Paper Chase is a research database designed to offer abstracts of research articles published in journals that have a highly rated impact factor as determined by ISI Impact Factor and PageRank. Abstracts are organized by date, with the most recently published papers listed first. 

Paper Chase


No evidence that selection has been less effective at removing deleterious mutations in Europeans than in Africans.

Nat. Genet.
Do R, Balick D, Li H, Adzhubei I, Sunyaev S, Reich D.
| 01 12, 2015

Metabolism. Lysosomal amino acid transporter SLC38A9 signals arginine sufficiency to mTORC1.

Wang S, Tsun ZY, Wolfson RL, Shen K, Wyant GA, Plovanich ME, Yuan ED, Jones TD, Chantranupong L, Comb W, Wang T, Bar-Peled L, Zoncu R, Straub C, Kim C, Park J, Sabatini BL, Sabatini DM.
| Jan 9, 2015

Shadow enhancers enable Hunchback bifunctionality in the Drosophila embryo.

Proc. Natl. Acad. Sci. U.S.A.
Staller MV, Vincent BJ, Bragdon MD, Lydiard-Martin T, Wunderlich Z, Estrada J, DePace AH.
| Jan 20, 2015

Association between 7 years of intensive treatment of type 1 diabetes and long-term mortality.

Orchard TJ, Nathan DM, Zinman B, Cleary P, Brillon D, Backlund JY, Lachin JM.
| Jan 6, 2015

K-Ras4A splice variant is widely expressed in cancer and uses a hybrid membrane-targeting motif.

Proc. Natl. Acad. Sci. U.S.A.
Tsai FD, Lopes MS, Zhou M, Court H, Ponce O, Fiordalisi JJ, Gierut JJ, Cox AD, Haigis KM, Philips MR.
| Jan 20, 2015

Structure-inherent targeting of near-infrared fluorophores for parathyroid and thyroid gland imaging.

Nat. Med.
Hyun H, Park MH, Owens EA, Wada H, Henary M, Handgraaf HJ, Vahrmeijer AL, Frangioni JV, Choi HS.
| 01 05, 2015

Control of PI(3) kinase in Treg cells maintains homeostasis and lineage stability.

Nat. Immunol.
Huynh A, DuPage M, Priyadharshini B, Sage PT, Quiros J, Borges CM, Townamchai N, Gerriets VA, Rathmell JC, Sharpe AH, Bluestone JA, Turka LA.
| 01 05, 2015

High-density mapping of the MHC identifies a shared role for HLA-DRB1*01:03 in inflammatory bowel diseases and heterozygous advantage in ulcerative colitis.

Nat. Genet.
Goyette P, Boucher G, Mallon D, Ellinghaus E, Jostins L, Huang H, Ripke S, Gusareva ES, Annese V, Hauser SL, Oksenberg JR, Thomsen I, Leslie S, Daly MJ, Van Steen K, Duerr RH, Barrett JC, McGovern DP, Schumm LP, Traherne JA, Carrington MN, Kosmoliaptsis V, Karlsen TH, Franke A, Rioux JD.
| 01 05, 2015

The amyloidogenic V122I transthyretin variant in elderly black Americans.

N. Engl. J. Med.
Quarta CC, Buxbaum JN, Shah AM, Falk RH, Claggett B, Kitzman DW, Mosley TH, Butler KR, Boerwinkle E, Solomon SD.
| Jan 1, 2015

Appearance and disappearance of the mRNA signature characteristic of Treg cells in visceral adipose tissue: age, diet, and PPARγ effects.

Proc. Natl. Acad. Sci. U.S.A.
Cipolletta D, Cohen P, Spiegelman BM, Benoist C, Mathis D.
| Jan 13, 2015

Intracellular osteopontin regulates homeostasis and function of natural killer cells.

Proc. Natl. Acad. Sci. U.S.A.
Leavenworth JW, Verbinnen B, Wang Q, Shen E, Cantor H.
| Jan 13, 2015

INK4 locus of the tumor-resistant rodent, the naked mole rat, expresses a functional p15/p16 hybrid isoform.

Proc. Natl. Acad. Sci. U.S.A.
Tian X, Azpurua J, Ke Z, Augereau A, Zhang ZD, Vijg J, Gladyshev VN, Gorbunova V, Seluanov A.
| Jan 27, 2015

Optogenetic activation of cholinergic neurons in the PPT or LDT induces REM sleep.

Proc. Natl. Acad. Sci. U.S.A.
Van Dort CJ, Zachs DP, Kenny JD, Zheng S, Goldblum RR, Gelwan NA, Ramos DM, Nolan MA, Wang K, Weng FJ, Lin Y, Wilson MA, Brown EN.
| Jan 13, 2015

Polymeric synthetic nanoparticles for the induction of antigen-specific immunological tolerance.

Proc. Natl. Acad. Sci. U.S.A.
Maldonado RA, LaMothe RA, Ferrari JD, Zhang AH, Rossi RJ, Kolte PN, Griset AP, O'Neil C, Altreuter DH, Browning E, Johnston L, Farokhzad OC, Langer R, Scott DW, von Andrian UH, Kishimoto TK.
| Jan 13, 2015

Cohort of birth modifies the association between FTO genotype and BMI.

Proc. Natl. Acad. Sci. U.S.A.
Rosenquist JN, Lehrer SF, O'Malley AJ, Zaslavsky AM, Smoller JW, Christakis NA.
| Jan 13, 2015

Inducible RNAi in vivo reveals that the transcription factor BATF is required to initiate but not maintain CD8+ T-cell effector differentiation.

Proc. Natl. Acad. Sci. U.S.A.
Godec J, Cowley GS, Barnitz RA, Root DE, Sharpe AH, Haining WN.
| Jan 13, 2015

Surgery for Crohn's disease: look harder, act faster.

Ananthakrishnan AN.
| Apr 11, 2015

Genomic responses to inflammation in mouse models mimic humans: we concur, apples to oranges comparisons won't do.

Proc. Natl. Acad. Sci. U.S.A.
Shay T, Lederer JA, Benoist C.
| Jan 27, 2015