If all goes according to plan, 1,000 older people who have no symptoms of Alzheimer’s disease, but who have an abnormal protein in their brains believed to be a hallmark of the illness, will be selected to test whether drugs can hold off the disease in a first of its kind study to be led by Boston scientists. Reisa Sperling, HMS professor of neurology at Brigham and Women’s Hospital, is the lead researcher.

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