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Disease Mechanisms

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Disease Mechanisms

Artwork depicts two silhouetted heads facing away from each other. One has a dark cloud with scrambled lines in it where the brain would be, representing low mood. The other head has a shining sun.

Toward More Personalized Depression Treatments

November 1, 2024

How two HMS scientists hope to speed journey from diagnosis to recovery

Photo of a young girl lying on blankets wearing a hospital gown featuring cartoon characters.

Genetic Detectives Diagnose Child With Ultra-Rare Disorder

October 31, 2024

Work highlights need to examine noncoding parts of genome in rare diseases

HMS shield

Awards & Recognitions: October 2024

October 28, 2024

Honors received by HMS faculty, postdocs, staff, and students

Microscope image of fluorescent human cells

HMS Researcher Wins NIH Director’s Transformative Research Award

October 24, 2024

Stem cell and regenerative biologist Ryan Flynn will receive funding for glycoRNA research

Side-by-side images show different patterns under a microscope. One is more condensed and crinkled in rows, while the other has flatter whorls like the surface of a brain.

How Genetics and Physics Interact To Form the Gut

October 22, 2024

Studies illuminate connection between biology, physical forces in embryonic development

Illustration of a human brain with lighted signaling pathways

Rapid Release of Dopamine Not Needed for Initiating Movement, Study Reveals

October 16, 2024

Research in mice explains why widely used Parkinson’s drug works for some symptoms but not others

Gary Ruvkun with daughter Victoria Ruvkun (left), dog Barnaby, and wife Natasha Staller the morning of the announcement at their home in Newton.

Harvard Medical School Scientist Gary Ruvkun Receives Nobel Prize for Discovery of microRNA

October 7, 2024

Ruvkun shares award for elucidating fundamental principle of gene activity regulation

Gordon Freeman and Arlene Sharpe with the Hamburg Award on a dark background

Gordon Freeman and Arlene Sharpe Receive Hamburg Award

September 26, 2024

National Academy of Medicine award recognizes contributions to cancer immunotherapy

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Researchers Harness AI to Repurpose Existing Drugs for Treatment of Rare Diseases

September 25, 2024

New AI model identifies drug candidates from existing medicines for thousands of rare diseases

A white football helmet rests on a grass field in a stadium

Study of Former NFL Players Finds 1 in 3 Believes They Have CTE

September 24, 2024

Players also report higher rates of suicidality, treatable conditions that mimic CTE

a blobby cluster of cancer cells glows blue with green edges under a microscope

Overriding Tumors’ Genetic Changes to Fight Cancer

September 19, 2024

Study illuminates immune-evading mechanism, suggests how to turn the tables

Portrait photo of Joel Habener

Harvard Medical School Researcher Wins 2024 Lasker Award for Work That Led to GLP-1 Therapies

September 19, 2024

Joel Habener, fellow scientists honored for discoveries paving the way to GLP-1 based treatments

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