11 05, 2019 30 (5) 847-849
Vol. 30, Issue 5, Medline Page 847-849
The DAPA-HF Trial: A Momentous Victory in the War against Heart Failure.
In a randomized trial of patients with heart failure and reduced ejection fraction, the SGLT2 inhibitor dapagliflozin markedly reduced mortality and worsening heart failure (McMurray et al., 2019). Remarkably, these benefits seemed to be similar in people with and without diabetes. These data usher in a new paradigm in the treatment of heart failure.