Paper Chase is a research database designed to offer abstracts of research articles published in journals that have a highly rated impact factor as determined by ISI Impact Factor and PageRank. Abstracts are organized by date, with the most recently published papers listed first. 

Paper Chase

101.

Insulator dysfunction and oncogene activation in IDH mutant gliomas.

Nature.
Flavahan WA, Drier Y, Liau BB, Gillespie SM, Venteicher AS, Stemmer-Rachamimov AO, Suvà ML, Bernstein BE.
| Jan 7, 2016
102.

Harnessing RNAi-based nanomedicines for therapeutic gene silencing in B-cell malignancies.

Proc. Natl. Acad. Sci. U.S.A.
Weinstein S, Toker IA, Emmanuel R, Ramishetti S, Hazan-Halevy I, Rosenblum D, Goldsmith M, Abraham A, Benjamini O, Bairey O, Raanani P, Nagler A, Lieberman J, Peer D.
| Jan 5, 2016
103.

APOL1 kidney disease risk variants cause cytotoxicity by depleting cellular potassium and inducing stress-activated protein kinases.

Proc. Natl. Acad. Sci. U.S.A.
Olabisi OA, Zhang JY, VerPlank L, Zahler N, DiBartolo S, Heneghan JF, Schlöndorff JS, Suh JH, Yan P, Alper SL, Friedman DJ, Pollak MR.
| Jan 26, 2016
104.

Nicastrin functions to sterically hinder γ-secretase-substrate interactions driven by substrate transmembrane domain.

Proc. Natl. Acad. Sci. U.S.A.
Bolduc DM, Montagna DR, Gu Y, Selkoe DJ, Wolfe MS.
| Feb 2, 2016
105.

High risk of near-crash driving events following night-shift work.

Proc. Natl. Acad. Sci. U.S.A.
Lee ML, Howard ME, Horrey WJ, Liang Y, Anderson C, Shreeve MS, O'Brien CS, Czeisler CA.
| Jan 5, 2016
106.

Mouse embryonic fibroblasts exhibit extensive developmental and phenotypic diversity.

Proc. Natl. Acad. Sci. U.S.A.
Singhal PK, Sassi S, Lan L, Au P, Halvorsen SC, Fukumura D, Jain RK, Seed B.
| Jan 5, 2016
107.

Selexipag for the Treatment of Pulmonary Arterial Hypertension.

N. Engl. J. Med.
Sitbon O, Channick R, Chin KM, Frey A, Gaine S, Galiè N, Ghofrani HA, Hoeper MM, Lang IM, Preiss R, Rubin LJ, Di Scala L, Tapson V, Adzerikho I, Liu J, Moiseeva O, Zeng X, Simonneau G, McLaughlin VV, Williams PG, Beghetti M, Corris P, Pepke-Zaba J, Souza R, DeMets DL, Gomberg-Maitland M, Greenberg BH, Schulman S, Douketis J, Amuchastegui M.
| Dec 24, 2015
108.

Resensitization to Crizotinib by the Lorlatinib ALK Resistance Mutation L1198F.

N. Engl. J. Med.
Shaw AT, Friboulet L, Leshchiner I, Gainor JF, Bergqvist S, Brooun A, Burke BJ, Deng YL, Liu W, Dardaei L, Frias RL, Schultz KR, Logan J, James LP, Smeal T, Timofeevski S, Katayama R, Iafrate AJ, Le L, McTigue M, Getz G, Johnson TW, Engelman JA.
| Jan 7, 2016
109.

Tau-driven 26S proteasome impairment and cognitive dysfunction can be prevented early in disease by activating cAMP-PKA signaling.

Nat. Med.
Myeku N, Clelland CL, Emrani S, Kukushkin NV, Yu WH, Goldberg AL, Duff KE.
| 12 21, 2015
110.

Genetic Identification of an Expansive Mechanoreceptor Sensitive to Skin Stroking.

Cell.
Bai L, Lehnert BP, Liu J, Neubarth NL, Dickendesher TL, Nwe PH, Cassidy C, Woodbury CJ, Ginty DD.
| Dec 17, 2015
111.

Not All Created Equal: Lineage Hard-Wiring in the Production of Blood.

Cell.
Mercier FE, Scadden DT.
| Dec 17, 2015
112.

Limiting Cholesterol Biosynthetic Flux Spontaneously Engages Type I IFN Signaling.

Cell.
York AG, Williams KJ, Argus JP, Zhou QD, Brar G, Vergnes L, Gray EE, Zhen A, Wu NC, Yamada DH, Cunningham CR, Tarling EJ, Wilks MQ, Casero D, Gray DH, Yu AK, Wang ES, Brooks DG, Sun R, Kitchen SG, Wu TT, Reue K, Stetson DB, Bensinger SJ.
| Dec 17, 2015
113.

ReEBOV Antigen Rapid Test kit for Ebola - Authors' reply.

Lancet.
Broadhurst MJ, Semper A, Bailey D, Pollock NR.
| Dec 5, 2015
114.

Autoinflammation and autoimmunity in systemic juvenile idiopathic arthritis.

Proc. Natl. Acad. Sci. U.S.A.
Nigrovic PA.
| Dec 29, 2015
115.

Hydroxycarbamide versus chronic transfusion for maintenance of transcranial doppler flow velocities in children with sickle cell anaemia-TCD With Transfusions Changing to Hydroxyurea (TWiTCH): a multicentre, open-label, phase 3, non-inferiority trial.

Lancet.
Ware RE, Davis BR, Schultz WH, Brown RC, Aygun B, Sarnaik S, Odame I, Fuh B, George A, Owen W, Luchtman-Jones L, Rogers ZR, Hilliard L, Gauger C, Piccone C, Lee MT, Kwiatkowski JL, Jackson S, Miller ST, Roberts C, Heeney MM, Kalfa TA, Nelson S, Imran H, Nottage K, Alvarez O, Rhodes M, Thompson AA, Rothman JA, Helton KJ, Roberts D, Coleman J, Bonner MJ, Kutlar A, Patel N, Wood J, Piller L, Wei P, Luden J, Mortier NA, Stuber SE, Luban NL, Cohen AR, Pressel S, Adams RJ.
| Dec 4, 2015
116.

cAMP-induced phosphorylation of 26S proteasomes on Rpn6/PSMD11 enhances their activity and the degradation of misfolded proteins.

Proc. Natl. Acad. Sci. U.S.A.
Lokireddy S, Kukushkin NV, Goldberg AL.
| Dec 29, 2015
117.

mTOR inhibition activates overall protein degradation by the ubiquitin proteasome system as well as by autophagy.

Proc. Natl. Acad. Sci. U.S.A.
Zhao J, Zhai B, Gygi SP, Goldberg AL.
| Dec 29, 2015
119.

Ezh2 regulates differentiation and function of natural killer cells through histone methyltransferase activity.

Proc. Natl. Acad. Sci. U.S.A.
Yin J, Leavenworth JW, Li Y, Luo Q, Xie H, Liu X, Huang S, Yan H, Fu Z, Zhang LY, Zhang L, Hao J, Wu X, Deng X, Roberts CW, Orkin SH, Cantor H, Wang X.
| Dec 29, 2015
120.

The histone chaperone CAF-1 safeguards somatic cell identity.

Nature.
Cheloufi S, Elling U, Hopfgartner B, Jung YL, Murn J, Ninova M, Hubmann M, Badeaux AI, Euong Ang C, Tenen D, Wesche DJ, Abazova N, Hogue M, Tasdemir N, Brumbaugh J, Rathert P, Jude J, Ferrari F, Blanco A, Fellner M, Wenzel D, Zinner M, Vidal SE, Bell O, Stadtfeld M, Chang HY, Almouzni G, Lowe SW, Rinn J, Wernig M, Aravin A, Shi Y, Park PJ, Penninger JM, Zuber J, Hochedlinger K.
| Dec 10, 2015