Paper Chase is a research database designed to offer abstracts of research articles published in journals that have a highly rated impact factor as determined by ISI Impact Factor and PageRank. Abstracts are organized by date, with the most recently published papers listed first. 

Paper Chase

41.

Multiplex CRISPR/Cas9-Based Genome Editing in Human Hematopoietic Stem Cells Models Clonal Hematopoiesis and Myeloid Neoplasia.

Cell Stem Cell.
Tothova Z, Krill-Burger JM, Popova KD, Landers CC, Sievers QL, Yudovich D, Belizaire R, Aster JC, Morgan EA, Tsherniak A, Ebert BL.
| Oct 05, 2017
42.

Cancer biology: Genome jail-break triggers lockdown.

Nature.
Umbreit NT, Pellman D.
| Oct 19, 2017
43.

Resistance to pyridine-based inhibitor KF116 reveals an unexpected role of integrase in HIV-1 Gag-Pol proteolytic processing.

J. Biol. Chem.
Hoyte AC, Jamin AV, Koneru PC, Kobe MJ, Larue RC, Fuchs JR, Engelman AN, Kvaratskhelia M.
| Sep 28, 2017
44.

Nuclear topology modulates the mutational landscapes of cancer genomes.

Nat. Struct. Mol. Biol.
Smith KS, Liu LL, Ganesan S, Michor F, De S.
| 10 02, 2017
45.

Coordinated Splicing of Regulatory Detained Introns within Oncogenic Transcripts Creates an Exploitable Vulnerability in Malignant Glioma.

Cancer Cell.
Braun CJ, Stanciu M, Boutz PL, Patterson JC, Calligaris D, Higuchi F, Neupane R, Fenoglio S, Cahill DP, Wakimoto H, Agar NYR, Yaffe MB, Sharp PA, Hemann MT, Lees JA.
| Oct 09, 2017
46.

Targeting neuronal activity-regulated neuroligin-3 dependency in high-grade glioma.

Nature.
Venkatesh HS, Tam LT, Woo PJ, Lennon J, Nagaraja S, Gillespie SM, Ni J, Duveau DY, Morris PJ, Zhao JJ, Thomas CJ, Monje M.
| Sep 28, 2017
47.

Epigenetic restriction of extraembryonic lineages mirrors the somatic transition to cancer.

Nature.
Smith ZD, Shi J, Gu H, Donaghey J, Clement K, Cacchiarelli D, Gnirke A, Michor F, Meissner A.
| Sep 28, 2017
48.

SMARCB1 is required for widespread BAF complex-mediated activation of enhancers and bivalent promoters.

Nat. Genet.
Nakayama RT, Pulice JL, Valencia AM, McBride MJ, McKenzie ZM, Gillespie MA, Ku WL, Teng M, Cui K, Williams RT, Cassel SH, Qing H, Widmer CJ, Demetri GD, Irizarry RA, Zhao K, Ranish JA, Kadoch C.
| 09 25, 2017
49.

Extra-mitochondrial prosurvival BCL-2 proteins regulate gene transcription by inhibiting the SUFU tumour suppressor.

Nat. Cell Biol.
Wu X, Zhang LS, Toombs J, Kuo YC, Piazza JT, Tuladhar R, Barrett Q, Fan CW, Zhang X, Walensky LD, Kool M, Cheng SY, Brekken R, Opferman JT, Green DR, Moldoveanu T, Lum L.
| 09 25, 2017
50.

PD-L1 is an activation-independent marker of brown adipocytes.

Nat Commun.
Ingram JR, Dougan M, Rashidian M, Knoll M, Keliher EJ, Garrett S, Garforth S, Blomberg OS, Espinosa C, Bhan A, Almo SC, Weissleder R, Lodish H, Dougan SK, Ploegh HL.
| Sep 21, 2017
51.

Take DAT, Flu!

Immunity.
Lobel L, Garrett WS.
| Sep 19, 2017
52.

CryoEM structure of MxB reveals a novel oligomerization interface critical for HIV restriction.

Sci Adv.
Alvarez FJD, He S, Perilla JR, Jang S, Schulten K, Engelman AN, Scheres SHW, Zhang P.
| 09 15, 2017
53.

MELK is not necessary for the proliferation of basal-like breast cancer cells.

Elife.
Huang HT, Seo HS, Zhang T, Wang Y, Jiang B, Li Q, Buckley DL, Nabet B, Roberts JM, Paulk J, Dastjerdi S, Winter GE, McLauchlan H, Moran J, Bradner JE, Eck MJ, Dhe-Paganon S, Zhao JJ, Gray NS.
| Sep 19, 2017
54.

Cell cycle-targeting microRNAs promote differentiation by enforcing cell-cycle exit.

Proc. Natl. Acad. Sci. U.S.A.
Otto T, Candido SV, Pilarz MS, Sicinska E, Bronson RT, Bowden M, Lachowicz IA, Mulry K, Fassl A, Han RC, Jecrois ES, Sicinski P.
| Oct 03, 2017
55.

Fishing for answers in precision cancer medicine.

Proc. Natl. Acad. Sci. U.S.A.
Fazio M, Zon LI.
| Sep 26, 2017
56.

Antiangiogenesis to curb urothelial cancer.

Lancet.
Bellmunt J.
| Sep 12, 2017
57.

Enhancing CD8(+) T Cell Fatty Acid Catabolism within a Metabolically Challenging Tumor Microenvironment Increases the Efficacy of Melanoma Immunotherapy.

Cancer Cell.
Zhang Y, Kurupati R, Liu L, Zhou XY, Zhang G, Hudaihed A, Filisio F, Giles-Davis W, Xu X, Karakousis GC, Schuchter LM, Xu W, Amaravadi R, Xiao M, Sadek N, Krepler C, Herlyn M, Freeman GJ, Rabinowitz JD, Ertl HCJ.
| Sep 11, 2017
58.

Scratching the Surface of Immunotherapeutic Targets in Neuroblastoma.

Cancer Cell.
Malone CF, Stegmaier K.
| 09 11, 2017
59.

Analysis of somatic microsatellite indels identifies driver events in human tumors.

Nat. Biotechnol.
Maruvka YE, Mouw KW, Karlic R, Parasuraman P, Kamburov A, Polak P, Haradhvala NJ, Hess JM, Rheinbay E, Brody Y, Koren A, Braunstein LZ, D'Andrea A, Lawrence MS, Bass A, Bernards A, Michor F, Getz G.
| 09 11, 2017
60.

Regulation of the glucocorticoid receptor via a BET-dependent enhancer drives antiandrogen resistance in prostate cancer.

Elife.
Shah N, Wang P, Wongvipat J, Karthaus WR, Abida W, Armenia J, Rockowitz S, Drier Y, Bernstein BE, Long HW, Freedman ML, Arora VK, Zheng D, Sawyers CL.
| Sep 11, 2017

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