Paper Chase is a research database designed to offer abstracts of research articles published in journals that have a highly rated impact factor as determined by ISI Impact Factor and PageRank. Abstracts are organized by date, with the most recently published papers listed first. 

Paper Chase

21.

HSP70 sequestration by free α-globin promotes ineffective erythropoiesis in β-thalassaemia.

Nature.
Arlet JB, Ribeil JA, Guillem F, Negre O, Hazoume A, Marcion G, Beuzard Y, Dussiot M, Moura IC, Demarest S, de Beauchêne IC, Belaid-Choucair Z, Sevin M, Maciel TT, Auclair C, Leboulch P, Chretien S, Tchertanov L, Baudin-Creuza V, Seigneuric R, Fontenay M, Garrido C, Hermine O, Courtois G.
| Oct 9, 2014
22.

Synergistic blockade of mitotic exit by two chemical inhibitors of the APC/C.

Nature.
Sackton KL, Dimova N, Zeng X, Tian W, Zhang M, Sackton TB, Meaders J, Pfaff KL, Sigoillot F, Yu H, Luo X, King RW.
| Oct 30, 2014
23.

Society: Don't blame the mothers.

Nature.
Richardson SS, Daniels CR, Gillman MW, Golden J, Kukla R, Kuzawa C, Rich-Edwards J.
| Aug 14, 2014
24.

CRISPR-mediated direct mutation of cancer genes in the mouse liver.

Nature.
Xue W, Chen S, Yin H, Tammela T, Papagiannakopoulos T, Joshi NS, Cai W, Yang G, Bronson R, Crowley DG, Zhang F, Anderson DG, Sharp PA, Jacks T.
| Oct 16, 2014
25.

PRC2 loss amplifies Ras-driven transcription and confers sensitivity to BRD4-based therapies.

Nature.
De Raedt T, Beert E, Pasmant E, Luscan A, Brems H, Ortonne N, Helin K, Hornick JL, Mautner V, Kehrer-Sawatzki H, Clapp W, Bradner J, Vidaud M, Upadhyaya M, Legius E, Cichowski K.
| Oct 9, 2014
26.

Inappropriate p53 activation during development induces features of CHARGE syndrome.

Nature.
Van Nostrand JL, Brady CA, Jung H, Fuentes DR, Kozak MM, Johnson TM, Lin CY, Lin CJ, Swiderski DL, Vogel H, Bernstein JA, Attié-Bitach T, Chang CP, Wysocka J, Martin DM, Attardi LD.
| Oct 9, 2014
27.

Enhanced neonatal Fc receptor function improves protection against primate SHIV infection.

Nature.
Ko SY, Pegu A, Rudicell RS, Yang ZY, Joyce MG, Chen X, Wang K, Bao S, Kraemer TD, Rath T, Zeng M, Schmidt SD, Todd JP, Penzak SR, Saunders KO, Nason MC, Haase AT, Rao SS, Blumberg RS, Mascola JR, Nabel GJ.
| Oct 30, 2014
28.

Oncogene ablation-resistant pancreatic cancer cells depend on mitochondrial function.

Nature.
Viale A, Pettazzoni P, Lyssiotis CA, Ying H, Sánchez N, Marchesini M, Carugo A, Green T, Seth S, Giuliani V, Kost-Alimova M, Muller F, Colla S, Nezi L, Genovese G, Deem AK, Kapoor A, Yao W, Brunetto E, Kang Y, Yuan M, Asara JM, Wang YA, Heffernan TP, Kimmelman AC, Wang H, Fleming JB, Cantley LC, DePinho RA, Draetta GF.
| Oct 30, 2014
29.

DNA methylation dynamics of the human preimplantation embryo.

Nature.
Smith ZD, Chan MM, Humm KC, Karnik R, Mekhoubad S, Regev A, Eggan K, Meissner A.
| Jul 31, 2014
30.

DNA-damage-induced differentiation of leukaemic cells as an anti-cancer barrier.

Nature.
Santos MA, Faryabi RB, Ergen AV, Day AM, Malhowski A, Canela A, Onozawa M, Lee JE, Callen E, Gutierrez-Martinez P, Chen HT, Wong N, Finkel N, Deshpande A, Sharrow S, Rossi DJ, Ito K, Ge K, Aplan PD, Armstrong SA, Nussenzweig A.
| Oct 2, 2014
31.

Tumour-derived PTH-related protein triggers adipose tissue browning and cancer cachexia.

Nature.
Kir S, White JP, Kleiner S, Kazak L, Cohen P, Baracos VE, Spiegelman BM.
| Sep 4, 2014
32.

Mutant IDH inhibits HNF-4α to block hepatocyte differentiation and promote biliary cancer.

Nature.
Saha SK, Parachoniak CA, Ghanta KS, Fitamant J, Ross KN, Najem MS, Gurumurthy S, Akbay EA, Sia D, Cornella H, Miltiadous O, Walesky C, Deshpande V, Zhu AX, Hezel AF, Yen KE, Straley KS, Travins J, Popovici-Muller J, Gliser C, Ferrone CR, Apte U, Llovet JM, Wong KK, Ramaswamy S, Bardeesy N.
| Sep 4, 2014
33.

Histone H4 tail mediates allosteric regulation of nucleosome remodelling by linker DNA.

Nature.
Hwang WL, Deindl S, Harada BT, Zhuang X.
| Aug 14, 2014
34.

Targeting transcription regulation in cancer with a covalent CDK7 inhibitor.

Nature.
Kwiatkowski N, Zhang T, Rahl PB, Abraham BJ, Reddy J, Ficarro SB, Dastur A, Amzallag A, Ramaswamy S, Tesar B, Jenkins CE, Hannett NM, McMillin D, Sanda T, Sim T, Kim ND, Look T, Mitsiades CS, Weng AP, Brown JR, Benes CH, Marto JA, Young RA, Gray NS.
| Jul 31, 2014
35.

Structure of the DDB1-CRBN E3 ubiquitin ligase in complex with thalidomide.

Nature.
Fischer ES, Böhm K, Lydeard JR, Yang H, Stadler MB, Cavadini S, Nagel J, Serluca F, Acker V, Lingaraju GM, Tichkule RB, Schebesta M, Forrester WC, Schirle M, Hassiepen U, Ottl J, Hild M, Beckwith RE, Harper JW, Jenkins JL, Thomä NH.
| Aug 7, 2014
36.

Loss of oncogenic Notch1 with resistance to a PI3K inhibitor in T-cell leukaemia.

Nature.
Dail M, Wong J, Lawrence J, O'Connor D, Nakitandwe J, Chen SC, Xu J, Lee LB, Akagi K, Li Q, Aster JC, Pear WS, Downing JR, Sampath D, Shannon K.
| Sep 25, 2014
37.

Rapid seeding of the viral reservoir prior to SIV viraemia in rhesus monkeys.

Nature.
Whitney JB, Hill AL, Sanisetty S, Penaloza-MacMaster P, Liu J, Shetty M, Parenteau L, Cabral C, Shields J, Blackmore S, Smith JY, Brinkman AL, Peter LE, Mathew SI, Smith KM, Borducchi EN, Rosenbloom DI, Lewis MG, Hattersley J, Li B, Hesselgesser J, Geleziunas R, Robb ML, Kim JH, Michael NL, Barouch DH.
| Aug 7, 2014
38.

ABCB5 is a limbal stem cell gene required for corneal development and repair.

Nature.
Ksander BR, Kolovou PE, Wilson BJ, Saab KR, Guo Q, Ma J, McGuire SP, Gregory MS, Vincent WJ, Perez VL, Cruz-Guilloty F, Kao WW, Call MK, Tucker BA, Zhan Q, Murphy GF, Lathrop KL, Alt C, Mortensen LJ, Lin CP, Zieske JD, Frank MH, Frank NY.
| Jul 17, 2014
39.

Patterning and post-patterning modes of evolutionary digit loss in mammals.

Nature.
Cooper KL, Sears KE, Uygur A, Maier J, Baczkowski KS, Brosnahan M, Antczak D, Skidmore JA, Tabin CJ.
| Jul 3, 2014
40.

Single-cell RNA-seq reveals dynamic paracrine control of cellular variation.

Nature.
Shalek AK, Satija R, Shuga J, Trombetta JJ, Gennert D, Lu D, Chen P, Gertner RS, Gaublomme JT, Yosef N, Schwartz S, Fowler B, Weaver S, Wang J, Wang X, Ding R, Raychowdhury R, Friedman N, Hacohen N, Park H, May AP, Regev A.
| Jun 19, 2014