Paper Chase is a research database designed to offer abstracts of research articles published in journals that have a highly rated impact factor as determined by ISI Impact Factor and PageRank. Abstracts are organized by date, with the most recently published papers listed first. 

Paper Chase


A New Class of Allosteric HIV-1 Integrase Inhibitors Identified by Crystallographic Fragment Screening of the Catalytic Core Domain.

J. Biol. Chem.
Patel D, Antwi J, Koneru PC, Serrao E, Forli S, Kessl JJ, Feng L, Deng N, Levy RM, Fuchs JR, Olson AJ, Engelman AN, Bauman JD, Kvaratskhelia M, Arnold E.
| Sep 19, 2016

Leveraging premalignant biology for immune-based cancer prevention.

Proc. Natl. Acad. Sci. U.S.A.
Spira A, Disis ML, Schiller JT, Vilar E, Rebbeck TR, Bejar R, Ideker T, Arts J, Yurgelun MB, Mesirov JP, Rao A, Garber J, Jaffee EM, Lippman SM.
| Sep 27, 2016

PHD3 Loss in Cancer Enables Metabolic Reliance on Fatty Acid Oxidation via Deactivation of ACC2.

Mol. Cell.
German NJ, Yoon H, Yusuf RZ, Murphy JP, Finley LW, Laurent G, Haas W, Satterstrom FK, Guarnerio J, Zaganjor E, Santos D, Pandolfi PP, Beck AH, Gygi SP, Scadden DT, Kaelin WG, Haigis MC.
| Sep 15, 2016

Treatment or Monitoring for Early Prostate Cancer.

N. Engl. J. Med.
D'Amico AV.
| Oct 13, 2016

BET Bromodomain Inhibition Promotes Anti-tumor Immunity by Suppressing PD-L1 Expression.

Cell Rep.
Zhu H, Bengsch F, Svoronos N, Rutkowski MR, Bitler BG, Allegrezza MJ, Yokoyama Y, Kossenkov AV, Bradner JE, Conejo-Garcia JR, Zhang R.
| Sep 13, 2016

Safety Study of Salmeterol in Asthma in Adults.

N. Engl. J. Med.
Hasegawa T, Uno H, Wei LJ.
| Sep 15, 2016

Tissue of origin dictates branched-chain amino acid metabolism in mutant Kras-driven cancers.

Mayers JR, Torrence ME, Danai LV, Papagiannakopoulos T, Davidson SM, Bauer MR, Lau AN, Ji BW, Dixit PD, Hosios AM, Muir A, Chin CR, Freinkman E, Jacks T, Wolpin BM, Vitkup D, Vander Heiden MG.
| Sep 9, 2016

High-throughput measurement of single-cell growth rates using serial microfluidic mass sensor arrays.

Nat. Biotechnol.
Cermak N, Olcum S, Delgado FF, Wasserman SC, Payer KR, A Murakami M, Knudsen SM, Kimmerling RJ, Stevens MM, Kikuchi Y, Sandikci A, Ogawa M, Agache V, Baléras F, Weinstock DM, Manalis SR.
| Sep 5, 2016

Transparency and availability of data for cancer research.

Fitchett JR, Sharara N, Head MG, Huang F, Atun R.
| Aug 27, 2016

Selenoprotein H is an essential regulator of redox homeostasis that cooperates with p53 in development and tumorigenesis.

Proc. Natl. Acad. Sci. U.S.A.
Cox AG, Tsomides A, Kim AJ, Saunders D, Hwang KL, Evason KJ, Heidel J, Brown KK, Yuan M, Lien EC, Lee BC, Nissim S, Dickinson B, Chhangawala S, Chang CJ, Asara JM, Houvras Y, Gladyshev VN, Goessling W.
| Sep 20, 2016

A PGC1α-mediated transcriptional axis suppresses melanoma metastasis.

Luo C, Lim JH, Lee Y, Granter SR, Thomas A, Vazquez F, Widlund HR, Puigserver P.
| Aug 31, 2016


N. Engl. J. Med.
Lampson BL, Gray SW, Cibas ES, Levy BD, Loscalzo J.
| Sep 1, 2016

Lysine-specific demethylase 1 promotes brown adipose tissue thermogenesis via repressing glucocorticoid activation.

Genes Dev.
Zeng X, Jedrychowski MP, Chen Y, Serag S, Lavery GG, Gygi SP, Spiegelman BM.
| Aug 15, 2016

pVHL suppresses kinase activity of Akt in a proline-hydroxylation-dependent manner.

Guo J, Chakraborty AA, Liu P, Gan W, Zheng X, Inuzuka H, Wang B, Zhang J, Zhang L, Yuan M, Novak J, Cheng JQ, Toker A, Signoretti S, Zhang Q, Asara JM, Kaelin WG, Wei W.
| Aug 26, 2016

Cell biology of fat storage.

Mol. Biol. Cell.
Cohen P, Spiegelman BM.
| Aug 15, 2016

Mitotic MELK-eIF4B signaling controls protein synthesis and tumor cell survival.

Proc. Natl. Acad. Sci. U.S.A.
Wang Y, Begley M, Li Q, Huang HT, Lako A, Eck MJ, Gray NS, Mitchison TJ, Cantley LC, Zhao JJ.
| Aug 30, 2016

Modulation of long noncoding RNAs by risk SNPs underlying genetic predispositions to prostate cancer.

Nat. Genet.
Guo H, Ahmed M, Zhang F, Yao CQ, Li S, Liang Y, Hua J, Soares F, Sun Y, Langstein J, Li Y, Poon C, Bailey SD, Desai K, Fei T, Li Q, Sendorek DH, Fraser M, Prensner JR, Pugh TJ, Pomerantz M, Bristow RG, Lupien M, Feng FY, Boutros PC, Freedman ML, Walsh MJ, He HH.
| Aug 15, 2016

Punctuated copy number evolution and clonal stasis in triple-negative breast cancer.

Nat. Genet.
Gao R, Davis A, McDonald TO, Sei E, Shi X, Wang Y, Tsai PC, Casasent A, Waters J, Zhang H, Meric-Bernstam F, Michor F, Navin NE.
| Aug 15, 2016