Study of brain tumor cells reveals genetic diversity underlying failure of treatments

A new study of the gene activity of hundreds of individual cells from five patients’ deadly brain tumors adds yet another layer of complexity, revealing an enormous diversity of which genes are flipped on and off in cells in the same tumor. The study, published online in the journal Science Thursday, is a collaboration that crosses the boundary between medicine and science. Brad Bernstein, professor of pathology at Massachusetts General Hospital, is one of the leaders of the study.

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