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Harvard Medical School Researchers Win NIH Director’s New Innovator Awards

High-Risk, High-Reward Research program backs bold projects in biology

2 min read
Abstract illustration of glowing DNA strands and molecular structures in blue and pink.

Catalog of Mitochondria Across Tree of Life Unearths New Roles for the Cell’s Powerhouse

Survey also suggests new opportunities for treating parasitic infections

5 min read
Fluorescent microscopy shows three teardrop-shaped Giardia parasites, each with two nuclear structures like eyes and scattered with green dots indicating mitochondria.

‘Molecular Movie’ Fills in Blanks of How Non-Enveloped Viruses Infect Cells

Cryo-ET of rotavirus answers decades-old virology question, could inform drug delivery techniques

3 min read
Cryo-electron microscopy views of a round rotavirus enclosed in a membrane-bound compartment. White arrows indicate where viral proteins have created an opening in the membrane.

Possible New Target for Sickle Cell Disease and Beta Thalassemia Treatment

Researchers identify additional gene controlling production of fetal hemoglobin

2 min read
About two dozen cells are seen under a microscope. Part of each cell is stained purple like a half-moon.

ARPA-H Award Seeks To Advance Production of Genetic Medicines

New tools will make personalized RNA medicines more accessible

2 min read
A pipette releases a drop of liquid into a lab dish sitting on a backlit display showing colorful DNA sequencing bands.

Rare Inherited Genetic Mutation Is One of Strongest Indicators Yet for Lung Cancer Risk

Influence of EGFR variant could expand screening guidelines

4 min read
A radiologist in a green shirt looks at a screen showing four images of CT lung scans; a white CT scanner appears blurred in the background.

Allon Klein Named 2026 Schmidt Science Polymath

$2.5 million award supports ambitious leaps in new directions

2 min read
Portrait photo of Allon Klein in his lab.

New Mechanism of Antiviral Immunity Discovered

Study shows how cells target viruses in first hour after infection

4 min read
Glowing green blobs of DNA emerging from the nucleus of a human cell in a lab dish.

Newly Approved Pancreatic Cancer Treatment Seen as ‘Critical First Step’ Toward Transforming Care

KRAS inhibitors are raising hopes, says clinical trial investigator Brian Wolpin

5 min read
Alt text: Portrait photo of Brian Wolpin in a white coat.
Harvard Medicine magazineResearch

How Cancer Cells Decide Their Fate

In studying a key cancer protein, Galit Lahav is revealing the importance of rhythm and timing in biology

5 min read
Smiling woman standing with folded arms in a laboratory surrounded by glassware, scientific supplies, and equipment.

New Gene-Editing Method, ‘Prime Assembly,’ Corrects Multiple Mutations at Once

Approach builds on prime editing, advances journey toward universal gene therapies

2 min read
Illustration of a segment of a DNA double helix with one half in pink and the other in teal. The middle portion of the pink half is separated from the main molecule.

Researchers Create Molecular Map of Hypertrophic Cardiomyopathy

Findings from nearly 1 million heart cells could inform more precise treatments

3 min read
Reconstructed microscope view of cardiac cells labeled in blue and green, from a person with hypertrophic cardiomyopathy. One heart cell is outlined in orange and has many dots inside.