Paper Chase is a research database designed to offer abstracts of research articles published in journals that have a highly rated impact factor as determined by ISI Impact Factor and PageRank. Abstracts are organized by date, with the most recently published papers listed first. 

Paper Chase

1.

Cytisine--a tobacco treatment hiding in plain sight.

N. Engl. J. Med.
Rigotti NA.
| Dec 18, 2014
2.

Dauer-independent insulin/IGF-1-signalling implicates collagen remodelling in longevity.

Nature.
Ewald CY, Landis JN, Abate JP, Murphy CT, Blackwell TK.
| Dec 15, 2014
4.

Genetic modifiers of EGFR dependence in non-small cell lung cancer.

Proc. Natl. Acad. Sci. U.S.A.
Sharifnia T, Rusu V, Piccioni F, Bagul M, Imielinski M, Cherniack AD, Pedamallu CS, Wong B, Wilson FH, Garraway LA, Altshuler D, Golub TR, Root DE, Subramanian A, Meyerson M.
| Dec 15, 2014
5.

Complementary genomic approaches highlight the PI3K/mTOR pathway as a common vulnerability in osteosarcoma.

Proc. Natl. Acad. Sci. U.S.A.
Perry JA, Kiezun A, Tonzi P, Van Allen EM, Carter SL, Baca SC, Cowley GS, Bhatt AS, Rheinbay E, Pedamallu CS, Helman E, Taylor-Weiner A, McKenna A, DeLuca DS, Lawrence MS, Ambrogio L, Sougnez C, Sivachenko A, Walensky LD, Wagle N, Mora J, de Torres C, Lavarino C, Dos Santos Aguiar S, Yunes JA, Brandalise SR, Mercado-Celis GE, Melendez-Zajgla J, Cárdenas-Cardós R, Velasco-Hidalgo L, Roberts CW, Garraway LA, Rodriguez-Galindo C, Gabriel SB, Lander ES, Golub TR, Orkin SH, Getz G, Janeway KA.
| Dec 15, 2014
6.

Stable, uncleaved HIV-1 envelope glycoprotein gp140 forms a tightly folded trimer with a native-like structure.

Proc. Natl. Acad. Sci. U.S.A.
Kovacs JM, Noeldeke E, Ha HJ, Peng H, Rits-Volloch S, Harrison SC, Chen B.
| Dec 15, 2014
7.

Testosterone Replacement Therapy Faces FDA Scrutiny.

JAMA.
Garnick MB.
| Dec 11, 2014
8.

A 3D Map of the Human Genome at Kilobase Resolution Reveals Principles of Chromatin Looping.

Cell.
Rao SS, Huntley MH, Durand NC, Stamenova EK, Bochkov ID, Robinson JT, Sanborn AL, Machol I, Omer AD, Lander ES, Aiden EL.
| Dec 11, 2014
9.

The Disease of the Little Paper.

N. Engl. J. Med.
Koven S.
| Dec 11, 2014
10.

Genome-scale transcriptional activation by an engineered CRISPR-Cas9 complex.

Nature.
Konermann S, Brigham MD, Trevino AE, Joung J, Abudayyeh OO, Barcena C, Hsu PD, Habib N, Gootenberg JS, Nishimasu H, Nureki O, Zhang F.
| Dec 10, 2014
11.

Progesterone for Traumatic Brain Injury - Resisting the Sirens' Song.

N. Engl. J. Med.
Schwamm LH.
| Dec 10, 2014
12.

Certifying the good physician: a work in progress.

JAMA.
Lee TH.
| Dec 10, 2014
13.

A piece of my mind. Art and the uncertainty of medicine.

JAMA.
Campbell JI.
| Dec 10, 2014
14.

HSP90 empowers evolution of resistance to hormonal therapy in human breast cancer models.

Proc. Natl. Acad. Sci. U.S.A.
Whitesell L, Santagata S, Mendillo ML, Lin NU, Proia DA, Lindquist S.
| Dec 8, 2014
15.

Exome sequencing identifies rare LDLR and APOA5 alleles conferring risk for myocardial infarction.

Nature.
Do R, Stitziel NO, Won HH, Jørgensen AB, Duga S, Angelica Merlini P, Kiezun A, Farrall M, Goel A, Zuk O, Guella I, Asselta R, Lange LA, Peloso GM, Auer PL, Girelli D, Martinelli N, Farlow DN, DePristo MA, Roberts R, Stewart AF, Saleheen D, Danesh J, Epstein SE, Sivapalaratnam S, Kees Hovingh G, Kastelein JJ, Samani NJ, Schunkert H, Erdmann J, Shah SH, Kraus WE, Davies R, Nikpay M, Johansen CT, Wang J, Hegele RA, Hechter E, Marz W, Kleber ME, Huang J, Johnson AD, Li M, Burke GL, Gross M, Liu Y, Assimes TL, Heiss G, Lange EM, Folsom AR, Taylor HA, Olivieri O, Hamsten A, Clarke R, Reilly DF, Yin W, Rivas MA, Donnelly P, Rossouw JE, Psaty BM, Herrington DM, Wilson JG, Rich SS, Bamshad MJ, Tracy RP, Adrienne Cupples L, Rader DJ, Reilly MP, Spertus JA, Cresci S, Hartiala J, Wilson Tang WH, Hazen SL, Allayee H, Reiner AP, Carlson CS, Kooperberg C, Jackson RD, Boerwinkle E, Lander ES, Schwartz SM, Siscovick DS, McPherson R, Tybjaerg-Hansen A, Abecasis GR, Watkins H, Nickerson DA, Ardissino D, Sunyaev SR, O'Donnell CJ, Altshuler D, Gabriel S, Kathiresan S.
| Dec 10, 2014
16.

The Ashwell-Morell receptor regulates hepatic thrombopoietin production via JAK2-STAT3 signaling.

Nat. Med.
Grozovsky R, Begonja AJ, Liu K, Visner G, Hartwig JH, Falet H, Hoffmeister KM.
| Dec 8, 2014
17.

Mutations in G protein β subunits promote transformation and kinase inhibitor resistance.

Nat. Med.
Yoda A, Adelmant G, Tamburini J, Chapuy B, Shindoh N, Yoda Y, Weigert O, Kopp N, Wu SC, Kim SS, Liu H, Tivey T, Christie AL, Elpek KG, Card J, Gritsman K, Gotlib J, Deininger MW, Makishima H, Turley SJ, Javidi-Sharifi N, Maciejewski JP, Jaiswal S, Ebert BL, Rodig SJ, Tyner JW, Marto JA, Weinstock DM, Lane AA.
| Dec 8, 2014
18.

Making (Anti)Sense of Factor XI in Thrombosis.

N. Engl. J. Med.
Flaumenhaft R.
| Dec 7, 2014
19.

PD-1 Blockade with Nivolumab in Relapsed or Refractory Hodgkin's Lymphoma.

N. Engl. J. Med.
Ansell SM, Lesokhin AM, Borrello I, Halwani A, Scott EC, Gutierrez M, Schuster SJ, Millenson MM, Cattry D, Freeman GJ, Rodig SJ, Chapuy B, Ligon AH, Zhu L, Grosso JF, Kim SY, Timmerman JM, Shipp MA, Armand P.
| Dec 6, 2014
20.

IgG4-related disease.

Lancet.
Kamisawa T, Zen Y, Pillai S, Stone JH.
| Dec 3, 2014