SARS-CoV-2 particle in gray with spikes studding surface in red, against a black background

Unwanted Stability

Sturdier spikes may explain SARS-CoV-2 variants’ faster spread

Image of young man against black background with illustrations of molecule and flask

A Screen Door Opens

Largest-ever virtual screen finds compounds that could combat SARS-CoV-2

Magnified image of a spherical cell with many protrusions on its surface, colored blue-green

B Side

Sharp images of immune protein pair promise to guide drug design

Illustration of a DNA double helix looped back on itself. Two antibodies embedded in the DNA have bound to a SARS-CoV-2 particle.

New Virus, New Test

Researchers explore DNA nanoswitches for diagnosing COVID-19

Black and white microscope image shows dozens or hundreds of tube-like projections aligned in different directions

Intestinal Insight

Bile component appears to help lower high blood sugar after bariatric surgery

3-D depiction of the gasdermin pore

Smothering the Fire

Drug prevents runaway inflammatory cell death in mice, could relate to COVID-19

professor in sweater with cat on armchair

Scientists@Home

As most labs shift to remote work, HMS researchers find ways to keep the science going

Animation shows a chemical compound binding to a protein like a puzzle piece

A Galaxy of Drug Candidates

New software screens billions of compounds in search of new medicines—including for COVID-19

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