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Scientists Create First Blueprint of Entire Mouse Gut

Map of genes and cells by location reveals organ’s stunning resilience

3 min read
A cross-section of intestinal lining appears like irregular ovals with complex cell structures, shown in brown with green rings and occasional purple cells

How Cells Habituate

Surprising new study shows single-cell organisms exhibit this simple form of learning

2 min read
Single-cell organism on a microscope slide

Second Gene Therapy Shows Promise for Syndrome Involving Blindness, Deafness

Method restored hearing, showed signs of improved vision in animals and organoids

2 min read
Cells in a row under a microscope have wider bases and long tails bending slightly to the left like reeds in a breeze. Each cell is fluorescently tagged purple with a dot of green about halfway up.

How Even One Faulty Copy of the BRCA1 Gene Can Fuel Breast Cancer

Research adds a new twist to prevailing two-hit model, offering new insight for prevention

4 min read
A vial of blood labeled BRCA genetic test

How Cancer Immunotherapy Fuels Heart Inflammation in Some Patients

Myocarditis appears to be triggered by immune response different from the one aimed at the tumor

5 min read
Illustration of a heart shaded red and blue against a dark background, with white lines and nodes overlaid on it like it is being mapped

Ancient DNA Challenges Stories Told About Pompeii Victims

Genetic data contradict, enrich interpretations of archaeological site

2 min read
Plaster casts of two figures entangled on a tile floor

Breast Cancer Increasing Among Younger Women, Latest Data Show

Harvard Medical School physician-scientist shares insights

5 min read
Microscopic image of breast cancer cells with purple, pink, and red shapes

Toward More Personalized Depression Treatments

How two HMS scientists hope to speed journey from diagnosis to recovery

4 min read
Artwork depicts two silhouetted heads facing away from each other. One has a dark cloud with scrambled lines in it where the brain would be, representing low mood. The other head has a shining sun.

Genetic Detectives Diagnose Child With Ultra-Rare Disorder

Work highlights need to examine noncoding parts of genome in rare diseases

2 min read
Photo of a young girl lying on blankets wearing a hospital gown featuring cartoon characters.

HMS Researcher Wins NIH Director’s Transformative Research Award

Stem cell and regenerative biologist Ryan Flynn will receive funding for glycoRNA research

1 min read
Microscope image of fluorescent human cells

How Genetics and Physics Interact To Form the Gut

Studies illuminate connection between biology, physical forces in embryonic development

4 min read
Side-by-side images show different patterns under a microscope. One is more condensed and crinkled in rows, while the other has flatter whorls like the surface of a brain.
Harvard Medicine magazineResearch

Did AI Solve the Protein-Folding Problem?

Now that AlphaFold has tackled biology’s greatest challenge, scientists can turn to even bigger questions

12 min read
a tangled mass of red and pink tubes illustrating oxyhemoblobin