Paper Chase is a research database designed to offer abstracts of research articles published in journals that have a highly rated impact factor as determined by ISI Impact Factor and PageRank. Abstracts are organized by date, with the most recently published papers listed first. 

Paper Chase


Targeting mutant p53 through the mevalonate pathway.

Nat. Cell Biol.
Freed-Pastor W, Prives C.
| Oct 27, 2016

The genomic landscape of schwannoma.

Nat. Genet.
Agnihotri S, Jalali S, Wilson MR, Danesh A, Li M, Klironomos G, Krieger JR, Mansouri A, Khan O, Mamatjan Y, Landon-Brace N, Tung T, Dowar M, Li T, Bruce JP, Burrell KE, Tonge PD, Alamsahebpour A, Krischek B, Agarwalla PK, Bi WL, Dunn IF, Beroukhim R, Fehlings MG, Bril V, Pagnotta SM, Iavarone A, Pugh TJ, Aldape KD, Zadeh G.
| Oct 10, 2016

Progress towards generation of human haematopoietic stem cells.

Nat. Cell Biol.
Wahlster L, Daley GQ.
| Oct 10, 2016

Protein 4.1R Influences Myogenin Protein Stability and Skeletal Muscle Differentiation.

J. Biol. Chem.
Huang SC, Zhou A, Nguyen DT, Zhang HS, Benz EJ.
| Oct 25, 2016

Suppression by TFR cells leads to durable and selective inhibition of B cell effector function.

Nat. Immunol.
Sage PT, Ron-Harel N, Juneja VR, Sen DR, Maleri S, Sungnak W, Kuchroo VK, Haining WN, Chevrier N, Haigis M, Sharpe AH.
| Oct 03, 2016

On-Target Efficacy of a HIF2α Antagonist in Preclinical Kidney Cancer Models.

Cho H, Du X, Rizzi JP, Liberzon E, Chakraborty AA, Gao W, Carvo I, Signoretti S, Bruick R, Josey JA, Wallace EM, Kaelin WG.
| Sep 05, 2016

Phenotypic Characterization of a Comprehensive Set of MAPK1/ERK2 Missense Mutants.

Cell Rep.
Brenan L, Andreev A, Cohen O, Pantel S, Kamburov A, Cacchiarelli D, Persky NS, Zhu C, Bagul M, Goetz EM, Burgin AB, Garraway LA, Getz G, Mikkelsen TS, Piccioni F, Root DE, Johannessen CM.
| Oct 18, 2016

Pre-TCRs leverage Vβ CDRs and hydrophobic patch in mechanosensing thymic self-ligands.

J. Biol. Chem.
Das DK, Mallis RJ, Duke-Cohan JS, Hussey RE, Tetteh PW, Hilton M, Wagner G, Lang MJ, Reinherz EL.
| Oct 5, 2016

Environment Dictates Dependence on Mitochondrial Complex I for NAD+ and Aspartate Production and Determines Cancer Cell Sensitivity to Metformin.

Cell Metab.
Gui DY, Sullivan LB, Luengo A, Hosios AM, Bush LN, Gitego N, Davidson SM, Freinkman E, Thomas CJ, Vander Heiden MG.
| Oct 12, 2016

Drug sensitivity of single cancer cells is predicted by changes in mass accumulation rate.

Nat. Biotechnol.
Stevens MM, Maire CL, Chou N, Murakami MA, Knoff DS, Kikuchi Y, Kimmerling RJ, Liu H, Haidar S, Calistri NL, Cermak N, Olcum S, Cordero NA, Idbaih A, Wen PY, Weinstock DM, Ligon KL, Manalis SR.
| Oct 10, 2016

Modeling of RNA-seq fragment sequence bias reduces systematic errors in transcript abundance estimation.

Nat. Biotechnol.
Love MI, Hogenesch JB, Irizarry RA.
| Sep 26, 2016

Divide and Conquer to Treat Lung Cancer.

N. Engl. J. Med.
Johnson BE.
| Oct 8, 2016

Nivolumab for Recurrent Squamous-Cell Carcinoma of the Head and Neck.

N. Engl. J. Med.
Ferris RL, Blumenschein G, Fayette J, Guigay J, Colevas AD, Licitra L, Harrington K, Kasper S, Vokes EE, Even C, Worden F, Saba NF, Iglesias Docampo LC, Haddad R, Rordorf T, Kiyota N, Tahara M, Monga M, Lynch M, Geese WJ, Kopit J, Shaw JW, Gillison ML.
| Oct 8, 2016

Ribociclib as First-Line Therapy for HR-Positive, Advanced Breast Cancer.

N. Engl. J. Med.
Hortobagyi GN, Stemmer SM, Burris HA, Yap YS, Sonke GS, Paluch-Shimon S, Campone M, Blackwell KL, André F, Winer EP, Janni W, Verma S, Conte P, Arteaga CL, Cameron DA, Petrakova K, Hart LL, Villanueva C, Chan A, Jakobsen E, Nusch A, Burdaeva O, Grischke EM, Alba E, Wist E, Marschner N, Favret AM, Yardley D, Bachelot T, Tseng LM, Blau S, Xuan F, Souami F, Miller M, Germa C, Hirawat S, O'Shaughnessy J.
| Oct 7, 2016

Niraparib Maintenance Therapy in Platinum-Sensitive, Recurrent Ovarian Cancer.

N. Engl. J. Med.
Mirza MR, Monk BJ, Herrstedt J, Oza AM, Mahner S, Redondo A, Fabbro M, Ledermann JA, Lorusso D, Vergote I, Ben-Baruch NE, Marth C, Mądry R, Christensen RD, Berek JS, Dørum A, Tinker AV, du Bois A, González-Martín A, Follana P, Benigno B, Rosenberg P, Gilbert L, Rimel BJ, Buscema J, Balser JP, Agarwal S, Matulonis UA.
| Oct 7, 2016

Prolonged Survival in Stage III Melanoma with Ipilimumab Adjuvant Therapy.

N. Engl. J. Med.
Eggermont AM, Chiarion-Sileni V, Grob JJ, Dummer R, Wolchok JD, Schmidt H, Hamid O, Robert C, Ascierto PA, Richards JM, Lebbé C, Ferraresi V, Smylie M, Weber JS, Maio M, Bastholt L, Mortier L, Thomas L, Tahir S, Hauschild A, Hassel JC, Hodi FS, Taitt C, de Pril V, de Schaetzen G, Suciu S, Testori A.
| Oct 7, 2016

Daratumumab, Lenalidomide, and Dexamethasone for Multiple Myeloma.

N. Engl. J. Med.
Dimopoulos MA, Oriol A, Nahi H, San-Miguel J, Bahlis NJ, Usmani SZ, Rabin N, Orlowski RZ, Komarnicki M, Suzuki K, Plesner T, Yoon SS, Ben Yehuda D, Richardson PG, Goldschmidt H, Reece D, Lisby S, Khokhar NZ, O'Rourke L, Chiu C, Qin X, Guckert M, Ahmadi T, Moreau P, Cochrane T.
| Oct 6, 2016

Rac1-mediated membrane raft localization of PI3K/p110β is required for its activation by GPCRs or PTEN loss.

Cizmecioglu O, Ni J, Xie S, Zhao JJ, Roberts TM.
| Oct 04, 2016

Small Molecule Inhibition of the Ubiquitin-specific Protease USP2 Accelerates Cyclin D1 Degradation and Leads to Cell Cycle Arrest in Colorectal Cancer and Mantle Cell Lymphoma Models.

J. Biol. Chem.
Davis MI, Pragani R, Fox JT, Shen M, Parmar K, Gaudiano EF, Liu L, Tanega C, McGee L, Hall MD, McKnight C, Shinn P, Nelson H, Chattopadhyay D, D'Andrea AD, Auld DS, DeLucas LJ, Li Z, Boxer MB, Simeonov A.
| Sep 28, 2016

Bromodomain Inhibitors Correct Bioenergetic Deficiency Caused by Mitochondrial Disease Complex I Mutations.

Mol. Cell.
Barrow JJ, Balsa E, Verdeguer F, Tavares CD, Soustek MS, Hollingsworth LR, Jedrychowski M, Vogel R, Paulo JA, Smeitink J, Gygi SP, Doench J, Root DE, Puigserver P.
| Oct 6, 2016