Paper Chase is a research database designed to offer abstracts of research articles published in journals that have a highly rated impact factor as determined by ISI Impact Factor and PageRank. Abstracts are organized by date, with the most recently published papers listed first. 

Paper Chase


Alternative pathway of insulin signalling in mice with targeted disruption of the IRS-1 gene.

Araki E, Lipes MA, Patti ME, Brüning JC, Haag B, Johnson RS, Kahn CR.
| Nov 10, 1994

Identification of multiple genes in bovine retinal pericytes altered by exposure to elevated levels of glucose by using mRNA differential display.

Proc. Natl. Acad. Sci. U.S.A.
Aiello LP, Robinson GS, Lin YW, Nishio Y, King GL.
| Jun 21, 1994

Picking a research problem. The critical decision.

N. Engl. J. Med.
Kahn CR.
| May 26, 1994

Substitution of the erbB-2 oncoprotein transmembrane domain activates the insulin receptor and modulates the action of insulin and insulin-receptor substrate 1.

Proc. Natl. Acad. Sci. U.S.A.
Cheatham B, Shoelson SE, Yamada K, Goncalves E, Kahn CR.
| Aug 1, 1993

Tight glucose control and diabetic complications.

Wang PH.
| Jul 17, 1993

Optimizing transmembrane domain helicity accelerates insulin receptor internalization and lateral mobility.

Proc. Natl. Acad. Sci. U.S.A.
Goncalves E, Yamada K, Thatte HS, Backer JM, Golan DE, Kahn CR, Shoelson SE.
| Jun 15, 1993

Insulin receptor substrate 1 mediates insulin and insulin-like growth factor I-stimulated maturation of Xenopus oocytes.

Proc. Natl. Acad. Sci. U.S.A.
Chuang LM, Myers MG, Seidner GA, Birnbaum MJ, White MF, Kahn CR.
| Jun 1, 1993

Progression to diabetes in nonobese diabetic (NOD) mice with transgenic T cell receptors.

Lipes MA, Rosenzweig A, Tan KN, Tanigawa G, Ladd D, Seidman JG, Eisenbarth GS.
| Feb 19, 1993

IRS-1 activates phosphatidylinositol 3'-kinase by associating with src homology 2 domains of p85.

Proc. Natl. Acad. Sci. U.S.A.
Myers MG, Backer JM, Sun XJ, Shoelson S, Hu P, Schlessinger J, Yoakim M, Schaffhausen B, White MF.
| Nov 1, 1992

YMXM motifs of IRS-1 define substrate specificity of the insulin receptor kinase.

Proc. Natl. Acad. Sci. U.S.A.
Shoelson SE, Chatterjee S, Chaudhuri M, White MF.
| Mar 15, 1992

Enhanced insulin-like growth factor I gene expression in regenerating rat pancreas.

Proc. Natl. Acad. Sci. U.S.A.
Smith FE, Rosen KM, Villa-Komaroff L, Weir GC, Bonner-Weir S.
| Jul 15, 1991

Structure of the insulin receptor substrate IRS-1 defines a unique signal transduction protein.

Sun XJ, Rothenberg P, Kahn CR, Backer JM, Araki E, Wilden PA, Cahill DA, Goldstein BJ, White MF.
| Jul 4, 1991

The insulin receptor with phenylalanine replacing tyrosine-1146 provides evidence for separate signals regulating cellular metabolism and growth.

Proc. Natl. Acad. Sci. U.S.A.
Wilden PA, Backer JM, Kahn CR, Cahill DA, Schroeder GJ, White MF.
| 5 1, 1990

Partial diversion of a mutant proinsulin (B10 aspartic acid) from the regulated to the constitutive secretory pathway in transfected AtT-20 cells.

Proc. Natl. Acad. Sci. U.S.A.
Gross DJ, Halban PA, Kahn CR, Weir GC, Villa-Komaroff L.
| 6 1, 1989

trans-activation of RNA polymerase II and III promoters by SV40 small t antigen.

Loeken M, Bikel I, Livingston DM, Brady J.
| Dec 23, 1988

Mutation of the insulin receptor at tyrosine 960 inhibits signal transmission but does not affect its tyrosine kinase activity.

White MF, Livingston JN, Backer JM, Lauris V, Dull TJ, Ullrich A, Kahn CR.
| Aug 26, 1988