Paper Chase is a research database designed to offer abstracts of research articles published in journals that have a highly rated impact factor as determined by ISI Impact Factor and PageRank. Abstracts are organized by date, with the most recently published papers listed first. 

Paper Chase

Turning on brown fat and muscle metabolism: hedging your bets.

Cell. Oct 12, 2012;151(2):248-50.
Lee KY, Kahn CR.

Joslin Diabetes Center and Harvard Medical School, Boston, MA 02115, USA.


Developmental genes are essential in the formation and function of adipose tissue and muscle. In this issue of Cell, Teperino et al. demonstrate that noncanonical hedgehog signaling increases glucose uptake into brown fat and muscle. Modulation of developmental pathways may serve as a potential target for new treatments of diabetes and other metabolic disorders.