Paper Chase is a research database designed to offer abstracts of research articles published in journals that have a highly rated impact factor as determined by ISI Impact Factor and PageRank. Abstracts are organized by date, with the most recently published papers listed first. 

Paper Chase

181.

TRPV4 is a regulator of adipose oxidative metabolism, inflammation, and energy homeostasis.

Cell.
Ye L, Kleiner S, Wu J, Sah R, Gupta RK, Banks AS, Cohen P, Khandekar MJ, Boström P, Mepani RJ, Laznik D, Kamenecka TM, Song X, Liedtke W, Mootha VK, Puigserver P, Griffin PR, Clapham DE, Spiegelman BM.
| Sep 28, 2012
182.

Oncogenic NRAS signaling differentially regulates survival and proliferation in melanoma.

Nat. Med.
Kwong LN, Costello JC, Liu H, Jiang S, Helms TL, Langsdorf AE, Jakubosky D, Genovese G, Muller FL, Jeong JH, Bender RP, Chu GC, Flaherty KT, Wargo JA, Collins JJ, Chin L.
| 09 16, 2012
183.

MYD88 L265P somatic mutation in Waldenström's macroglobulinemia.

N. Engl. J. Med.
Treon SP, Xu L, Yang G, Zhou Y, Liu X, Cao Y, Sheehy P, Manning RJ, Patterson CJ, Tripsas C, Arcaini L, Pinkus GS, Rodig SJ, Sohani AR, Harris NL, Laramie JM, Skifter DA, Lincoln SE, Hunter ZR.
| Aug 30, 2012
184.

An integrated transcriptional regulatory circuit that reinforces the breast cancer stem cell state.

Proc. Natl. Acad. Sci. U.S.A.
Polytarchou C, Iliopoulos D, Struhl K.
| Sep 4, 2012
185.

Functional analysis of receptor tyrosine kinase mutations in lung cancer identifies oncogenic extracellular domain mutations of ERBB2.

Proc. Natl. Acad. Sci. U.S.A.
Greulich H, Kaplan B, Mertins P, Chen TH, Tanaka KE, Yun CH, Zhang X, Lee SH, Cho J, Ambrogio L, Liao R, Imielinski M, Banerji S, Berger AH, Lawrence MS, Zhang J, Pho NH, Walker SR, Winckler W, Getz G, Frank D, Hahn WC, Eck MJ, Mani DR, Jaffe JD, Carr SA, Wong KK, Meyerson M.
| Sep 4, 2012
186.

Cancer vulnerabilities unveiled by genomic loss.

Cell.
Nijhawan D, Zack TI, Ren Y, Strickland MR, Lamothe R, Schumacher SE, Tsherniak A, Besche HC, Rosenbluh J, Shehata S, Cowley GS, Weir BA, Goldberg AL, Mesirov JP, Root DE, Bhatia SN, Beroukhim R, Hahn WC.
| Aug 17, 2012
187.

Clinical decisions. Screening for prostate cancer.

N. Engl. J. Med.
D'Amico AV, Smith MR.
| Aug 16, 2012
189.

Interpreting cancer genomes using systematic host network perturbations by tumour virus proteins.

Nature.
Rozenblatt-Rosen O, Deo RC, Padi M, Adelmant G, Calderwood MA, Rolland T, Grace M, Dricot A, Askenazi M, Tavares M, Pevzner SJ, Abderazzaq F, Byrdsong D, Carvunis AR, Chen AA, Cheng J, Correll M, Duarte M, Fan C, Feltkamp MC, Ficarro SB, Franchi R, Garg BK, Gulbahce N, Hao T, Holthaus AM, James R, Korkhin A, Litovchick L, Mar JC, Pak TR, Rabello S, Rubio R, Shen Y, Singh S, Spangle JM, Tasan M, Wanamaker S, Webber JT, Roecklein-Canfield J, Johannsen E, Barabási AL, Beroukhim R, Kieff E, Cusick ME, Hill DE, Münger K, Marto JA, Quackenbush J, Roth FP, DeCaprio JA, Vidal M.
| Jul 26, 2012
190.

Dual blockade of lipid and cyclin-dependent kinases induces synthetic lethality in malignant glioma.

Proc. Natl. Acad. Sci. U.S.A.
Cheng CK, Gustafson WC, Charron E, Houseman BT, Zunder E, Goga A, Gray NS, Pollok B, Oakes SA, James CD, Shokat KM, Weiss WA, Fan QW.
| Jul 31, 2012
191.

Dopamine receptor D3 regulates endocytic sorting by a Prazosin-sensitive interaction with the coatomer COPI.

Proc. Natl. Acad. Sci. U.S.A.
Zhang X, Wang W, Bedigian AV, Coughlin ML, Mitchison TJ, Eggert US.
| Jul 31, 2012
192.

Beige adipocytes are a distinct type of thermogenic fat cell in mouse and human.

Cell.
Wu J, Boström P, Sparks LM, Ye L, Choi JH, Giang AH, Khandekar M, Virtanen KA, Nuutila P, Schaart G, Huang K, Tu H, van Marken Lichtenbelt WD, Hoeks J, Enerbäck S, Schrauwen P, Spiegelman BM.
| Jul 20, 2012
193.

Genetic and functional analyses implicate the NUDT11, HNF1B, and SLC22A3 genes in prostate cancer pathogenesis.

Proc. Natl. Acad. Sci. U.S.A.
Grisanzio C, Werner L, Takeda D, Awoyemi BC, Pomerantz MM, Yamada H, Sooriakumaran P, Robinson BD, Leung R, Schinzel AC, Mills I, Ross-Adams H, Neal DE, Kido M, Yamamoto T, Petrozziello G, Stack EC, Lis R, Kantoff PW, Loda M, Sartor O, Egawa S, Tewari AK, Hahn WC, Freedman ML.
| Jul 10, 2012
194.

Proteasomal degradation resolves competition between cell polarization and cellular wound healing.

Cell.
Kono K, Saeki Y, Yoshida S, Tanaka K, Pellman D.
| Jul 6, 2012
195.

Proto-genes and de novo gene birth.

Nature.
Carvunis AR, Rolland T, Wapinski I, Calderwood MA, Yildirim MA, Simonis N, Charloteaux B, Hidalgo CA, Barbette J, Santhanam B, Brar GA, Weissman JS, Regev A, Thierry-Mieg N, Cusick ME, Vidal M.
| Jul 19, 2012
196.

Autocrine activation of the MET receptor tyrosine kinase in acute myeloid leukemia.

Nat. Med.
Kentsis A, Reed C, Rice KL, Sanda T, Rodig SJ, Tholouli E, Christie A, Valk PJ, Delwel R, Ngo V, Kutok JL, Dahlberg SE, Moreau LA, Byers RJ, Christensen JG, Vande Woude G, Licht JD, Kung AL, Staudt LM, Look AT.
| 3 30, 2011
197.

Development of insulin resistance in mice lacking PGC-1α in adipose tissues.

Proc. Natl. Acad. Sci. U.S.A.
Kleiner S, Mepani RJ, Laznik D, Ye L, Jurczak MJ, Jornayvaz FR, Estall JL, Chatterjee Bhowmick D, Shulman GI, Spiegelman BM.
| Jun 12, 2012
198.

EGFR in limbo.

Cell.
Eck MJ, Hahn WC.
| May 11, 2012
199.

A unifying model for mTORC1-mediated regulation of mRNA translation.

Nature.
Thoreen CC, Chantranupong L, Keys HR, Wang T, Gray NS, Sabatini DM.
| May 3, 2012
200.

Oncogenic Kras maintains pancreatic tumors through regulation of anabolic glucose metabolism.

Cell.
Ying H, Kimmelman AC, Lyssiotis CA, Hua S, Chu GC, Fletcher-Sananikone E, Locasale JW, Son J, Zhang H, Coloff JL, Yan H, Wang W, Chen S, Viale A, Zheng H, Paik JH, Lim C, Guimaraes AR, Martin ES, Chang J, Hezel AF, Perry SR, Hu J, Gan B, Xiao Y, Asara JM, Weissleder R, Wang YA, Chin L, Cantley LC, DePinho RA.
| Apr 27, 2012