Researchers have discovered a defective gene that’s responsible for more than one-quarter of cases of inherited dilated cardiomyopathy, a serious heart muscle disease that often leads to heart failure by middle age. Jonathan Seidman, the Henrietta B. and Frederick H. Bugher Foundation Professor of Genetics at HMS, and Christine Seidman, the Thomas W. Smith Professor of Medicine and Genetics at HMS and Brigham and Women’s Hospital, are co-authors of the study.

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