Feb 05, 2019 29 (2) 243-245
Vol. 29, Issue 2, Medline Page 243-245
Regulatory T Cells under the Mercy of Mitochondria.
Mitochondria, the powerhouse of the cell, known for producing energy through oxidative phosphorylation and the Krebs cycle, continue gaining notoriety for roles beyond bioenergetics. Recently in Nature, Weinberg et al. (2019) reported that mitochondrial complex III is indispensable for suppressive function of regulatory T cells, thus highlighting the importance of mitochondria in immune tolerance.