Local researchers could transform treatment for conditions ranging from Alzheimer’s to depression, heart disease to cancer. Gordon Freeman (Dana-Farber), Pier Paolo Pandolfi (Beth Israel Deaconess), Alvaro Pascual-Leone (Beth Israel Deaconess), Reisa Sperling (Brigham and Women’s), Elizabeth Hohmann (Mass General), Paolo Cassano (Mass General), Michael Rohan (McLean Hospital), Steven Russell (Mass General), Raymond Chung (Mass General), Marc Kaufman (McLean Hospital) and Stuart Orkin (Dana-Farber) are quoted.