Paper Chase is a research database designed to offer abstracts of research articles published in journals that have a highly rated impact factor as determined by ISI Impact Factor and PageRank. Abstracts are organized by date, with the most recently published papers listed first. 

Paper Chase

161.

Efficacy and safety of regorafenib for advanced gastrointestinal stromal tumours after failure of imatinib and sunitinib (GRID): an international, multicentre, randomised, placebo-controlled, phase 3 trial.

Lancet.
Demetri GD, Reichardt P, Kang YK, Blay JY, Rutkowski P, Gelderblom H, Hohenberger P, Leahy M, von Mehren M, Joensuu H, Badalamenti G, Blackstein M, Le Cesne A, Schöffski P, Maki RG, Bauer S, Nguyen BB, Xu J, Nishida T, Chung J, Kappeler C, Kuss I, Laurent D, Casali PG, Samonigg H.
| Jan 26, 2013
162.

Influence of threonine metabolism on S-adenosylmethionine and histone methylation.

Science.
Shyh-Chang N, Locasale JW, Lyssiotis CA, Zheng Y, Teo RY, Ratanasirintrawoot S, Zhang J, Onder T, Unternaehrer JJ, Zhu H, Asara JM, Daley GQ, Cantley LC.
| Jan 11, 2013
163.

Patients' expectations about effects of chemotherapy for advanced cancer.

N. Engl. J. Med.
Weeks JC, Catalano PJ, Cronin A, Finkelman MD, Mack JW, Keating NL, Schrag D.
| Oct 25, 2012
164.

Aspirin use, tumor PIK3CA mutation, and colorectal-cancer survival.

N. Engl. J. Med.
Liao X, Lochhead P, Nishihara R, Morikawa T, Kuchiba A, Yamauchi M, Imamura Y, Qian ZR, Baba Y, Shima K, Sun R, Nosho K, Meyerhardt JA, Giovannucci E, Fuchs CS, Chan AT, Ogino S.
| Oct 25, 2012
165.

Estrogen receptor prevents p53-dependent apoptosis in breast cancer.

Proc. Natl. Acad. Sci. U.S.A.
Bailey ST, Shin H, Westerling T, Liu XS, Brown M.
| Oct 30, 2012
166.

Altered hematopoiesis in trisomy 21 as revealed through in vitro differentiation of isogenic human pluripotent cells.

Proc. Natl. Acad. Sci. U.S.A.
Maclean GA, Menne TF, Guo G, Sanchez DJ, Park IH, Daley GQ, Orkin SH.
| Oct 23, 2012
167.

TRPV4 is a regulator of adipose oxidative metabolism, inflammation, and energy homeostasis.

Cell.
Ye L, Kleiner S, Wu J, Sah R, Gupta RK, Banks AS, Cohen P, Khandekar MJ, Boström P, Mepani RJ, Laznik D, Kamenecka TM, Song X, Liedtke W, Mootha VK, Puigserver P, Griffin PR, Clapham DE, Spiegelman BM.
| Sep 28, 2012
168.

Oncogenic NRAS signaling differentially regulates survival and proliferation in melanoma.

Nat. Med.
Kwong LN, Costello JC, Liu H, Jiang S, Helms TL, Langsdorf AE, Jakubosky D, Genovese G, Muller FL, Jeong JH, Bender RP, Chu GC, Flaherty KT, Wargo JA, Collins JJ, Chin L.
| 09 16, 2012
169.

MYD88 L265P somatic mutation in Waldenström's macroglobulinemia.

N. Engl. J. Med.
Treon SP, Xu L, Yang G, Zhou Y, Liu X, Cao Y, Sheehy P, Manning RJ, Patterson CJ, Tripsas C, Arcaini L, Pinkus GS, Rodig SJ, Sohani AR, Harris NL, Laramie JM, Skifter DA, Lincoln SE, Hunter ZR.
| Aug 30, 2012
170.

An integrated transcriptional regulatory circuit that reinforces the breast cancer stem cell state.

Proc. Natl. Acad. Sci. U.S.A.
Polytarchou C, Iliopoulos D, Struhl K.
| Sep 4, 2012
171.

Functional analysis of receptor tyrosine kinase mutations in lung cancer identifies oncogenic extracellular domain mutations of ERBB2.

Proc. Natl. Acad. Sci. U.S.A.
Greulich H, Kaplan B, Mertins P, Chen TH, Tanaka KE, Yun CH, Zhang X, Lee SH, Cho J, Ambrogio L, Liao R, Imielinski M, Banerji S, Berger AH, Lawrence MS, Zhang J, Pho NH, Walker SR, Winckler W, Getz G, Frank D, Hahn WC, Eck MJ, Mani DR, Jaffe JD, Carr SA, Wong KK, Meyerson M.
| Sep 4, 2012
172.

Cancer vulnerabilities unveiled by genomic loss.

Cell.
Nijhawan D, Zack TI, Ren Y, Strickland MR, Lamothe R, Schumacher SE, Tsherniak A, Besche HC, Rosenbluh J, Shehata S, Cowley GS, Weir BA, Goldberg AL, Mesirov JP, Root DE, Bhatia SN, Beroukhim R, Hahn WC.
| Aug 17, 2012
173.

Clinical decisions. Screening for prostate cancer.

N. Engl. J. Med.
D'Amico AV, Smith MR.
| Aug 16, 2012
175.

Interpreting cancer genomes using systematic host network perturbations by tumour virus proteins.

Nature.
Rozenblatt-Rosen O, Deo RC, Padi M, Adelmant G, Calderwood MA, Rolland T, Grace M, Dricot A, Askenazi M, Tavares M, Pevzner SJ, Abderazzaq F, Byrdsong D, Carvunis AR, Chen AA, Cheng J, Correll M, Duarte M, Fan C, Feltkamp MC, Ficarro SB, Franchi R, Garg BK, Gulbahce N, Hao T, Holthaus AM, James R, Korkhin A, Litovchick L, Mar JC, Pak TR, Rabello S, Rubio R, Shen Y, Singh S, Spangle JM, Tasan M, Wanamaker S, Webber JT, Roecklein-Canfield J, Johannsen E, Barabási AL, Beroukhim R, Kieff E, Cusick ME, Hill DE, Münger K, Marto JA, Quackenbush J, Roth FP, DeCaprio JA, Vidal M.
| Jul 26, 2012
176.

Dual blockade of lipid and cyclin-dependent kinases induces synthetic lethality in malignant glioma.

Proc. Natl. Acad. Sci. U.S.A.
Cheng CK, Gustafson WC, Charron E, Houseman BT, Zunder E, Goga A, Gray NS, Pollok B, Oakes SA, James CD, Shokat KM, Weiss WA, Fan QW.
| Jul 31, 2012
177.

Dopamine receptor D3 regulates endocytic sorting by a Prazosin-sensitive interaction with the coatomer COPI.

Proc. Natl. Acad. Sci. U.S.A.
Zhang X, Wang W, Bedigian AV, Coughlin ML, Mitchison TJ, Eggert US.
| Jul 31, 2012
178.

Beige adipocytes are a distinct type of thermogenic fat cell in mouse and human.

Cell.
Wu J, Boström P, Sparks LM, Ye L, Choi JH, Giang AH, Khandekar M, Virtanen KA, Nuutila P, Schaart G, Huang K, Tu H, van Marken Lichtenbelt WD, Hoeks J, Enerbäck S, Schrauwen P, Spiegelman BM.
| Jul 20, 2012
179.

Genetic and functional analyses implicate the NUDT11, HNF1B, and SLC22A3 genes in prostate cancer pathogenesis.

Proc. Natl. Acad. Sci. U.S.A.
Grisanzio C, Werner L, Takeda D, Awoyemi BC, Pomerantz MM, Yamada H, Sooriakumaran P, Robinson BD, Leung R, Schinzel AC, Mills I, Ross-Adams H, Neal DE, Kido M, Yamamoto T, Petrozziello G, Stack EC, Lis R, Kantoff PW, Loda M, Sartor O, Egawa S, Tewari AK, Hahn WC, Freedman ML.
| Jul 10, 2012
180.

Proteasomal degradation resolves competition between cell polarization and cellular wound healing.

Cell.
Kono K, Saeki Y, Yoshida S, Tanaka K, Pellman D.
| Jul 6, 2012