome from different angles. Some look like spoked wheels. Others look like sandwich cookies from the side.

Researchers Decipher Structure of Crucial Immune Molecule, Paving Way for Drug Design

November 28, 2022

Inflammasome is implicated in autoimmunity, heart disease, neurodegeneration, and more

microscope image of a ball-like cell with many protrusions

Study Reveals Detailed Structure of B-Cell Receptor

October 25, 2022

Findings can inform vaccines, treatments for COVID, cancers, and beyond

Fluorescent dye lights up actin strings in a cell in a rainbow of colors. The cell edge glows in a shape like a fried egg against a black backdrop.

A Solution That Holds Water

September 15, 2022

Researchers uncover why some drugs fail to suppress common protein

SARS-CoV-2 particle in gray with spikes studding surface in red, against a black background

Unwanted Stability

March 24, 2021

Sturdier spikes may explain SARS-CoV-2 variants’ faster spread

Magnified image of a spherical cell with many protrusions on its surface, colored blue-green

B Side

January 26, 2021

Sharp images of immune protein pair promise to guide drug design

Illustration shows a ring, side-on, with 9 columns in green, and other vertebrae-like studs in pink, blue and beige

Skeleton Key

October 30, 2019

Researchers reveal structures of skeletal components in hair-like cilia

An illustration of B-Raf's structure rotates in front of a cryo-EM field of the proteins

Caught in the Act

October 23, 2019

First snapshots of cancer protein B-Raf illuminate basic biology, drug design

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