Paper Chase is a research database designed to offer abstracts of research articles published in journals that have a highly rated impact factor as determined by ISI Impact Factor and PageRank. Abstracts are organized by date, with the most recently published papers listed first. 

Paper Chase

121.

(R)-2-hydroxyglutarate is sufficient to promote leukemogenesis and its effects are reversible.

Science.
Losman JA, Looper RE, Koivunen P, Lee S, Schneider RK, McMahon C, Cowley GS, Root DE, Ebert BL, Kaelin WG.
| Mar 29, 2013
122.

Service: an essential component of graduate medical education.

N. Engl. J. Med.
Kesselheim JC, Cassel CK.
| Feb 7, 2013
123.

Integrative eQTL-based analyses reveal the biology of breast cancer risk loci.

Cell.
Li Q, Seo JH, Stranger B, McKenna A, Pe'er I, Laframboise T, Brown M, Tyekucheva S, Freedman ML.
| Jan 31, 2013
124.

Cancer. Cancer cell phenotypes, in fifty shades of grey.

Science.
Marusyk A, Polyak K.
| Feb 1, 2013
125.

Genomic sequencing of meningiomas identifies oncogenic SMO and AKT1 mutations.

Nat. Genet.
Brastianos PK, Horowitz PM, Santagata S, Jones RT, McKenna A, Getz G, Ligon KL, Palescandolo E, Van Hummelen P, Ducar MD, Raza A, Sunkavalli A, Macconaill LE, Stemmer-Rachamimov AO, Louis DN, Hahn WC, Dunn IF, Beroukhim R.
| 01 20, 2013
126.

Whole-exome sequencing identifies a recurrent NAB2-STAT6 fusion in solitary fibrous tumors.

Nat. Genet.
Chmielecki J, Crago AM, Rosenberg M, O'Connor R, Walker SR, Ambrogio L, Auclair D, McKenna A, Heinrich MC, Frank DA, Meyerson M.
| 01 13, 2013
127.

Crystal structure of the HLA-DM-HLA-DR1 complex defines mechanisms for rapid peptide selection.

Cell.
Pos W, Sethi DK, Call MJ, Schulze MS, Anders AK, Pyrdol J, Wucherpfennig KW.
| Dec 21, 2012
128.

β-Catenin-driven cancers require a YAP1 transcriptional complex for survival and tumorigenesis.

Cell.
Rosenbluh J, Nijhawan D, Cox AG, Li X, Neal JT, Schafer EJ, Zack TI, Wang X, Tsherniak A, Schinzel AC, Shao DD, Schumacher SE, Weir BA, Vazquez F, Cowley GS, Root DE, Mesirov JP, Beroukhim R, Kuo CJ, Goessling W, Hahn WC.
| Dec 21, 2012
129.

EZH2 oncogenic activity in castration-resistant prostate cancer cells is Polycomb-independent.

Science.
Xu K, Wu ZJ, Groner AC, He HH, Cai C, Lis RT, Wu X, Stack EC, Loda M, Liu T, Xu H, Cato L, Thornton JE, Gregory RI, Morrissey C, Vessella RL, Montironi R, Magi-Galluzzi C, Kantoff PW, Balk SP, Liu XS, Brown M.
| Dec 14, 2012
130.

Signaling axis involving Hedgehog, Notch, and Scl promotes the embryonic endothelial-to-hematopoietic transition.

Proc. Natl. Acad. Sci. U.S.A.
Kim PG, Albacker CE, Lu YF, Jang IH, Lim Y, Heffner GC, Arora N, Bowman TV, Lin MI, Lensch MW, De Los Angeles A, Zon LI, Loewer S, Daley GQ.
| Jan 8, 2013
131.

A PGC-1α isoform induced by resistance training regulates skeletal muscle hypertrophy.

Cell.
Ruas JL, White JP, Rao RR, Kleiner S, Brannan KT, Harrison BC, Greene NP, Wu J, Estall JL, Irving BA, Lanza IR, Rasbach KA, Okutsu M, Nair KS, Yan Z, Leinwand LA, Spiegelman BM.
| Dec 7, 2012
132.

Cellular alchemy and the golden age of reprogramming.

Cell.
Daley GQ.
| Dec 7, 2012
133.

Efficacy and safety of regorafenib for advanced gastrointestinal stromal tumours after failure of imatinib and sunitinib (GRID): an international, multicentre, randomised, placebo-controlled, phase 3 trial.

Lancet.
Demetri GD, Reichardt P, Kang YK, Blay JY, Rutkowski P, Gelderblom H, Hohenberger P, Leahy M, von Mehren M, Joensuu H, Badalamenti G, Blackstein M, Le Cesne A, Schöffski P, Maki RG, Bauer S, Nguyen BB, Xu J, Nishida T, Chung J, Kappeler C, Kuss I, Laurent D, Casali PG, Samonigg H.
| Jan 26, 2013
134.

Influence of threonine metabolism on S-adenosylmethionine and histone methylation.

Science.
Shyh-Chang N, Locasale JW, Lyssiotis CA, Zheng Y, Teo RY, Ratanasirintrawoot S, Zhang J, Onder T, Unternaehrer JJ, Zhu H, Asara JM, Daley GQ, Cantley LC.
| Jan 11, 2013
135.

Patients' expectations about effects of chemotherapy for advanced cancer.

N. Engl. J. Med.
Weeks JC, Catalano PJ, Cronin A, Finkelman MD, Mack JW, Keating NL, Schrag D.
| Oct 25, 2012
136.

Aspirin use, tumor PIK3CA mutation, and colorectal-cancer survival.

N. Engl. J. Med.
Liao X, Lochhead P, Nishihara R, Morikawa T, Kuchiba A, Yamauchi M, Imamura Y, Qian ZR, Baba Y, Shima K, Sun R, Nosho K, Meyerhardt JA, Giovannucci E, Fuchs CS, Chan AT, Ogino S.
| Oct 25, 2012
137.

Estrogen receptor prevents p53-dependent apoptosis in breast cancer.

Proc. Natl. Acad. Sci. U.S.A.
Bailey ST, Shin H, Westerling T, Liu XS, Brown M.
| Oct 30, 2012
138.

Altered hematopoiesis in trisomy 21 as revealed through in vitro differentiation of isogenic human pluripotent cells.

Proc. Natl. Acad. Sci. U.S.A.
Maclean GA, Menne TF, Guo G, Sanchez DJ, Park IH, Daley GQ, Orkin SH.
| Oct 23, 2012
139.

TRPV4 is a regulator of adipose oxidative metabolism, inflammation, and energy homeostasis.

Cell.
Ye L, Kleiner S, Wu J, Sah R, Gupta RK, Banks AS, Cohen P, Khandekar MJ, Boström P, Mepani RJ, Laznik D, Kamenecka TM, Song X, Liedtke W, Mootha VK, Puigserver P, Griffin PR, Clapham DE, Spiegelman BM.
| Sep 28, 2012
140.

Oncogenic NRAS signaling differentially regulates survival and proliferation in melanoma.

Nat. Med.
Kwong LN, Costello JC, Liu H, Jiang S, Helms TL, Langsdorf AE, Jakubosky D, Genovese G, Muller FL, Jeong JH, Bender RP, Chu GC, Flaherty KT, Wargo JA, Collins JJ, Chin L.
| 09 16, 2012