Dr. Emil Frei III, an oncologist whose trailblazing use of combination chemotherapy — in which anticancer drugs are administered simultaneously rather than singly — helped make certain cancers curable for the first time, died on Tuesday at his home in Oak Park, Ill. He was 89. Frei was the emeritus director and emeritus physician- in-chief of the Dana-Farber Cancer Institute. He was also the Richard and Susan Smith distinguished professor of medicine emeritus at HMS.
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