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Animation shows a chemical compound binding to a protein like a puzzle piece

A Galaxy of Drug Candidates

New software screens billions of compounds in search of new medicines—including for COVID-19

cryoem

Inner Workings

Harvard Cryo-EM Center helps researchers transform biomedical research, one structure at a time

microscopy image of herpes simplex virus

Herpes' Achilles' Heel

Experiments pinpoint weak spot that can make the virus susceptible to gene editing

Illustration shows a ring, side-on, with 9 columns in green, and other vertebrae-like studs in pink, blue and beige

Skeleton Key

Researchers reveal structures of skeletal components in hair-like cilia

An illustration of B-Raf's structure rotates in front of a cryo-EM field of the proteins

Caught in the Act

First snapshots of cancer protein B-Raf illuminate basic biology, drug design

Images of Chuck Norris, the Buffybot and Robocop alongside researcher Lizz Thrall

Action Heroes of DNA Repair

From “Robocop” to the “Buffybot,” custom-built microscopes illuminate cancer, gene editing

gut microbiome

Microbial Fingerprinting

In a first, scientists map the genetic diversity of microbes residing in the human gut and mouth

18 square microscopy images of curly protein in different orientations

Swell Snapshots

First sharp images reveal structure of key inflammatory protein