Eight Harvard Medical School affiliated researchers are among the recipients of eighty-five grants awarded to scientists proposing highly innovative approaches to major contemporary challenges in biomedical research, under the High Risk-High Reward program supported by the National Institutes of Health’s Common Fund. Awardees from previous years have made scientific leaps, established new scientific paradigms, and, in some cases, revolutionized entire fields.
"Supporting innovative investigators with the potential to transform scientific fields is a critical element of our mission,”’ said NIH Director Francis Collins. "This program allows researchers to propose highly creative research projects across a broad range of biomedical and behavioral research areas that involve inherent risk but have the potential to lead to dramatic breakthroughs."
NIH Pioneer, New Innovator, Transformative Research, and Early Independence awards encourage creative thinkers to pursue exciting and innovative ideas in biomedical and behavioral research.
NIH Director's Pioneer Award
Chenghua Gu,
HMS associate professor of neurobiology
New tools for understanding the blood brain barrier
NIH Director's New Innovator Award
Mark Andermann, HMS assistant professor of medicine at Beth Israel Deaconess Medical Center
Multiphoton imaging of thoughts of food during natural and induced hunger states
Robert Anthony, HMS assistant professor of medicine at Massachusetts General Hospital
Glycoengineering In Vivo
Cigall Kadoch, HMS assistant professor of pediatrics and pediatric oncology at Dana-Farber Cancer Institute
Reversing Oncogenic BAF Complex Structure & Function: New Therapeutic Approaches
NIH Director's Early Independence Award
John Hanna, HMS instructor in pathology at Brigham and Women's Hospital
New Ubiquitin-Proteasome System Components that Protect against Proteotoxicity
Duncan Maru, HMS instructor in medicine at Brigham and Women's Hospital
Integrating Pediatric Care Delivery in Rural Healthcare Systems
Yakeel Quiroz, HMS clinical fellow in psychology at Massachusetts General Hospital
Memory network dysfunction as an early marker of preclinical Alzheimers Disease
NIH Director's Transformative Research Award
Alexander Gimelbrant, HMS assistant professor of genetics at Dana-Farber Cancer Institute
Mechanism and function of autosomal analog of X inactivation
