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Newly Approved Pancreatic Cancer Treatment Seen as ‘Critical First Step’ Toward Transforming Care

KRAS inhibitors are raising hopes, says clinical trial investigator Brian Wolpin

5 min read
Alt text: Portrait photo of Brian Wolpin in a white coat.
Harvard Medicine magazineResearch

How Cancer Cells Decide Their Fate

In studying a key cancer protein, Galit Lahav is revealing the importance of rhythm and timing in biology

5 min read
Smiling woman standing with folded arms in a laboratory surrounded by glassware, scientific supplies, and equipment.

New Gene-Editing Method, ‘Prime Assembly,’ Corrects Multiple Mutations at Once

Approach builds on prime editing, advances journey toward universal gene therapies

2 min read
Illustration of a segment of a DNA double helix with one half in pink and the other in teal. The middle portion of the pink half is separated from the main molecule.

Researchers Create Molecular Map of Hypertrophic Cardiomyopathy

Findings from nearly 1 million heart cells could inform more precise treatments

3 min read
Reconstructed microscope view of cardiac cells labeled in blue and green, from a person with hypertrophic cardiomyopathy. One heart cell is outlined in orange and has many dots inside.

Pioneer in Cancer Vaccines Sees Promise In — and Beyond — Melanoma Trial

“This is not a time that we should be pulling back,” says Catherine Wu

4 min read
Portrait photo of Catherine Wu

Targeting CDK2 Could Boost Cancer Immunotherapy Response

Findings in mice suggest blocking protein can reduce resistance to immune checkpoint inhibitors

3 min read
A health care professional administers a medication in a syringe connected to a hanging IV bag beside a seated patient.

Discovery Fills a Gap in Understanding, Diagnosing Primary Ciliary Dyskinesia

Study finds mutations in two genes that disrupt ability of cilia to clear mucus in lungs

3 min read
Two collections of about 10 fluorescently labeled cilia under a microscope look like long parallel strands with a short green cuff toward the bottom end.

Research Provides Clues to Spleen’s Role in Coronary Artery Disease

Genetic variants may drive visible changes in the spleen that contribute to heart disease

3 min read
A grid of four abdominal MRI scans, with the spleen outlined in blue or marked by numerous dots added by AI.

Scientists Reveal How the Monkeypox Virus Replicates

Findings deepen understanding of what drives infection, could inform new therapies

4 min read
Teal-colored, speckled speres in a textured brown background.

Engineered Bacteria Could Speed Rock Weathering To Combat Climate Change

Microbes help break down rocks, capture carbon dioxide

3 min read
Photo of four clear tanks on a lab bench, each containing green sand and murky water.

Harvard, Yale Researchers Awarded $46 Million Grant To Study Autism, Brain Development

Leads include stem cell biologist Paola Arlotta, biomedical AI researcher Marinka Zitnik

3 min read
A photo of a petri dish with nine brain organoids, which look like small, white balls, resting on the bottom.

Patient Who Received Pig Kidney Becomes First To Progress to Human Kidney Transplant

Study shows xenotransplantation can serve as a bridge for patients with end-stage kidney disease

2 min read
A patient in a hospital bed talks to two surgeons in doctors’ coats and masks.