Paper Chase is a research database designed to offer abstracts of research articles published in journals that have a highly rated impact factor as determined by ISI Impact Factor and PageRank. Abstracts are organized by date, with the most recently published papers listed first. For a listing of HMS published papers from additional journals, visit Harvard Catalyst’s Medvane bibliome mining system.

Dopaminergic neurons inhibit striatal output through non-canonical release of GABA.

 

Squamous cell lung cancer (The Cancer Genome Atlas Research Network)

Challenging Parkinson’s dogma, dopamine may not be the only key player in this tragic neurodegenerative disease

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Critical role for lysyl oxidase in mesenchymal stem cell-driven breast cancer malignancy

 

Discovery reveals important clues to cancer metastasis. Findings offer a new direction in pursuit of potential therapies for bone metastasis.

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Paper Chase

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1.

Evolution and impact of subclonal mutations in chronic lymphocytic leukemia.

Cell.
Landau DA, Carter SL, Stojanov P, McKenna A, Stevenson K, Lawrence MS, Sougnez C, Stewart C, Sivachenko A, Wang L, Wan Y, Zhang W, Shukla SA, Vartanov A, Fernandes SM, Saksena G, Cibulskis K, Tesar B, Gabriel S, Hacohen N, Meyerson M, Lander ES, Neuberg D, Brown JR, Getz G, Wu CJ.
| Feb 14, 2013
2.

Microcephaly gene links trithorax and REST/NRSF to control neural stem cell proliferation and differentiation.

Cell.
Yang YJ, Baltus AE, Mathew RS, Murphy EA, Evrony GD, Gonzalez DM, Wang EP, Marshall-Walker CA, Barry BJ, Murn J, Tatarakis A, Mahajan MA, Samuels HH, Shi Y, Golden JA, Mahajnah M, Shenhav R, Walsh CA.
| Nov 21, 2012
3.

Case records of the Massachusetts General Hospital. Case 24-2012. A 38-year-old man with abdominal pain and altered mental status.

N. Engl. J. Med.
Fathi AT, Chen YB, Carter BW, Ryan RJ.
| Aug 9, 2012
4.

A piece of my mind. To Isaiah.

JAMA.
Berwick DM.
| Jun 27, 2012
5.

SF3B1 and other novel cancer genes in chronic lymphocytic leukemia.

N. Engl. J. Med.
Wang L, Lawrence MS, Wan Y, Stojanov P, Sougnez C, Stevenson K, Werner L, Sivachenko A, DeLuca DS, Zhang L, Zhang W, Vartanov AR, Fernandes SM, Goldstein NR, Folco EG, Cibulskis K, Tesar B, Sievers QL, Shefler E, Gabriel S, Hacohen N, Reed R, Meyerson M, Golub TR, Lander ES, Neuberg D, Brown JR, Getz G, Wu CJ.
| Dec 29, 2011
6.

Pretreatment mitochondrial priming correlates with clinical response to cytotoxic chemotherapy.

Science.
Ni Chonghaile T, Sarosiek KA, Vo TT, Ryan JA, Tammareddi A, Moore Vdel G, Deng J, Anderson KC, Richardson P, Tai YT, Mitsiades CS, Matulonis UA, Drapkin R, Stone R, Deangelo DJ, McConkey DJ, Sallan SE, Silverman L, Hirsch MS, Carrasco DR, Letai A.
| Nov 25, 2011
7.

Clinical practice. Adult primary care after childhood acute lymphoblastic leukemia.

N. Engl. J. Med.
Diller L.
| Oct 13, 2011
8.

Genome-wide analysis reveals conserved and divergent features of Notch1/RBPJ binding in human and murine T-lymphoblastic leukemia cells.

Proc. Natl. Acad. Sci. U.S.A.
Wang H, Zou J, Zhao B, Johannsen E, Ashworth T, Wong H, Pear WS, Schug J, Blacklow SC, Arnett KL, Bernstein BE, Kieff E, Aster JC.
| Sep 6, 2011
9.

SCF(FBW7) regulates cellular apoptosis by targeting MCL1 for ubiquitylation and destruction.

Nature.
Inuzuka H, Shaik S, Onoyama I, Gao D, Tseng A, Maser RS, Zhai B, Wan L, Gutierrez A, Lau AW, Xiao Y, Christie AL, Aster J, Settleman J, Gygi SP, Kung AL, Look T, Nakayama KI, DePinho RA, Wei W.
| Mar 3, 2011
10.

Case records of the Massachusetts General Hospital. Case 4-2011. A 4-year-old boy with back pain and hypercalcemia.

N. Engl. J. Med.
El Saleeby CM, Grottkau BE, Friedmann AM, Westra SJ, Sohani AR.
| Feb 10, 2011
11.

T-cell receptor-driven lymphomagenesis in mice derived from a reprogrammed T cell.

Proc. Natl. Acad. Sci. U.S.A.
Serwold T, Hochedlinger K, Swindle J, Hedgpeth J, Jaenisch R, Weissman IL.
| Nov 2, 2010
12.

Functional screening identifies CRLF2 in precursor B-cell acute lymphoblastic leukemia.

Proc. Natl. Acad. Sci. U.S.A.
Yoda A, Yoda Y, Chiaretti S, Bar-Natan M, Mani K, Rodig SJ, West N, Xiao Y, Brown JR, Mitsiades C, Sattler M, Kutok JL, DeAngelo DJ, Wadleigh M, Piciocchi A, Dal Cin P, Bradner JE, Griffin JD, Anderson KC, Stone RM, Ritz J, Foà R, Aster JC, Frank DA, Weinstock DM.
| Jan 5, 2010
13.

E(mu)-TCL1 mice represent a model for immunotherapeutic reversal of chronic lymphocytic leukemia-induced T-cell dysfunction.

Proc. Natl. Acad. Sci. U.S.A.
Gorgun G, Ramsay AG, Holderried TA, Zahrieh D, Le Dieu R, Liu F, Quackenbush J, Croce CM, Gribben JG.
| Apr 14, 2009
14.

Chromosomally unstable mouse tumours have genomic alterations similar to diverse human cancers.

Nature.
Maser RS, Choudhury B, Campbell PJ, Feng B, Wong KK, Protopopov A, O'Neil J, Gutierrez A, Ivanova E, Perna I, Lin E, Mani V, Jiang S, McNamara K, Zaghlul S, Edkins S, Stevens C, Brennan C, Martin ES, Wiedemeyer R, Kabbarah O, Nogueira C, Histen G, Aster J, Mansour M, Duke V, Foroni L, Fielding AK, Goldstone AH, Rowe JM, Wang YA, Look AT, Stratton MR, Chin L, Futreal PA, DePinho RA.
| Jun 21, 2007
15.

Case records of the Massachusetts General Hospital. Case 40-2006. A 64-year-old man with anemia and a low level of HDL cholesterol.

N. Engl. J. Med.
Murali MR, Kratz A, Finberg KE.
| Dec 28, 2006
16.

Analysis of gene expression in pathophysiological states: balancing false discovery and false negative rates.

Proc. Natl. Acad. Sci. U.S.A.
Norris AW, Kahn CR.
| Jan 17, 2006
17.

In vivo imaging of specialized bone marrow endothelial microdomains for tumour engraftment.

Nature.
Sipkins DA, Wei X, Wu JW, Runnels JM, Côté D, Means TK, Luster AD, Scadden DT, Lin CP.
| Jun 16, 2005
18.

Cre/lox-regulated transgenic zebrafish model with conditional myc-induced T cell acute lymphoblastic leukemia.

Proc. Natl. Acad. Sci. U.S.A.
Langenau DM, Feng H, Berghmans S, Kanki JP, Kutok JL, Look AT.
| Apr 26, 2005
19.

Activating mutations of NOTCH1 in human T cell acute lymphoblastic leukemia.

Science.
Weng AP, Ferrando AA, Lee W, Morris JP, Silverman LB, Sanchez-Irizarry C, Blacklow SC, Look AT, Aster JC.
| Oct 8, 2004
20.

Case records of the Massachusetts General Hospital. Weekly clinicopathological exercises. Case 15-2004. A 31-year-old man with bilateral testicular enlargement.

N. Engl. J. Med.
Ballen KK, Hasserjian RP.
| May 13, 2004