Paper Chase is a research database designed to offer abstracts of research articles published in journals that have a highly rated impact factor as determined by ISI Impact Factor and PageRank. Abstracts are organized by date, with the most recently published papers listed first. 

Paper Chase

1.

Genetic modifiers of EGFR dependence in non-small cell lung cancer.

Proc. Natl. Acad. Sci. U.S.A.
Sharifnia T, Rusu V, Piccioni F, Bagul M, Imielinski M, Cherniack AD, Pedamallu CS, Wong B, Wilson FH, Garraway LA, Altshuler D, Golub TR, Root DE, Subramanian A, Meyerson M.
| Dec 15, 2014
2.

Complementary genomic approaches highlight the PI3K/mTOR pathway as a common vulnerability in osteosarcoma.

Proc. Natl. Acad. Sci. U.S.A.
Perry JA, Kiezun A, Tonzi P, Van Allen EM, Carter SL, Baca SC, Cowley GS, Bhatt AS, Rheinbay E, Pedamallu CS, Helman E, Taylor-Weiner A, McKenna A, DeLuca DS, Lawrence MS, Ambrogio L, Sougnez C, Sivachenko A, Walensky LD, Wagle N, Mora J, de Torres C, Lavarino C, Dos Santos Aguiar S, Yunes JA, Brandalise SR, Mercado-Celis GE, Melendez-Zajgla J, Cárdenas-Cardós R, Velasco-Hidalgo L, Roberts CW, Garraway LA, Rodriguez-Galindo C, Gabriel SB, Lander ES, Golub TR, Orkin SH, Getz G, Janeway KA.
| Dec 15, 2014
3.

Mutations in G protein β subunits promote transformation and kinase inhibitor resistance.

Nat. Med.
Yoda A, Adelmant G, Tamburini J, Chapuy B, Shindoh N, Yoda Y, Weigert O, Kopp N, Wu SC, Kim SS, Liu H, Tivey T, Christie AL, Elpek KG, Card J, Gritsman K, Gotlib J, Deininger MW, Makishima H, Turley SJ, Javidi-Sharifi N, Maciejewski JP, Jaiswal S, Ebert BL, Rodig SJ, Tyner JW, Marto JA, Weinstock DM, Lane AA.
| Dec 8, 2014
4.

G protein-coupled receptor 56 regulates mechanical overload-induced muscle hypertrophy.

Proc. Natl. Acad. Sci. U.S.A.
White JP, Wrann CD, Rao RR, Nair SK, Jedrychowski MP, You JS, Martínez-Redondo V, Gygi SP, Ruas JL, Hornberger TA, Wu Z, Glass DJ, Piao X, Spiegelman BM.
| Nov 4, 2014
5.

Response and acquired resistance to everolimus in anaplastic thyroid cancer.

N. Engl. J. Med.
Wagle N, Grabiner BC, Van Allen EM, Amin-Mansour A, Taylor-Weiner A, Rosenberg M, Gray N, Barletta JA, Guo Y, Swanson SJ, Ruan DT, Hanna GJ, Haddad RI, Getz G, Kwiatkowski DJ, Carter SL, Sabatini DM, Jänne PA, Garraway LA, Lorch JH.
| Oct 9, 2014
6.

mTOR- and HIF-1α-mediated aerobic glycolysis as metabolic basis for trained immunity.

Science.
Cheng SC, Quintin J, Cramer RA, Shepardson KM, Saeed S, Kumar V, Giamarellos-Bourboulis EJ, Martens JH, Rao NA, Aghajanirefah A, Manjeri GR, Li Y, Ifrim DC, Arts RJ, van der Veer BM, van der Meer BM, Deen PM, Logie C, O'Neill LA, Willems P, van de Veerdonk FL, van der Meer JW, Ng A, Joosten LA, Wijmenga C, Stunnenberg HG, Xavier RJ, Netea MG.
| Sep 26, 2014
7.

Medicine. A common pathway for a rare disease?

Science.
Vafai SB, Mootha VK.
| Dec 20, 2013
8.

Phenformin enhances the therapeutic benefit of BRAF(V600E) inhibition in melanoma.

Proc. Natl. Acad. Sci. U.S.A.
Yuan P, Ito K, Perez-Lorenzo R, Del Guzzo C, Lee JH, Shen CH, Bosenberg MW, McMahon M, Cantley LC, Zheng B.
| Nov 5, 2013
9.

Integration of mTOR and estrogen-ERK2 signaling in lymphangioleiomyomatosis pathogenesis.

Proc. Natl. Acad. Sci. U.S.A.
Gu X, Yu JJ, Ilter D, Blenis N, Henske EP, Blenis J.
| Sep 10, 2013
10.

Multiple risk pathways for schizophrenia converge in serine racemase knockout mice, a mouse model of NMDA receptor hypofunction.

Proc. Natl. Acad. Sci. U.S.A.
Balu DT, Li Y, Puhl MD, Benneyworth MA, Basu AC, Takagi S, Bolshakov VY, Coyle JT.
| Jun 25, 2013
11.

Learning and reconsolidation implicate different synaptic mechanisms.

Proc. Natl. Acad. Sci. U.S.A.
Li Y, Meloni EG, Carlezon WA, Milad MR, Pitman RK, Nader K, Bolshakov VY.
| Mar 19, 2013
13.

No REST for fibroids.

Proc. Natl. Acad. Sci. U.S.A.
Rueda BR, Davis JS.
| Feb 5, 2013
14.

Autistic-like behaviour and cerebellar dysfunction in Purkinje cell Tsc1 mutant mice.

Nature.
Tsai PT, Hull C, Chu Y, Greene-Colozzi E, Sadowski AR, Leech JM, Steinberg J, Crawley JN, Regehr WG, Sahin M.
| Aug 30, 2012
15.

A unifying model for mTORC1-mediated regulation of mRNA translation.

Nature.
Thoreen CC, Chantranupong L, Keys HR, Wang T, Gray NS, Sabatini DM.
| May 3, 2012
16.

Nuclear receptor Nr4a1 modulates both regulatory T-cell (Treg) differentiation and clonal deletion.

Proc. Natl. Acad. Sci. U.S.A.
Fassett MS, Jiang W, D'Alise AM, Mathis D, Benoist C.
| Mar 6, 2012
17.

Everolimus in postmenopausal hormone-receptor-positive advanced breast cancer.

N. Engl. J. Med.
Baselga J, Campone M, Piccart M, Burris HA, Rugo HS, Sahmoud T, Noguchi S, Gnant M, Pritchard KI, Lebrun F, Beck JT, Ito Y, Yardley D, Deleu I, Perez A, Bachelot T, Vittori L, Xu Z, Mukhopadhyay P, Lebwohl D, Hortobagyi GN.
| Feb 9, 2012
18.

Sustained axon regeneration induced by co-deletion of PTEN and SOCS3.

Nature.
Sun F, Park KK, Belin S, Wang D, Lu T, Chen G, Zhang K, Yeung C, Feng G, Yankner BA, He Z.
| Dec 15, 2011
19.

Regulable neural progenitor-specific Tsc1 loss yields giant cells with organellar dysfunction in a model of tuberous sclerosis complex.

Proc. Natl. Acad. Sci. U.S.A.
Goto J, Talos DM, Klein P, Qin W, Chekaluk YI, Anderl S, Malinowska IA, Di Nardo A, Bronson RT, Chan JA, Vinters HV, Kernie SG, Jensen FE, Sahin M, Kwiatkowski DJ.
| Nov 8, 2011
20.

The Lin28/let-7 axis regulates glucose metabolism.

Cell.
Zhu H, Shyh-Chang N, Segrè AV, Shinoda G, Shah SP, Einhorn WS, Takeuchi A, Engreitz JM, Hagan JP, Kharas MG, Urbach A, Thornton JE, Triboulet R, Gregory RI, Altshuler D, Daley GQ.
| Sep 30, 2011