More... Share to Twitter Share to Facebook

Animal Welfare Assurance of Compliance number for grant submission: A3431-01

The Public Health Service (PHS) Policy on Humane Care and Use of Laboratory Animals (Policy) requires that institutions have an OLAW-approved Animal Welfare Assurance before carrying out any activities involving live vertebrate animals. Harvard Medical School maintains an Assurance that it will comply with the Public Health Service Policy on Humane Care and Use of Laboratory Animals. This Assurance sets forth the responsibilities and procedures of the university regarding the care and use of animals. The Assurance is applicable to all biomedical research, research training, experimentation, biological testing, and related activities involving live, vertebrate animals supported by the Public Health Service (PHS) and conducted at Harvard Medical School, Harvard School of Public Health, Harvard School of Dental Medicine, and Brigham and Women’s Hospital (collectively, the Harvard Medical Area), or at another institution as a consequence of the sub-granting or subcontracting of a PHS conducted or supported activity by the university. The Assurance of Compliance is a document that demonstrates institutional compliance with PHS policy. It requires that there be in place an Institutional Program for Animal Care and Use and an Institutional Animal Care and Use Committee (IACUC) to monitor the Program.


A variety of research activities at Harvard Medical School involve animals. Extensive effort is made to provide excellent care for animals used in research, and to minimize procedures that have potential for discomfort, distress or pain.

The Institutional Animal Care and Use Committee (IACUC) oversees the responsible use of animals in research and instructional activities. The IACUC reviews protocols, reviews the animal care and use program, and monitors the animal facilities to ensure compliance with standards and regulatory requirements.


The Harvard Medical Area Animal Care and Use Program is accredited by The Association for the Assessment and Accreditation of Laboratory Animal Care International (AAALAC).

Association for Assessment and Accreditation of Lab Animal Care International (AAALAC) number and date:
Accreditation # 000009, 6/12/13

All research activities must conform to the statutes of the Animal Welfare Act and the guidelines of the Public Health Service as issued in the Guide for the Care and Use of Laboratory Animals (revised 2010). This site provides information to help investigators at The Harvard Medical Area comply with all legal requirements and provides documents and links to information that can help improve the quality of research involving animals