Paper Chase is a research database designed to offer abstracts of research articles published in journals that have a highly rated impact factor as determined by ISI Impact Factor and PageRank. Abstracts are organized by date, with the most recently published papers listed first. 

Paper Chase

61.

ENL links histone acetylation to oncogenic gene expression in acute myeloid leukaemia.

Nature.
Wan L, Wen H, Li Y, Lyu J, Xi Y, Hoshii T, Joseph JK, Wang X, Loh YE, Erb MA, Souza AL, Bradner JE, Shen L, Li W, Li H, Allis CD, Armstrong SA, Shi X.
| Mar 09, 2017
62.

Transcription control by the ENL YEATS domain in acute leukaemia.

Nature.
Erb MA, Scott TG, Li BE, Xie H, Paulk J, Seo HS, Souza A, Roberts JM, Dastjerdi S, Buckley DL, Sanjana NE, Shalem O, Nabet B, Zeid R, Offei-Addo NK, Dhe-Paganon S, Zhang F, Orkin SH, Winter GE, Bradner JE.
| Mar 09, 2017
63.

TIRR regulates 53BP1 by masking its histone methyl-lysine binding function.

Nature.
Drané P, Brault ME, Cui G, Meghani K, Chaubey S, Detappe A, Parnandi N, He Y, Zheng XF, Botuyan MV, Kalousi A, Yewdell WT, Münch C, Harper JW, Chaudhuri J, Soutoglou E, Mer G, Chowdhury D.
| Mar 09, 2017
64.

Doubling Down on Mutant RAS Can MEK or Break Leukemia.

Cell.
Tothova Z, Ebert BL.
| Feb 23, 2017
65.

Mass Spectrometry Profiling of HLA-Associated Peptidomes in Mono-allelic Cells Enables More Accurate Epitope Prediction.

Immunity.
Abelin JG, Keskin DB, Sarkizova S, Hartigan CR, Zhang W, Sidney J, Stevens J, Lane W, Zhang GL, Eisenhaure TM, Clauser KR, Hacohen N, Rooney MS, Carr SA, Wu CJ.
| Feb 21, 2017
66.

Loss of PTEN Is Associated with Resistance to Anti-PD-1 Checkpoint Blockade Therapy in Metastatic Uterine Leiomyosarcoma.

Immunity.
George S, Miao D, Demetri GD, Adeegbe D, Rodig SJ, Shukla S, Lipschitz M, Amin-Mansour A, Raut CP, Carter SL, Hammerman P, Freeman GJ, Wu CJ, Ott PA, Wong KK, Van Allen EM.
| Feb 21, 2017
67.

Niraparib in Recurrent Ovarian Cancer.

N. Engl. J. Med.
Mirza MR, Matulonis UA.
| 02 23, 2017
68.

Survival of tissue-resident memory T cells requires exogenous lipid uptake and metabolism.

Nature.
Pan Y, Tian T, Park CO, Lofftus SY, Mei S, Liu X, Luo C, O'Malley JT, Gehad A, Teague JE, Divito SJ, Fuhlbrigge R, Puigserver P, Krueger JG, Hotamisligil GS, Clark RA, Kupper TS.
| Mar 09, 2017
69.

Variant-aware saturating mutagenesis using multiple Cas9 nucleases identifies regulatory elements at trait-associated loci.

Nat. Genet.
Canver MC, Lessard S, Pinello L, Wu Y, Ilboudo Y, Stern EN, Needleman AJ, Galactéros F, Brugnara C, Kutlar A, McKenzie C, Reid M, Chen DD, Das PP, A Cole M, Zeng J, Kurita R, Nakamura Y, Yuan GC, Lettre G, Bauer DE, Orkin SH.
| 02 20, 2017
70.

HSP90 Shapes the Consequences of Human Genetic Variation.

Cell.
Karras GI, Yi S, Sahni N, Fischer M, Xie J, Vidal M, D'Andrea AD, Whitesell L, Lindquist S.
| Feb 23, 2017
71.

11 years' follow-up of trastuzumab after adjuvant chemotherapy in HER2-positive early breast cancer: final analysis of the HERceptin Adjuvant (HERA) trial.

Lancet.
Cameron D, Piccart-Gebhart MJ, Gelber RD, Procter M, Goldhirsch A, de Azambuja E, Castro G, Untch M, Smith I, Gianni L, Baselga J, Al-Sakaff N, Lauer S, McFadden E, Leyland-Jones B, Bell R, Dowsett M, Jackisch C.
| Mar 25, 2017
72.

Pembrolizumab as Second-Line Therapy for Advanced Urothelial Carcinoma.

N. Engl. J. Med.
Bellmunt J, de Wit R, Vaughn DJ, Fradet Y, Lee JL, Fong L, Vogelzang NJ, Climent MA, Petrylak DP, Choueiri TK, Necchi A, Gerritsen W, Gurney H, Quinn DI, Culine S, Sternberg CN, Mai Y, Poehlein CH, Perini RF, Bajorin DF, McCaffrey E.
| 03 16, 2017
73.

Phosphatidylinositol 3-kinase δ blockade increases genomic instability in B cells.

Nature.
Compagno M, Wang Q, Pighi C, Cheong TC, Meng FL, Poggio T, Yeap LS, Karaca E, Blasco RB, Langellotto F, Ambrogio C, Voena C, Wiestner A, Kasar SN, Brown JR, Sun J, Wu CJ, Gostissa M, Alt FW, Chiarle R.
| 02 23, 2017
74.

G1 cyclins link proliferation, pluripotency and differentiation of embryonic stem cells.

Nat. Cell Biol.
Liu L, Michowski W, Inuzuka H, Shimizu K, Nihira NT, Chick JM, Li N, Geng Y, Meng AY, Ordureau A, Kołodziejczyk A, Ligon KL, Bronson RT, Polyak K, Harper JW, Gygi SP, Wei W, Sicinski P.
| 02 13, 2017
75.

Aberrant corticosteroid metabolism in tumor cells enables GR takeover in enzalutamide resistant prostate cancer.

Elife.
Li J, Alyamani M, Zhang A, Chang KH, Berk M, Li Z, Zhu Z, Petro M, Magi-Galluzzi C, Taplin ME, Garcia JA, Courtney K, Klein EA, Sharifi N.
| Feb 13, 2017
76.

Tumorigenic and Immunosuppressive Effects of Endoplasmic Reticulum Stress in Cancer.

Cell.
Cubillos-Ruiz JR, Bettigole SE, Glimcher LH.
| Feb 09, 2017
77.

Understanding the Intersections between Metabolism and Cancer Biology.

Cell.
Vander Heiden MG, DeBerardinis RJ.
| Feb 09, 2017
78.

Applications of Immunogenomics to Cancer.

Cell.
Liu XS, Mardis ER.
| Feb 09, 2017
79.

Translating Germline Cancer Risk into Precision Prevention.

Cell.
Yurgelun MB, Chenevix-Trench G, Lippman SM.
| Feb 09, 2017
80.

ATXN1L, CIC, and ETS Transcription Factors Modulate Sensitivity to MAPK Pathway Inhibition.

Cell Rep.
Wang B, Krall EB, Aguirre AJ, Kim M, Widlund HR, Doshi MB, Sicinska E, Sulahian R, Goodale A, Cowley GS, Piccioni F, Doench JG, Root DE, Hahn WC.
| Feb 07, 2017