Paper Chase is a research database designed to offer abstracts of research articles published in journals that have a highly rated impact factor as determined by ISI Impact Factor and PageRank. Abstracts are organized by date, with the most recently published papers listed first. 

Paper Chase

81.

Genome-scale deletion screening of human long non-coding RNAs using a paired-guide RNA CRISPR-Cas9 library.

Nat. Biotechnol.
Zhu S, Li W, Liu J, Chen CH, Liao Q, Xu P, Xu H, Xiao T, Cao Z, Peng J, Yuan P, Brown M, Liu XS, Wei W.
| 10 31, 2016
82.

Drug sensitivity of single cancer cells is predicted by changes in mass accumulation rate.

Nat. Biotechnol.
Stevens MM, Maire CL, Chou N, Murakami MA, Knoff DS, Kikuchi Y, Kimmerling RJ, Liu H, Haidar S, Calistri NL, Cermak N, Olcum S, Cordero NA, Idbaih A, Wen PY, Weinstock DM, Ligon KL, Manalis SR.
| 10 10, 2016
83.

Suppression by TFR cells leads to durable and selective inhibition of B cell effector function.

Nat. Immunol.
Sage PT, Ron-Harel N, Juneja VR, Sen DR, Maleri S, Sungnak W, Kuchroo VK, Haining WN, Chevrier N, Haigis M, Sharpe AH.
| 10 03, 2016
84.

Modeling of RNA-seq fragment sequence bias reduces systematic errors in transcript abundance estimation.

Nat. Biotechnol.
Love MI, Hogenesch JB, Irizarry RA.
| 09 26, 2016
85.

Structural basis for dynamic regulation of the human 26S proteasome.

Proc. Natl. Acad. Sci. U.S.A.
Chen S, Wu J, Lu Y, Ma YB, Lee BH, Yu Z, Ouyang Q, Finley DJ, Kirschner MW, Mao Y.
| Nov 15, 2016
86.

FOXA1 overexpression mediates endocrine resistance by altering the ER transcriptome and IL-8 expression in ER-positive breast cancer.

Proc. Natl. Acad. Sci. U.S.A.
Fu X, Jeselsohn R, Pereira R, Hollingsworth EF, Creighton CJ, Li F, Shea M, Nardone A, De Angelis C, Heiser LM, Anur P, Wang N, Grasso CS, Spellman PT, Griffith OL, Tsimelzon A, Gutierrez C, Huang S, Edwards DP, Trivedi MV, Rimawi MF, Lopez-Terrada D, Hilsenbeck SG, Gray JW, Brown M, Osborne CK, Schiff R.
| Oct 25, 2016
87.

The epigenetic landscape of T cell exhaustion.

Science.
Sen DR, Kaminski J, Barnitz RA, Kurachi M, Gerdemann U, Yates KB, Tsao HW, Godec J, LaFleur MW, Brown FD, Tonnerre P, Chung RT, Tully DC, Allen TM, Frahm N, Lauer GM, Wherry EJ, Yosef N, Haining WN.
| Dec 02, 2016
88.

Epigenetic stability of exhausted T cells limits durability of reinvigoration by PD-1 blockade.

Science.
Pauken KE, Sammons MA, Odorizzi PM, Manne S, Godec J, Khan O, Drake AM, Chen Z, Sen DR, Kurachi M, Barnitz RA, Bartman C, Bengsch B, Huang AC, Schenkel JM, Vahedi G, Haining WN, Berger SL, Wherry EJ.
| Dec 02, 2016
89.

Targeting mutant p53 through the mevalonate pathway.

Nat. Cell Biol.
Freed-Pastor W, Prives C.
| Oct 27, 2016
90.

The genomic landscape of schwannoma.

Nat. Genet.
Agnihotri S, Jalali S, Wilson MR, Danesh A, Li M, Klironomos G, Krieger JR, Mansouri A, Khan O, Mamatjan Y, Landon-Brace N, Tung T, Dowar M, Li T, Bruce JP, Burrell KE, Tonge PD, Alamsahebpour A, Krischek B, Agarwalla PK, Bi WL, Dunn IF, Beroukhim R, Fehlings MG, Bril V, Pagnotta SM, Iavarone A, Pugh TJ, Aldape KD, Zadeh G.
| 10 10, 2016
91.

Progress towards generation of human haematopoietic stem cells.

Nat. Cell Biol.
Wahlster L, Daley GQ.
| 10 10, 2016
92.

Protein 4.1R Influences Myogenin Protein Stability and Skeletal Muscle Differentiation.

J. Biol. Chem.
Huang SC, Zhou A, Nguyen DT, Zhang HS, Benz EJ.
| Dec 02, 2016
93.

Phenotypic Characterization of a Comprehensive Set of MAPK1/ERK2 Missense Mutants.

Cell Rep.
Brenan L, Andreev A, Cohen O, Pantel S, Kamburov A, Cacchiarelli D, Persky NS, Zhu C, Bagul M, Goetz EM, Burgin AB, Garraway LA, Getz G, Mikkelsen TS, Piccioni F, Root DE, Johannessen CM.
| Oct 18, 2016
94.

Pre-T Cell Receptors (Pre-TCRs) Leverage Vβ Complementarity Determining Regions (CDRs) and Hydrophobic Patch in Mechanosensing Thymic Self-ligands.

J. Biol. Chem.
Das DK, Mallis RJ, Duke-Cohan JS, Hussey RE, Tetteh PW, Hilton M, Wagner G, Lang MJ, Reinherz EL.
| Dec 02, 2016
95.

Environment Dictates Dependence on Mitochondrial Complex I for NAD+ and Aspartate Production and Determines Cancer Cell Sensitivity to Metformin.

Cell Metab.
Gui DY, Sullivan LB, Luengo A, Hosios AM, Bush LN, Gitego N, Davidson SM, Freinkman E, Thomas CJ, Vander Heiden MG.
| Nov 08, 2016
96.

Divide and Conquer to Treat Lung Cancer.

N. Engl. J. Med.
Johnson BE.
| 11 10, 2016
97.

Nivolumab for Recurrent Squamous-Cell Carcinoma of the Head and Neck.

N. Engl. J. Med.
Ferris RL, Blumenschein G, Fayette J, Guigay J, Colevas AD, Licitra L, Harrington K, Kasper S, Vokes EE, Even C, Worden F, Saba NF, Iglesias Docampo LC, Haddad R, Rordorf T, Kiyota N, Tahara M, Monga M, Lynch M, Geese WJ, Kopit J, Shaw JW, Gillison ML.
| Nov 10, 2016
98.

Niraparib Maintenance Therapy in Platinum-Sensitive, Recurrent Ovarian Cancer.

N. Engl. J. Med.
Mirza MR, Monk BJ, Herrstedt J, Oza AM, Mahner S, Redondo A, Fabbro M, Ledermann JA, Lorusso D, Vergote I, Ben-Baruch NE, Marth C, Mądry R, Christensen RD, Berek JS, Dørum A, Tinker AV, du Bois A, González-Martín A, Follana P, Benigno B, Rosenberg P, Gilbert L, Rimel BJ, Buscema J, Balser JP, Agarwal S, Matulonis UA, Lund B.
| 12 01, 2016
99.

Prolonged Survival in Stage III Melanoma with Ipilimumab Adjuvant Therapy.

N. Engl. J. Med.
Eggermont AM, Chiarion-Sileni V, Grob JJ, Dummer R, Wolchok JD, Schmidt H, Hamid O, Robert C, Ascierto PA, Richards JM, Lebbé C, Ferraresi V, Smylie M, Weber JS, Maio M, Bastholt L, Mortier L, Thomas L, Tahir S, Hauschild A, Hassel JC, Hodi FS, Taitt C, de Pril V, de Schaetzen G, Suciu S, Testori A.
| Nov 10, 2016
100.

Daratumumab, Lenalidomide, and Dexamethasone for Multiple Myeloma.

N. Engl. J. Med.
Dimopoulos MA, Oriol A, Nahi H, San-Miguel J, Bahlis NJ, Usmani SZ, Rabin N, Orlowski RZ, Komarnicki M, Suzuki K, Plesner T, Yoon SS, Ben Yehuda D, Richardson PG, Goldschmidt H, Reece D, Lisby S, Khokhar NZ, O'Rourke L, Chiu C, Qin X, Guckert M, Ahmadi T, Moreau P, Cochrane T.
| Oct 06, 2016