Paper Chase is a research database designed to offer abstracts of research articles published in journals that have a highly rated impact factor as determined by ISI Impact Factor and PageRank. Abstracts are organized by date, with the most recently published papers listed first. 

Paper Chase

21.

Survey of variation in human transcription factors reveals prevalent DNA binding changes.

Science.
Barrera LA, Vedenko A, Kurland JV, Rogers JM, Gisselbrecht SS, Rossin EJ, Woodard J, Mariani L, Kock KH, Inukai S, Siggers T, Shokri L, Gordân R, Sahni N, Cotsapas C, Hao T, Yi S, Kellis M, Daly MJ, Vidal M, Hill DE, Bulyk ML.
| Mar 25, 2016
22.

CANCER. The oncogene makes its escape.

Science.
Wala J, Beroukhim R.
| Mar 25, 2016
23.

SCS macrophages suppress melanoma by restricting tumor-derived vesicle-B cell interactions.

Science.
Pucci F, Garris C, Lai CP, Newton A, Pfirschke C, Engblom C, Alvarez D, Sprachman M, Evavold C, Magnuson A, von Andrian UH, Glatz K, Breakefield XO, Mempel TR, Weissleder R, Pittet MJ.
| Apr 8, 2016
24.

Schedule-dependent interaction between anticancer treatments.

Science.
Chen SH, Forrester W, Lahav G.
| Mar 11, 2016
25.

Rare variant in scavenger receptor BI raises HDL cholesterol and increases risk of coronary heart disease.

Science.
Zanoni P, Khetarpal SA, Larach DB, Hancock-Cerutti WF, Millar JS, Cuchel M, DerOhannessian S, Kontush A, Surendran P, Saleheen D, Trompet S, Jukema JW, De Craen A, Deloukas P, Sattar N, Ford I, Packard C, Majumder Aa, Alam DS, Di Angelantonio E, Abecasis G, Chowdhury R, Erdmann J, Nordestgaard BG, Nielsen SF, Tybjærg-Hansen A, Schmidt RF, Kuulasmaa K, Liu DJ, Perola M, Blankenberg S, Salomaa V, Männistö S, Amouyel P, Arveiler D, Ferrieres J, Müller-Nurasyid M, Ferrario M, Kee F, Willer CJ, Samani N, Schunkert H, Butterworth AS, Howson JM, Peloso GM, Stitziel NO, Danesh J, Kathiresan S, Rader DJ, Watson S.
| Mar 11, 2016
26.

Stochastic activation of a DNA damage response causes cell-to-cell mutation rate variation.

Science.
Uphoff S, Lord ND, Okumus B, Potvin-Trottier L, Sherratt DJ, Paulsson J.
| Mar 4, 2016
27.

Response to Comment on "Estimating the reproducibility of psychological science".

Science.
Anderson CJ, Bahník Š, Barnett-Cowan M, Bosco FA, Chandler J, Chartier CR, Cheung F, Christopherson CD, Cordes A, Cremata EJ, Della Penna N, Estel V, Fedor A, Fitneva SA, Frank MC, Grange JA, Hartshorne JK, Hasselman F, Henninger F, van der Hulst M, Jonas KJ, Lai CK, Levitan CA, Miller JK, Moore KS, Meixner JM, Munafò MR, Neijenhuijs KI, Nilsonne G, Nosek BA, Plessow F, Prenoveau JM, Ricker AA, Schmidt K, Spies JR, Stieger S, Strohminger N, Sullivan GB, van Aert RC, van Assen MA, Vanpaemel W, Vianello M, Voracek M, Zuni K.
| Mar 4, 2016
28.

Clonal neoantigens elicit T cell immunoreactivity and sensitivity to immune checkpoint blockade.

Science.
McGranahan N, Furness AJ, Rosenthal R, Ramskov S, Lyngaa R, Saini SK, Jamal-Hanjani M, Wilson GA, Birkbak NJ, Hiley CT, Watkins TB, Shafi S, Murugaesu N, Mitter R, Akarca AU, Linares J, Marafioti T, Henry JY, Van Allen EM, Miao D, Schilling B, Schadendorf D, Garraway LA, Makarov V, Rizvi NA, Snyder A, Hellmann MD, Merghoub T, Wolchok JD, Shukla SA, Wu CJ, Peggs KS, Chan TA, Hadrup SR, Quezada SA, Swanton C.
| Mar 25, 2016
29.

Health and population effects of rare gene knockouts in adult humans with related parents.

Science.
Narasimhan VM, Hunt KA, Mason D, Baker CL, Karczewski KJ, Barnes MR, Barnett AH, Bates C, Bellary S, Bockett NA, Giorda K, Griffiths CJ, Hemingway H, Jia Z, Kelly MA, Khawaja HA, Lek M, McCarthy S, McEachan R, O'Donnell-Luria A, Paigen K, Parisinos CA, Sheridan E, Southgate L, Tee L, Thomas M, Xue Y, Schnall-Levin M, Petkov PM, Tyler-Smith C, Maher ER, Trembath RC, MacArthur DG, Wright J, Durbin R, van Heel DA.
| Apr 22, 2016
30.

Hypoxia as a therapy for mitochondrial disease.

Science.
Jain IH, Zazzeron L, Goli R, Alexa K, Schatzman-Bone S, Dhillon H, Goldberger O, Peng J, Shalem O, Sanjana NE, Zhang F, Goessling W, Zapol WM, Mootha VK.
| Apr 1, 2016
31.

Structural and molecular basis for Ebola virus neutralization by protective human antibodies.

Science.
Misasi J, Gilman MS, Kanekiyo M, Gui M, Cagigi A, Mulangu S, Corti D, Ledgerwood JE, Lanzavecchia A, Cunningham J, Muyembe-Tamfun JJ, Baxa U, Graham BS, Xiang Y, Sullivan NJ, McLellan JS.
| Mar 18, 2016
32.

Rpn1 provides adjacent receptor sites for substrate binding and deubiquitination by the proteasome.

Science.
Shi Y, Chen X, Elsasser S, Stocks BB, Tian G, Lee BH, Shi Y, Zhang N, de Poot SA, Tuebing F, Sun S, Vannoy J, Tarasov SG, Engen JR, Finley D, Walters KJ.
| Feb 19, 2016
33.

Cellular neuroscience. Differences among astrocytes.

Science.
Stevens B, Muthukumar AK.
| Feb 19, 2016
34.

Immunology. How does the immune system tolerate food?

Science.
Kuhn C, Weiner HL.
| Feb 19, 2016
35.

mTORC1 induces purine synthesis through control of the mitochondrial tetrahydrofolate cycle.

Science.
Ben-Sahra I, Hoxhaj G, Ricoult SJ, Asara JM, Manning BD.
| Feb 12, 2016
36.

A small-molecule inhibitor of sarcomere contractility suppresses hypertrophic cardiomyopathy in mice.

Science.
Green EM, Wakimoto H, Anderson RL, Evanchik MJ, Gorham JM, Harrison BC, Henze M, Kawas R, Oslob JD, Rodriguez HM, Song Y, Wan W, Leinwand LA, Spudich JA, McDowell RS, Seidman JG, Seidman CE.
| Feb 5, 2016
37.

Isolation of potent neutralizing antibodies from a survivor of the 2014 Ebola virus outbreak.

Science.
Bornholdt ZA, Turner HL, Murin CD, Li W, Sok D, Souders CA, Piper AE, Goff A, Shamblin JD, Wollen SE, Sprague TR, Fusco ML, Pommert KB, Cavacini LA, Smith HL, Klempner M, Reimann KA, Krauland E, Gerngross TU, Wittrup KD, Saphire EO, Burton DR, Glass PJ, Ward AB, Walker LM.
| Mar 4, 2016
38.

MTAP deletion confers enhanced dependency on the PRMT5 arginine methyltransferase in cancer cells.

Science.
Kryukov GV, Wilson FH, Ruth JR, Paulk J, Tsherniak A, Marlow SE, Vazquez F, Weir BA, Fitzgerald ME, Tanaka M, Bielski CM, Scott JM, Dennis C, Cowley GS, Boehm JS, Root DE, Golub TR, Clish CB, Bradner JE, Hahn WC, Garraway LA.
| Mar 11, 2016
39.

Tuft cells, taste-chemosensory cells, orchestrate parasite type 2 immunity in the gut.

Science.
Howitt MR, Lavoie S, Michaud M, Blum AM, Tran SV, Weinstock JV, Gallini CA, Redding K, Margolskee RF, Osborne LC, Artis D, Garrett WS.
| Mar 18, 2016
40.

A zebrafish melanoma model reveals emergence of neural crest identity during melanoma initiation.

Science.
Kaufman CK, Mosimann C, Fan ZP, Yang S, Thomas AJ, Ablain J, Tan JL, Fogley RD, van Rooijen E, Hagedorn EJ, Ciarlo C, White RM, Matos DA, Puller AC, Santoriello C, Liao EC, Young RA, Zon LI.
| Jan 29, 2016