Understanding how drugs are developed matters crucially because the government and companies pour billions of dollars into the endeavor. Jon Clardy, Hsien Wu and Daisy Yen Wu Professor of Biological Chemistry and Molecular Pharmacology; Daniel A. Haber, Kurt J. Isselbacher/Peter D. Schwartz Professor of Oncology at Massachusetts General Hospital; and Thomas Bernhardt, associate professor of microbiology and immunobiology, are quoted.