Paper Chase is a research database designed to offer abstracts of research articles published in journals that have a highly rated impact factor as determined by ISI Impact Factor and PageRank. Abstracts are organized by date, with the most recently published papers listed first. 

Paper Chase

RNA-catalysed synthesis of complementary-strand RNA.

Nature. Jun 15, 1989;339(6225):519-22.
Doudna JA, Szostak JW.

Department of Molecular Biology, Massachusetts General Hospital, Boston 02114.


The Tetrahymena ribozyme can splice together multiple oligonucleotides aligned on a template strand to yield a fully complementary product strand. This reaction demonstrates the feasibility of RNA-catalysed RNA replications.