Paper Chase is a research database designed to offer abstracts of research articles published in journals that have a highly rated impact factor as determined by ISI Impact Factor and PageRank. Abstracts are organized by date, with the most recently published papers listed first. 

Paper Chase

Roles of G protein subunits in transmembrane signalling.

Nature. May 12, 1988;333(6169):129-34.
Neer EJ, Clapham DE.

Department of Medicine, Brigham and Women's Hospital Harvard Medical School, Boston, Massachusetts 02115.


A family of proteins called G proteins couples cell surface receptors to a variety of enzymes and ion channels. Since many cells contain several very similar G proteins, an important question is how signals remain specific as they cross the cell membrane.