Paper Chase

Paper Chase is a research database designed to offer abstracts of research articles published in journals that have a highly rated impact factor as determined by ISI Impact Factor and PageRank. Abstracts are organized by date, with the most recently published papers listed first.

Neuron
Feb 06, 2019 101 (3) 351-352
Vol. 101, Issue 3, Medline Page 351-352

Effects of Species-Specific Genetics on Alzheimer's Mouse Models.

Authors: Hyman B, Tanzi RE
Abstract:
In this issue of Neuron, Neuner et al. (2019) report the generation of Alzheimer's disease (AD) transgenic mouse models on a panel of 28 background strains, showing marked background-dependent phenotypic variability. These findings imply that analogous variation in human AD phenotypes may be due, at least in part, to subtle effects of genetic background.