Paper Chase is a research database designed to offer abstracts of research articles published in journals that have a highly rated impact factor as determined by ISI Impact Factor and PageRank. Abstracts are organized by date, with the most recently published papers listed first. 

Paper Chase

41.

mTORC1 induces purine synthesis through control of the mitochondrial tetrahydrofolate cycle.

Science.
Ben-Sahra I, Hoxhaj G, Ricoult SJ, Asara JM, Manning BD.
| Feb 12, 2016
42.

A small-molecule inhibitor of sarcomere contractility suppresses hypertrophic cardiomyopathy in mice.

Science.
Green EM, Wakimoto H, Anderson RL, Evanchik MJ, Gorham JM, Harrison BC, Henze M, Kawas R, Oslob JD, Rodriguez HM, Song Y, Wan W, Leinwand LA, Spudich JA, McDowell RS, Seidman JG, Seidman CE.
| Feb 5, 2016
43.

Isolation of potent neutralizing antibodies from a survivor of the 2014 Ebola virus outbreak.

Science.
Bornholdt ZA, Turner HL, Murin CD, Li W, Sok D, Souders CA, Piper AE, Goff A, Shamblin JD, Wollen SE, Sprague TR, Fusco ML, Pommert KB, Cavacini LA, Smith HL, Klempner M, Reimann KA, Krauland E, Gerngross TU, Wittrup KD, Saphire EO, Burton DR, Glass PJ, Ward AB, Walker LM.
| Mar 4, 2016
44.

MTAP deletion confers enhanced dependency on the PRMT5 arginine methyltransferase in cancer cells.

Science.
Kryukov GV, Wilson FH, Ruth JR, Paulk J, Tsherniak A, Marlow SE, Vazquez F, Weir BA, Fitzgerald ME, Tanaka M, Bielski CM, Scott JM, Dennis C, Cowley GS, Boehm JS, Root DE, Golub TR, Clish CB, Bradner JE, Hahn WC, Garraway LA.
| Mar 11, 2016
45.

Tuft cells, taste-chemosensory cells, orchestrate parasite type 2 immunity in the gut.

Science.
Howitt MR, Lavoie S, Michaud M, Blum AM, Tran SV, Weinstock JV, Gallini CA, Redding K, Margolskee RF, Osborne LC, Artis D, Garrett WS.
| Mar 18, 2016
46.

A zebrafish melanoma model reveals emergence of neural crest identity during melanoma initiation.

Science.
Kaufman CK, Mosimann C, Fan ZP, Yang S, Thomas AJ, Ablain J, Tan JL, Fogley RD, van Rooijen E, Hagedorn EJ, Ciarlo C, White RM, Matos DA, Puller AC, Santoriello C, Liao EC, Young RA, Zon LI.
| Jan 29, 2016
47.

Transcription factors LRF and BCL11A independently repress expression of fetal hemoglobin.

Science.
Masuda T, Wang X, Maeda M, Canver MC, Sher F, Funnell AP, Fisher C, Suciu M, Martyn GE, Norton LJ, Zhu C, Kurita R, Nakamura Y, Xu J, Higgs DR, Crossley M, Bauer DE, Orkin SH, Kharchenko PV, Maeda T.
| Jan 15, 2016
48.

Visa rules imperil collaboration.

Science.
Madani N.
| Jan 15, 2016
49.

De novo mutations in congenital heart disease with neurodevelopmental and other congenital anomalies.

Science.
Homsy J, Zaidi S, Shen Y, Ware JS, Samocha KE, Karczewski KJ, DePalma SR, McKean D, Wakimoto H, Gorham J, Jin SC, Deanfield J, Giardini A, Porter GA, Kim R, Bilguvar K, López-Giráldez F, Tikhonova I, Mane S, Romano-Adesman A, Qi H, Vardarajan B, Ma L, Daly M, Roberts AE, Russell MW, Mital S, Newburger JW, Gaynor JW, Breitbart RE, Iossifov I, Ronemus M, Sanders SJ, Kaltman JR, Seidman JG, Brueckner M, Gelb BD, Goldmuntz E, Lifton RP, Seidman CE, Chung WK.
| Dec 4, 2015
51.

Accurate concentration control of mitochondria and nucleoids.

Science.
Jajoo R, Jung Y, Huh D, Viana MP, Rafelski SM, Springer M, Paulsson J.
| Jan 8, 2016
52.

Multidrug evolutionary strategies to reverse antibiotic resistance.

Science.
Baym M, Stone LK, Kishony R.
| Jan 1, 2016
53.

In vivo gene editing in dystrophic mouse muscle and muscle stem cells.

Science.
Tabebordbar M, Zhu K, Cheng JK, Chew WL, Widrick JJ, Yan WX, Maesner C, Wu EY, Xiao R, Ran FA, Cong L, Zhang F, Vandenberghe LH, Church GM, Wagers AJ.
| Jan 22, 2016
54.

In vivo genome editing improves muscle function in a mouse model of Duchenne muscular dystrophy.

Science.
Nelson CE, Hakim CH, Ousterout DG, Thakore PI, Moreb EA, Castellanos Rivera RM, Madhavan S, Pan X, Ran FA, Yan WX, Asokan A, Zhang F, Duan D, Gersbach CA.
| Jan 22, 2016
55.

The M.D.-Ph.D. double agent.

Science.
Tsai JW.
| Dec 11, 2015
56.

Rationally engineered Cas9 nucleases with improved specificity.

Science.
Slaymaker IM, Gao L, Zetsche B, Scott DA, Yan WX, Zhang F.
| Jan 1, 2016
57.

Vitamin C selectively kills KRAS and BRAF mutant colorectal cancer cells by targeting GAPDH.

Science.
Yun J, Mullarky E, Lu C, Bosch KN, Kavalier A, Rivera K, Roper J, Chio II, Giannopoulou EG, Rago C, Muley A, Asara JM, Paik J, Elemento O, Chen Z, Pappin DJ, Dow LE, Papadopoulos N, Gross SS, Cantley LC.
| Dec 11, 2015
58.

Gate control of mechanical itch by a subpopulation of spinal cord interneurons.

Science.
Bourane S, Duan B, Koch SC, Dalet A, Britz O, Garcia-Campmany L, Kim E, Cheng L, Ghosh A, Ma Q, Goulding M.
| Oct 30, 2015
59.

Transcription factor trapping by RNA in gene regulatory elements.

Science.
Sigova AA, Abraham BJ, Ji X, Molinie B, Hannett NM, Guo YE, Jangi M, Giallourakis CC, Sharp PA, Young RA.
| Nov 20, 2015
60.

Stable inhibitory activity of regulatory T cells requires the transcription factor Helios.

Science.
Kim HJ, Barnitz RA, Kreslavsky T, Brown FD, Moffett H, Lemieux ME, Kaygusuz Y, Meissner T, Holderried TA, Chan S, Kastner P, Haining WN, Cantor H.
| Oct 16, 2015