Paper Chase is a research database designed to offer abstracts of research articles published in journals that have a highly rated impact factor as determined by ISI Impact Factor and PageRank. Abstracts are organized by date, with the most recently published papers listed first. 

Paper Chase

41.

Normalizing the environment recapitulates adult human immune traits in laboratory mice.

Nature.
Beura LK, Hamilton SE, Bi K, Schenkel JM, Odumade OA, Casey KA, Thompson EA, Fraser KA, Rosato PC, Filali-Mouhim A, Sekaly RP, Jenkins MK, Vezys V, Haining WN, Jameson SC, Masopust D.
| Apr 28, 2016
42.

Association of Pembrolizumab With Tumor Response and Survival Among Patients With Advanced Melanoma.

JAMA.
Ribas A, Hamid O, Daud A, Hodi FS, Wolchok JD, Kefford R, Joshua AM, Patnaik A, Hwu WJ, Weber JS, Gangadhar TC, Hersey P, Dronca R, Joseph RW, Zarour H, Chmielowski B, Lawrence DP, Algazi A, Rizvi NA, Hoffner B, Mateus C, Gergich K, Lindia JA, Giannotti M, Li XN, Ebbinghaus S, Kang SP, Robert C.
| Apr 19, 2016
43.

Controllability analysis of the directed human protein interaction network identifies disease genes and drug targets.

Proc. Natl. Acad. Sci. U.S.A.
Vinayagam A, Gibson TE, Lee HJ, Yilmazel B, Roesel C, Hu Y, Kwon Y, Sharma A, Liu YY, Perrimon N, Barabási AL.
| May 3, 2016
44.

Core Circadian Clock Genes Regulate Leukemia Stem Cells in AML.

Cell.
Puram RV, Kowalczyk MS, de Boer CG, Schneider RK, Miller PG, McConkey M, Tothova Z, Tejero H, Heckl D, Järås M, Chen MC, Li H, Tamayo A, Cowley GS, Rozenblatt-Rosen O, Al-Shahrour F, Regev A, Ebert BL.
| Apr 7, 2016
45.

Insight into GATA1 transcriptional activity through interrogation of cis elements disrupted in human erythroid disorders.

Proc. Natl. Acad. Sci. U.S.A.
Wakabayashi A, Ulirsch JC, Ludwig LS, Fiorini C, Yasuda M, Choudhuri A, McDonel P, Zon LI, Sankaran VG.
| Apr 19, 2016
46.

Reporter nanoparticle that monitors its anticancer efficacy in real time.

Proc. Natl. Acad. Sci. U.S.A.
Kulkarni A, Rao P, Natarajan S, Goldman A, Sabbisetti VS, Khater Y, Korimerla N, Chandrasekar V, Mashelkar RA, Sengupta S.
| Apr 12, 2016
47.

Cullin-RING ubiquitin E3 ligase regulation by the COP9 signalosome.

Nature.
Cavadini S, Fischer ES, Bunker RD, Potenza A, Lingaraju GM, Goldie KN, Mohamed WI, Faty M, Petzold G, Beckwith RE, Tichkule RB, Hassiepen U, Abdulrahman W, Pantelic RS, Matsumoto S, Sugasawa K, Stahlberg H, Thomä NH.
| Mar 31, 2016
48.

Mitochondrial ROS regulate thermogenic energy expenditure and sulfenylation of UCP1.

Nature.
Chouchani ET, Kazak L, Jedrychowski MP, Lu GZ, Erickson BK, Szpyt J, Pierce KA, Laznik-Bogoslavski D, Vetrivelan R, Clish CB, Robinson AJ, Gygi SP, Spiegelman BM.
| Apr 7, 2016
49.

Lessons from a bridge generation.

Science.
Segal RA.
| Mar 25, 2016
50.

Survey of variation in human transcription factors reveals prevalent DNA binding changes.

Science.
Barrera LA, Vedenko A, Kurland JV, Rogers JM, Gisselbrecht SS, Rossin EJ, Woodard J, Mariani L, Kock KH, Inukai S, Siggers T, Shokri L, Gordân R, Sahni N, Cotsapas C, Hao T, Yi S, Kellis M, Daly MJ, Vidal M, Hill DE, Bulyk ML.
| Mar 25, 2016
51.

CANCER. The oncogene makes its escape.

Science.
Wala J, Beroukhim R.
| Mar 25, 2016
52.

A role for iron deficiency in dopaminergic neurodegeneration.

Proc. Natl. Acad. Sci. U.S.A.
Yien YY, Paw BH.
| Mar 29, 2016
53.

SARS-like WIV1-CoV poised for human emergence.

Proc. Natl. Acad. Sci. U.S.A.
Menachery VD, Yount BL, Sims AC, Debbink K, Agnihothram SS, Gralinski LE, Graham RL, Scobey T, Plante JA, Royal SR, Swanstrom J, Sheahan TP, Pickles RJ, Corti D, Randell SH, Lanzavecchia A, Marasco WA, Baric RS.
| Mar 15, 2016
54.

Adjuvant sunitinib or sorafenib for high-risk, non-metastatic renal-cell carcinoma (ECOG-ACRIN E2805): a double-blind, placebo-controlled, randomised, phase 3 trial.

Lancet.
Haas NB, Manola J, Uzzo RG, Flaherty KT, Wood CG, Kane C, Jewett M, Dutcher JP, Atkins MB, Pins M, Wilding G, Cella D, Wagner L, Matin S, Kuzel TM, Sexton WJ, Wong YN, Choueiri TK, Pili R, Puzanov I, Kohli M, Stadler W, Carducci M, Coomes R, DiPaola RS.
| May 14, 2016
56.

Atezolizumab in patients with locally advanced and metastatic urothelial carcinoma who have progressed following treatment with platinum-based chemotherapy: a single-arm, multicentre, phase 2 trial.

Lancet.
Rosenberg JE, Hoffman-Censits J, Powles T, van der Heijden MS, Balar AV, Necchi A, Dawson N, O'Donnell PH, Balmanoukian A, Loriot Y, Srinivas S, Retz MM, Grivas P, Joseph RW, Galsky MD, Fleming MT, Petrylak DP, Perez-Gracia JL, Burris HA, Castellano D, Canil C, Bellmunt J, Bajorin D, Nickles D, Bourgon R, Frampton GM, Cui N, Mariathasan S, Abidoye O, Fine GD, Dreicer R.
| May 7, 2016
57.

Clonal neoantigens elicit T cell immunoreactivity and sensitivity to immune checkpoint blockade.

Science.
McGranahan N, Furness AJ, Rosenthal R, Ramskov S, Lyngaa R, Saini SK, Jamal-Hanjani M, Wilson GA, Birkbak NJ, Hiley CT, Watkins TB, Shafi S, Murugaesu N, Mitter R, Akarca AU, Linares J, Marafioti T, Henry JY, Van Allen EM, Miao D, Schilling B, Schadendorf D, Garraway LA, Makarov V, Rizvi NA, Snyder A, Hellmann MD, Merghoub T, Wolchok JD, Shukla SA, Wu CJ, Peggs KS, Chan TA, Hadrup SR, Quezada SA, Swanton C.
| Mar 25, 2016
58.

The cellular origins of drug resistance in cancer.

Nat. Med.
Oxnard GR.
| 3 4, 2016
59.

High-fat diet enhances stemness and tumorigenicity of intestinal progenitors.

Nature.
Beyaz S, Mana MD, Roper J, Kedrin D, Saadatpour A, Hong SJ, Bauer-Rowe KE, Xifaras ME, Akkad A, Arias E, Pinello L, Katz Y, Shinagare S, Abu-Remaileh M, Mihaylova MM, Lamming DW, Dogum R, Guo G, Bell GW, Selig M, Nielsen GP, Gupta N, Ferrone CR, Deshpande V, Yuan GC, Orkin SH, Sabatini DM, Yilmaz ÖH.
| Mar 3, 2016
60.

Stem cells: Dietary fat promotes intestinal dysregulation.

Nature.
Luo C, Puigserver P.
| Mar 3, 2016