Paper Chase is a research database designed to offer abstracts of research articles published in journals that have a highly rated impact factor as determined by ISI Impact Factor and PageRank. Abstracts are organized by date, with the most recently published papers listed first. 

Paper Chase

1.

Cyclin D-CDK4 kinase destabilizes PD-L1 via Cul3(SPOP) to control cancer immune surveillance.

Nature.
Zhang J, Bu X, Wang H, Zhu Y, Geng Y, Nihira NT, Tan Y, Ci Y, Wu F, Dai X, Guo J, Huang YH, Fan C, Ren S, Sun Y, Freeman GJ, Sicinski P, Wei W.
| Nov 16, 2017
2.

Determining therapeutic susceptibility in multiple myeloma by single-cell mass accumulation.

Nat Commun.
Cetin AE, Stevens MM, Calistri NL, Fulciniti M, Olcum S, Kimmerling RJ, Munshi NC, Manalis SR.
| Nov 20, 2017
3.

A single-cell survey of the small intestinal epithelium.

Nature.
Haber AL, Biton M, Rogel N, Herbst RH, Shekhar K, Smillie C, Burgin G, Delorey TM, Howitt MR, Katz Y, Tirosh I, Beyaz S, Dionne D, Zhang M, Raychowdhury R, Garrett WS, Rozenblatt-Rosen O, Shi HN, Yilmaz O, Xavier RJ, Regev A.
| Nov 16, 2017
4.

Cancer immunotherapy: The dark side of PD-1 receptor inhibition.

Nature.
Ludin A, Zon LI.
| Nov 15, 2017
5.

SnapShot: Chronic Lymphocytic Leukemia.

Cancer Cell.
Ten Hacken E, Guièze R, Wu CJ.
| Nov 13, 2017
7.

Toddler signaling regulates mesodermal cell migration downstream of Nodal signaling.

Elife.
Norris ML, Pauli A, Gagnon JA, Lord ND, Rogers KW, Mosimann C, Zon LI, Schier AF.
| Nov 09, 2017
8.

Midostaurin in FLT3-Mutated Acute Myeloid Leukemia.

N. Engl. J. Med.
Stone RM, Larson RA, Döhner H.
| 11 09, 2017
9.

Scalable whole-exome sequencing of cell-free DNA reveals high concordance with metastatic tumors.

Nat Commun.
Adalsteinsson VA, Ha G, Freeman SS, Choudhury AD, Stover DG, Parsons HA, Gydush G, Reed SC, Rotem D, Rhoades J, Loginov D, Livitz D, Rosebrock D, Leshchiner I, Kim J, Stewart C, Rosenberg M, Francis JM, Zhang CZ, Cohen O, Oh C, Ding H, Polak P, Lloyd M, Mahmud S, Helvie K, Merrill MS, Santiago RA, O'Connor EP, Jeong SH, Leeson R, Barry RM, Kramkowski JF, Zhang Z, Polacek L, Lohr JG, Schleicher M, Lipscomb E, Saltzman A, Oliver NM, Marini L, Waks AG, Harshman LC, Tolaney SM, Van Allen EM, Winer EP, Lin NU, Nakabayashi M, Taplin ME, Johannessen CM, Garraway LA, Golub TR, Boehm JS, Wagle N, Getz G, Love JC, Meyerson M.
| Nov 06, 2017
10.

Prodomain-Growth Factor Swapping in the Structure of pro-TGF-β1.

J. Biol. Chem.
Zhao B, Xu S, Dong X, Lu C, Springer TA.
| Nov 05, 2017
11.

NMR-Directed Design of PreTCRβ and pMHC Molecules Implies a Distinct Geometry for preTCR Relative to αβTCR Recognition of pMHC.

J. Biol. Chem.
Mallis RJ, Arthanari H, Lang MJ, Reinherz EL, Wagner G.
| Nov 03, 2017
12.

A precision therapy against cancers driven by KIT/PDGFRA mutations.

Sci Transl Med.
Evans EK, Gardino AK, Kim JL, Hodous BL, Shutes A, Davis A, Zhu XJ, Schmidt-Kittler O, Wilson D, Wilson K, DiPietro L, Zhang Y, Brooijmans N, LaBranche TP, Wozniak A, Gebreyohannes YK, Schöffski P, Heinrich MC, DeAngelo DJ, Miller S, Wolf B, Kohl N, Guzi T, Lydon N, Boral A, Lengauer C.
| Nov 01, 2017
14.

Common and cell-type specific responses to anti-cancer drugs revealed by high throughput transcript profiling.

Nat Commun.
Niepel M, Hafner M, Duan Q, Wang Z, Paull EO, Chung M, Lu X, Stuart JM, Golub TR, Subramanian A, Ma'ayan A, Sorger PK.
| Oct 30, 2017
15.

Computational correction of copy number effect improves specificity of CRISPR-Cas9 essentiality screens in cancer cells.

Nat. Genet.
Meyers RM, Bryan JG, McFarland JM, Weir BA, Sizemore AE, Xu H, Dharia NV, Montgomery PG, Cowley GS, Pantel S, Goodale A, Lee Y, Ali LD, Jiang G, Lubonja R, Harrington WF, Strickland M, Wu T, Hawes DC, Zhivich VA, Wyatt MR, Kalani Z, Chang JJ, Okamoto M, Stegmaier K, Golub TR, Boehm JS, Vazquez F, Root DE, Hahn WC, Tsherniak A.
| Oct 30, 2017
16.

Resistance to checkpoint blockade therapy through inactivation of antigen presentation.

Nat Commun.
Sade-Feldman M, Jiao YJ, Chen JH, Rooney MS, Barzily-Rokni M, Eliane JP, Bjorgaard SL, Hammond MR, Vitzthum H, Blackmon SM, Frederick DT, Hazar-Rethinam M, Nadres BA, Van Seventer EE, Shukla SA, Yizhak K, Ray JP, Rosebrock D, Livitz D, Adalsteinsson V, Getz G, Duncan LM, Li B, Corcoran RB, Lawrence DP, Stemmer-Rachamimov A, Boland GM, Landau DA, Flaherty KT, Sullivan RJ, Hacohen N.
| Oct 26, 2017
17.

Overcoming mutational complexity in acute myeloid leukemia by inhibition of critical pathways.

Sci Transl Med.
Saito Y, Mochizuki Y, Ogahara I, Watanabe T, Hogdal L, Takagi S, Sato K, Kaneko A, Kajita H, Uchida N, Fukami T, Shultz LD, Taniguchi S, Ohara O, Letai AG, Ishikawa F.
| Oct 25, 2017
18.

Understanding Tissue-Specific Gene Regulation.

Cell Rep.
Sonawane AR, Platig J, Fagny M, Chen CY, Paulson JN, Lopes-Ramos CM, DeMeo DL, Quackenbush J, Glass K, Kuijjer ML.
| Oct 24, 2017
19.

BCL-XL directly modulates RAS signalling to favour cancer cell stemness.

Nat Commun.
Carné Trécesson S, Souazé F, Basseville A, Bernard AC, Pécot J, Lopez J, Bessou M, Sarosiek KA, Letai A, Barillé-Nion S, Valo I, Coqueret O, Guette C, Campone M, Gautier F, Juin PP.
| Oct 24, 2017
20.

High grade serous ovarian carcinomas originate in the fallopian tube.

Nat Commun.
Labidi-Galy SI, Papp E, Hallberg D, Niknafs N, Adleff V, Noe M, Bhattacharya R, Novak M, Jones S, Phallen J, Hruban CA, Hirsch MS, Lin DI, Schwartz L, Maire CL, Tille JC, Bowden M, Ayhan A, Wood LD, Scharpf RB, Kurman R, Wang TL, Shih IM, Karchin R, Drapkin R, Velculescu VE.
| Oct 23, 2017

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