Paper Chase is a research database designed to offer abstracts of research articles published in journals that have a highly rated impact factor as determined by ISI Impact Factor and PageRank. Abstracts are organized by date, with the most recently published papers listed first. 

Paper Chase

81.

A cell wall damage response mediated by a sensor kinase/response regulator pair enables beta-lactam tolerance.

Proc. Natl. Acad. Sci. U.S.A.
Dörr T, Alvarez L, Delgado F, Davis BM, Cava F, Waldor MK.
| Jan 12, 2016
82.

Ovarian cancer screening and mortality in the UK Collaborative Trial of Ovarian Cancer Screening (UKCTOCS): a randomised controlled trial.

Lancet.
Jacobs IJ, Menon U, Ryan A, Gentry-Maharaj A, Burnell M, Kalsi JK, Amso NN, Apostolidou S, Benjamin E, Cruickshank D, Crump DN, Davies SK, Dawnay A, Dobbs S, Fletcher G, Ford J, Godfrey K, Gunu R, Habib M, Hallett R, Herod J, Jenkins H, Karpinskyj C, Leeson S, Lewis SJ, Liston WR, Lopes A, Mould T, Murdoch J, Oram D, Rabideau DJ, Reynolds K, Scott I, Seif MW, Sharma A, Singh N, Taylor J, Warburton F, Widschwendter M, Williamson K, Woolas R, Fallowfield L, McGuire AJ, Campbell S, Parmar M, Skates SJ.
| Dec 17, 2015
83.

Everolimus for the treatment of advanced, non-functional neuroendocrine tumours of the lung or gastrointestinal tract (RADIANT-4): a randomised, placebo-controlled, phase 3 study.

Lancet.
Yao JC, Fazio N, Singh S, Buzzoni R, Carnaghi C, Wolin E, Tomasek J, Raderer M, Lahner H, Voi M, Pacaud LB, Rouyrre N, Sachs C, Valle JW, Fave GD, Van Cutsem E, Tesselaar M, Shimada Y, Oh DY, Strosberg J, Kulke MH, Pavel ME.
| Dec 15, 2015
84.

Insulator dysfunction and oncogene activation in IDH mutant gliomas.

Nature.
Flavahan WA, Drier Y, Liau BB, Gillespie SM, Venteicher AS, Stemmer-Rachamimov AO, Suvà ML, Bernstein BE.
| Jan 7, 2016
85.

Harnessing RNAi-based nanomedicines for therapeutic gene silencing in B-cell malignancies.

Proc. Natl. Acad. Sci. U.S.A.
Weinstein S, Toker IA, Emmanuel R, Ramishetti S, Hazan-Halevy I, Rosenblum D, Goldsmith M, Abraham A, Benjamini O, Bairey O, Raanani P, Nagler A, Lieberman J, Peer D.
| Jan 5, 2016
86.

APOL1 kidney disease risk variants cause cytotoxicity by depleting cellular potassium and inducing stress-activated protein kinases.

Proc. Natl. Acad. Sci. U.S.A.
Olabisi OA, Zhang JY, VerPlank L, Zahler N, DiBartolo S, Heneghan JF, Schlöndorff JS, Suh JH, Yan P, Alper SL, Friedman DJ, Pollak MR.
| Jan 26, 2016
87.

Nicastrin functions to sterically hinder γ-secretase-substrate interactions driven by substrate transmembrane domain.

Proc. Natl. Acad. Sci. U.S.A.
Bolduc DM, Montagna DR, Gu Y, Selkoe DJ, Wolfe MS.
| Feb 2, 2016
88.

High risk of near-crash driving events following night-shift work.

Proc. Natl. Acad. Sci. U.S.A.
Lee ML, Howard ME, Horrey WJ, Liang Y, Anderson C, Shreeve MS, O'Brien CS, Czeisler CA.
| Jan 5, 2016
89.

Mouse embryonic fibroblasts exhibit extensive developmental and phenotypic diversity.

Proc. Natl. Acad. Sci. U.S.A.
Singhal PK, Sassi S, Lan L, Au P, Halvorsen SC, Fukumura D, Jain RK, Seed B.
| Jan 5, 2016
90.

Selexipag for the Treatment of Pulmonary Arterial Hypertension.

N. Engl. J. Med.
Sitbon O, Channick R, Chin KM, Frey A, Gaine S, Galiè N, Ghofrani HA, Hoeper MM, Lang IM, Preiss R, Rubin LJ, Di Scala L, Tapson V, Adzerikho I, Liu J, Moiseeva O, Zeng X, Simonneau G, McLaughlin VV, Williams PG, Beghetti M, Corris P, Pepke-Zaba J, Souza R, DeMets DL, Gomberg-Maitland M, Greenberg BH, Schulman S, Douketis J, Amuchastegui M.
| Dec 24, 2015
91.

Resensitization to Crizotinib by the Lorlatinib ALK Resistance Mutation L1198F.

N. Engl. J. Med.
Shaw AT, Friboulet L, Leshchiner I, Gainor JF, Bergqvist S, Brooun A, Burke BJ, Deng YL, Liu W, Dardaei L, Frias RL, Schultz KR, Logan J, James LP, Smeal T, Timofeevski S, Katayama R, Iafrate AJ, Le L, McTigue M, Getz G, Johnson TW, Engelman JA.
| Jan 7, 2016
92.

Tau-driven 26S proteasome impairment and cognitive dysfunction can be prevented early in disease by activating cAMP-PKA signaling.

Nat. Med.
Myeku N, Clelland CL, Emrani S, Kukushkin NV, Yu WH, Goldberg AL, Duff KE.
| 12 21, 2015
93.

Genetic Identification of an Expansive Mechanoreceptor Sensitive to Skin Stroking.

Cell.
Bai L, Lehnert BP, Liu J, Neubarth NL, Dickendesher TL, Nwe PH, Cassidy C, Woodbury CJ, Ginty DD.
| Dec 17, 2015
94.

Not All Created Equal: Lineage Hard-Wiring in the Production of Blood.

Cell.
Mercier FE, Scadden DT.
| Dec 17, 2015
95.

Limiting Cholesterol Biosynthetic Flux Spontaneously Engages Type I IFN Signaling.

Cell.
York AG, Williams KJ, Argus JP, Zhou QD, Brar G, Vergnes L, Gray EE, Zhen A, Wu NC, Yamada DH, Cunningham CR, Tarling EJ, Wilks MQ, Casero D, Gray DH, Yu AK, Wang ES, Brooks DG, Sun R, Kitchen SG, Wu TT, Reue K, Stetson DB, Bensinger SJ.
| Dec 17, 2015
96.

ReEBOV Antigen Rapid Test kit for Ebola - Authors' reply.

Lancet.
Broadhurst MJ, Semper A, Bailey D, Pollock NR.
| Dec 5, 2015
97.

Autoinflammation and autoimmunity in systemic juvenile idiopathic arthritis.

Proc. Natl. Acad. Sci. U.S.A.
Nigrovic PA.
| Dec 29, 2015
98.

Hydroxycarbamide versus chronic transfusion for maintenance of transcranial doppler flow velocities in children with sickle cell anaemia-TCD With Transfusions Changing to Hydroxyurea (TWiTCH): a multicentre, open-label, phase 3, non-inferiority trial.

Lancet.
Ware RE, Davis BR, Schultz WH, Brown RC, Aygun B, Sarnaik S, Odame I, Fuh B, George A, Owen W, Luchtman-Jones L, Rogers ZR, Hilliard L, Gauger C, Piccone C, Lee MT, Kwiatkowski JL, Jackson S, Miller ST, Roberts C, Heeney MM, Kalfa TA, Nelson S, Imran H, Nottage K, Alvarez O, Rhodes M, Thompson AA, Rothman JA, Helton KJ, Roberts D, Coleman J, Bonner MJ, Kutlar A, Patel N, Wood J, Piller L, Wei P, Luden J, Mortier NA, Stuber SE, Luban NL, Cohen AR, Pressel S, Adams RJ.
| Dec 4, 2015
99.

cAMP-induced phosphorylation of 26S proteasomes on Rpn6/PSMD11 enhances their activity and the degradation of misfolded proteins.

Proc. Natl. Acad. Sci. U.S.A.
Lokireddy S, Kukushkin NV, Goldberg AL.
| Dec 29, 2015
100.

mTOR inhibition activates overall protein degradation by the ubiquitin proteasome system as well as by autophagy.

Proc. Natl. Acad. Sci. U.S.A.
Zhao J, Zhai B, Gygi SP, Goldberg AL.
| Dec 29, 2015