Paper Chase is a research database designed to offer abstracts of research articles published in journals that have a highly rated impact factor as determined by ISI Impact Factor and PageRank. Abstracts are organized by date, with the most recently published papers listed first. 

Paper Chase

1.

Phosphoinositide 3-Kinase Regulates Glycolysis through Mobilization of Aldolase from the Actin Cytoskeleton.

Cell.
Hu H, Juvekar A, Lyssiotis CA, Lien EC, Albeck JG, Oh D, Varma G, Hung YP, Ullas S, Lauring J, Seth P, Lundquist MR, Tolan DR, Grant AK, Needleman DJ, Asara JM, Cantley LC, Wulf GM.
| Jan 28, 2016
2.

Control of proteasomal proteolysis by mTOR.

Nature.
Zhao J, Garcia GA, Goldberg AL.
| Jan 21, 2016
3.

mTOR inhibition activates overall protein degradation by the ubiquitin proteasome system as well as by autophagy.

Proc. Natl. Acad. Sci. U.S.A.
Zhao J, Zhai B, Gygi SP, Goldberg AL.
| Dec 29, 2015
4.

Melanoma Cell-Intrinsic PD-1 Receptor Functions Promote Tumor Growth.

Cell.
Kleffel S, Posch C, Barthel SR, Mueller H, Schlapbach C, Guenova E, Elco CP, Lee N, Juneja VR, Zhan Q, Lian CG, Thomi R, Hoetzenecker W, Cozzio A, Dummer R, Mihm MC, Flaherty KT, Frank MH, Murphy GF, Sharpe AH, Kupper TS, Schatton T.
| Sep 10, 2015
5.

Small-molecule enhancers of autophagy modulate cellular disease phenotypes suggested by human genetics.

Proc. Natl. Acad. Sci. U.S.A.
Kuo SY, Castoreno AB, Aldrich LN, Lassen KG, Goel G, Dančík V, Kuballa P, Latorre I, Conway KL, Sarkar S, Maetzel D, Jaenisch R, Clemons PA, Schreiber SL, Shamji AF, Xavier RJ.
| Aug 4, 2015
6.

The Circadian Protein BMAL1 Regulates Translation in Response to S6K1-Mediated Phosphorylation.

Cell.
Lipton JO, Yuan ED, Boyle LM, Ebrahimi-Fakhari D, Kwiatkowski E, Nathan A, Güttler T, Davis F, Asara JM, Sahin M.
| May 21, 2015
7.

Intracellular osteopontin regulates homeostasis and function of natural killer cells.

Proc. Natl. Acad. Sci. U.S.A.
Leavenworth JW, Verbinnen B, Wang Q, Shen E, Cantor H.
| Jan 13, 2015
8.

An in-tumor genetic screen reveals that the BET bromodomain protein, BRD4, is a potential therapeutic target in ovarian carcinoma.

Proc. Natl. Acad. Sci. U.S.A.
Baratta MG, Schinzel AC, Zwang Y, Bandopadhayay P, Bowman-Colin C, Kutt J, Curtis J, Piao H, Wong LC, Kung AL, Beroukhim R, Bradner JE, Drapkin R, Hahn WC, Liu JF, Livingston DM.
| Jan 6, 2015
9.

Genetic modifiers of EGFR dependence in non-small cell lung cancer.

Proc. Natl. Acad. Sci. U.S.A.
Sharifnia T, Rusu V, Piccioni F, Bagul M, Imielinski M, Cherniack AD, Pedamallu CS, Wong B, Wilson FH, Garraway LA, Altshuler D, Golub TR, Root DE, Subramanian A, Meyerson M.
| Dec 30, 2014
10.

Complementary genomic approaches highlight the PI3K/mTOR pathway as a common vulnerability in osteosarcoma.

Proc. Natl. Acad. Sci. U.S.A.
Perry JA, Kiezun A, Tonzi P, Van Allen EM, Carter SL, Baca SC, Cowley GS, Bhatt AS, Rheinbay E, Pedamallu CS, Helman E, Taylor-Weiner A, McKenna A, DeLuca DS, Lawrence MS, Ambrogio L, Sougnez C, Sivachenko A, Walensky LD, Wagle N, Mora J, de Torres C, Lavarino C, Dos Santos Aguiar S, Yunes JA, Brandalise SR, Mercado-Celis GE, Melendez-Zajgla J, Cárdenas-Cardós R, Velasco-Hidalgo L, Roberts CW, Garraway LA, Rodriguez-Galindo C, Gabriel SB, Lander ES, Golub TR, Orkin SH, Getz G, Janeway KA.
| Dec 23, 2014
11.

Mutations in G protein β subunits promote transformation and kinase inhibitor resistance.

Nat. Med.
Yoda A, Adelmant G, Tamburini J, Chapuy B, Shindoh N, Yoda Y, Weigert O, Kopp N, Wu SC, Kim SS, Liu H, Tivey T, Christie AL, Elpek KG, Card J, Gritsman K, Gotlib J, Deininger MW, Makishima H, Turley SJ, Javidi-Sharifi N, Maciejewski JP, Jaiswal S, Ebert BL, Rodig SJ, Tyner JW, Marto JA, Weinstock DM, Lane AA.
| 12 08, 2014
12.

G protein-coupled receptor 56 regulates mechanical overload-induced muscle hypertrophy.

Proc. Natl. Acad. Sci. U.S.A.
White JP, Wrann CD, Rao RR, Nair SK, Jedrychowski MP, You JS, Martínez-Redondo V, Gygi SP, Ruas JL, Hornberger TA, Wu Z, Glass DJ, Piao X, Spiegelman BM.
| Nov 4, 2014
13.

Response and acquired resistance to everolimus in anaplastic thyroid cancer.

N. Engl. J. Med.
Wagle N, Grabiner BC, Van Allen EM, Amin-Mansour A, Taylor-Weiner A, Rosenberg M, Gray N, Barletta JA, Guo Y, Swanson SJ, Ruan DT, Hanna GJ, Haddad RI, Getz G, Kwiatkowski DJ, Carter SL, Sabatini DM, Jänne PA, Garraway LA, Lorch JH.
| Oct 9, 2014
14.

mTOR- and HIF-1α-mediated aerobic glycolysis as metabolic basis for trained immunity.

Science.
Cheng SC, Quintin J, Cramer RA, Shepardson KM, Saeed S, Kumar V, Giamarellos-Bourboulis EJ, Martens JH, Rao NA, Aghajanirefah A, Manjeri GR, Li Y, Ifrim DC, Arts RJ, van der Veer BM, van der Meer BM, Deen PM, Logie C, O'Neill LA, Willems P, van de Veerdonk FL, van der Meer JW, Ng A, Joosten LA, Wijmenga C, Stunnenberg HG, Xavier RJ, Netea MG.
| Sep 26, 2014
15.

Medicine. A common pathway for a rare disease?

Science.
Vafai SB, Mootha VK.
| Dec 20, 2013
16.

Phenformin enhances the therapeutic benefit of BRAF(V600E) inhibition in melanoma.

Proc. Natl. Acad. Sci. U.S.A.
Yuan P, Ito K, Perez-Lorenzo R, Del Guzzo C, Lee JH, Shen CH, Bosenberg MW, McMahon M, Cantley LC, Zheng B.
| Nov 5, 2013
17.

Integration of mTOR and estrogen-ERK2 signaling in lymphangioleiomyomatosis pathogenesis.

Proc. Natl. Acad. Sci. U.S.A.
Gu X, Yu JJ, Ilter D, Blenis N, Henske EP, Blenis J.
| Sep 10, 2013
18.

Multiple risk pathways for schizophrenia converge in serine racemase knockout mice, a mouse model of NMDA receptor hypofunction.

Proc. Natl. Acad. Sci. U.S.A.
Balu DT, Li Y, Puhl MD, Benneyworth MA, Basu AC, Takagi S, Bolshakov VY, Coyle JT.
| Jun 25, 2013
19.

Learning and reconsolidation implicate different synaptic mechanisms.

Proc. Natl. Acad. Sci. U.S.A.
Li Y, Meloni EG, Carlezon WA, Milad MR, Pitman RK, Nader K, Bolshakov VY.
| Mar 19, 2013