Sep 09, 2019 50 (5) 530-532
Vol. 50, Issue 5, Medline Page 530-532
Un-phased: Lipid Droplets Modulate the Bioavailability of Antibiotics.
In a paper recently published in Science (Greenwood et al., 2019), Greenwood and colleagues now describe a fascinating example of how partitioning of a small lipophilic molecule into a phase-separated cellular constituent, the lipid droplet (LD), contributes to its antibacterial action against Mycobacterium tuberculosis.