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cryo-em

cryo-em

Squares show the inflammasome from different angles. Some look like spoked wheels. Others look like sandwich cookies from the side.

Researchers Decipher Structure of Crucial Immune Molecule, Paving Way for Drug Design

November 28, 2022

Inflammasome is implicated in autoimmunity, heart disease, neurodegeneration, and more

Close-up, head-on shot of a mosquito perched on pale human skin

Scent of a Human

May 3, 2022

Researcher probes mysteries of smell through disease-carrying insects

Multiple rectangular compartments filled with large, multi-colored pills

Combating Antibiotic Resistance

November 2, 2021

As bacterial infections impervious to drugs rise, so does the need to develop better antibiotics

SARS-CoV-2 particle in gray with spikes studding surface in red, against a black background

Unwanted Stability

March 24, 2021

Sturdier spikes may explain SARS-CoV-2 variants’ faster spread

Magnified image of a spherical cell with many protrusions on its surface, colored blue-green

B Side

January 26, 2021

Sharp images of immune protein pair promise to guide drug design

cryoem

Inner Workings

February 10, 2020

Harvard Cryo-EM Center helps researchers transform biomedical research, one structure at a time

Illustration shows a ring, side-on, with 9 columns in green, and other vertebrae-like studs in pink, blue and beige

Skeleton Key

October 30, 2019

Researchers reveal structures of skeletal components in hair-like cilia

An illustration of B-Raf's structure rotates in front of a cryo-EM field of the proteins

Caught in the Act

October 23, 2019

First snapshots of cancer protein B-Raf illuminate basic biology, drug design

18 square microscopy images of curly protein in different orientations

Swell Snapshots

June 20, 2019

First sharp images reveal structure of key inflammatory protein

A New Era

A New Era

May 31, 2018

Inaugural symposium lauds Harvard’s new cryo-EM center for structural biology

3-D depiction of the gasdermin pore

Guardians of the Ring

April 30, 2018

Researchers reveal structure of protein involved in inflammatory diseases

 Alan Brown

BCMP Welcomes Alan Brown

February 27, 2018

Structural biologist eager to study the mysterious cilium

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