Paper Chase is a research database designed to offer abstracts of research articles published in journals that have a highly rated impact factor as determined by ISI Impact Factor and PageRank. Abstracts are organized by date, with the most recently published papers listed first. For a listing of HMS published papers from additional journals, visit Harvard Catalyst’s Medvane bibliome mining system.

Dopaminergic neurons inhibit striatal output through non-canonical release of GABA.

 

Squamous cell lung cancer (The Cancer Genome Atlas Research Network)

Challenging Parkinson’s dogma, dopamine may not be the only key player in this tragic neurodegenerative disease

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Critical role for lysyl oxidase in mesenchymal stem cell-driven breast cancer malignancy

 

Discovery reveals important clues to cancer metastasis. Findings offer a new direction in pursuit of potential therapies for bone metastasis.

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Paper Chase

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1.

Approval of a tuberculosis drug based on a paradoxical surrogate measure.

JAMA.
Avorn J.
| Apr 3, 2013
2.

Case records of the Massachusetts General Hospital. Case 3-2013. A 72-year-old woman with abdominal pain and distention after peritoneal dialysis.

N. Engl. J. Med.
Steele DJ, Kasmar AG, Guimaraes AR, Dekker JP.
| Jan 24, 2013
3.

Recognition of microbial and mammalian phospholipid antigens by NKT cells with diverse TCRs.

Proc. Natl. Acad. Sci. U.S.A.
Tatituri RV, Watts GF, Bhowruth V, Barton N, Rothchild A, Hsu FF, Almeida CF, Cox LR, Eggeling L, Cardell S, Rossjohn J, Godfrey DI, Behar SM, Besra GS, Brenner MB, Brigl M.
| Jan 29, 2013
4.

Tuberculosis, drug resistance, and the history of modern medicine.

N. Engl. J. Med.
Keshavjee S, Farmer PE.
| Sep 6, 2012
5.

Case records of the Massachusetts General Hospital. Case 5-2012. A 39-year-old man with a recent diagnosis of HIV infection and acute psychosis.

N. Engl. J. Med.
Freudenreich O, Basgoz N, Fernandez-Robles C, Larvie M, Misdraji J.
| Feb 16, 2012
6.

Lipidomic discovery of deoxysiderophores reveals a revised mycobactin biosynthesis pathway in Mycobacterium tuberculosis.

Proc. Natl. Acad. Sci. U.S.A.
Madigan CA, Cheng TY, Layre E, Young DC, McConnell MJ, Debono CA, Murry JP, Wei JR, Barry CE, Rodriguez GM, Matsunaga I, Rubin EJ, Moody DB.
| Jan 24, 2012
7.

Time for zero deaths from tuberculosis.

Lancet.
Keshavjee S, Harrington M, Gonsalves G, Chesire L, Farmer PE.
| Oct 22, 2011
8.

Case records of the Massachusetts General Hospital. Case 27-2011. A 17-year-old boy with abdominal pain and weight loss.

N. Engl. J. Med.
Winter HS, Gervais DA, Branda JA.
| Sep 8, 2011
9.

Tuberculosis burden in households of patients with multidrug-resistant and extensively drug-resistant tuberculosis: a retrospective cohort study.

Lancet.
Becerra MC, Appleton SC, Franke MF, Chalco K, Arteaga F, Bayona J, Murray M, Atwood SS, Mitnick CD.
| Jan 8, 2011
10.

Picking up the pace--scale-up of MDR tuberculosis treatment programs.

N. Engl. J. Med.
Keshavjee S, Farmer PE.
| Nov 4, 2010
11.

Time for a bold new vision at the Stop TB Partnership.

Lancet.
Keshavjee S, Girard F, Harrington M, Farmer PE.
| Oct 16, 2010
12.

Clinical problem-solving. Hard to conceive.

N. Engl. J. Med.
Levison JH, Barbieri RL, Katz JT, Loscalzo J.
| Sep 2, 2010
13.

Eicosanoid pathways regulate adaptive immunity to Mycobacterium tuberculosis.

Nat. Immunol.
Divangahi M, Desjardins D, Nunes-Alves C, Remold HG, Behar SM.
| 07 11, 2010
14.

Extensive phosphorylation with overlapping specificity by Mycobacterium tuberculosis serine/threonine protein kinases.

Proc. Natl. Acad. Sci. U.S.A.
Prisic S, Dankwa S, Schwartz D, Chou MF, Locasale JW, Kang CM, Bemis G, Church GM, Steen H, Husson RN.
| Apr 20, 2010
15.

Inhibition of bacterial disulfide bond formation by the anticoagulant warfarin.

Proc. Natl. Acad. Sci. U.S.A.
Dutton RJ, Wayman A, Wei JR, Rubin EJ, Beckwith J, Boyd D.
| Jan 5, 2010
16.

Antibiotics for emerging pathogens.

Science.
Fischbach MA, Walsh CT.
| Aug 28, 2009
17.

Mycobacterium tuberculosis evades macrophage defenses by inhibiting plasma membrane repair.

Nat. Immunol.
Divangahi M, Chen M, Gan H, Desjardins D, Hickman TT, Lee DM, Fortune S, Behar SM, Remold HG.
| 06 28, 2009
18.

Modeling the effects of strain diversity and mechanisms of strain competition on the potential performance of new tuberculosis vaccines.

Proc. Natl. Acad. Sci. U.S.A.
Cohen T, Colijn C, Murray M.
| Oct 21, 2008
19.

Mycobacterium tuberculosis blocks crosslinking of annexin-1 and apoptotic envelope formation on infected macrophages to maintain virulence.

Nat. Immunol.
Gan H, Lee J, Ren F, Chen M, Kornfeld H, Remold HG.
| 09 14, 2008
20.

Regulation of the SigH stress response regulon by an essential protein kinase in Mycobacterium tuberculosis.

Proc. Natl. Acad. Sci. U.S.A.
Park ST, Kang CM, Husson RN.
| Sep 2, 2008