Paper Chase is a research database designed to offer abstracts of research articles published in journals that have a highly rated impact factor as determined by ISI Impact Factor and PageRank. Abstracts are organized by date, with the most recently published papers listed first. For a listing of HMS published papers from additional journals, visit Harvard Catalyst’s Medvane bibliome mining system.

Dopaminergic neurons inhibit striatal output through non-canonical release of GABA.

 

Squamous cell lung cancer (The Cancer Genome Atlas Research Network)

Challenging Parkinson’s dogma, dopamine may not be the only key player in this tragic neurodegenerative disease

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Critical role for lysyl oxidase in mesenchymal stem cell-driven breast cancer malignancy

 

Discovery reveals important clues to cancer metastasis. Findings offer a new direction in pursuit of potential therapies for bone metastasis.

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Paper Chase

2.

A function for cyclin D1 in DNA repair uncovered by protein interactome analyses in human cancers.

Nature.
Jirawatnotai S, Hu Y, Michowski W, Elias JE, Becks L, Bienvenu F, Zagozdzon A, Goswami T, Wang YE, Clark AB, Kunkel TA, van Harn T, Xia B, Correll M, Quackenbush J, Livingston DM, Gygi SP, Sicinski P.
| Jun 9, 2011
3.

SMAD4-dependent barrier constrains prostate cancer growth and metastatic progression.

Nature.
Ding Z, Wu CJ, Chu GC, Xiao Y, Ho D, Zhang J, Perry SR, Labrot ES, Wu X, Lis R, Hoshida Y, Hiller D, Hu B, Jiang S, Zheng H, Stegh AH, Scott KL, Signoretti S, Bardeesy N, Wang YA, Hill DE, Golub TR, Stampfer MJ, Wong WH, Loda M, Mucci L, Chin L, DePinho RA.
| Feb 10, 2011
4.

Transcriptional role of cyclin D1 in development revealed by a genetic-proteomic screen.

Nature.
Bienvenu F, Jirawatnotai S, Elias JE, Meyer CA, Mizeracka K, Marson A, Frampton GM, Cole MF, Odom DT, Odajima J, Geng Y, Zagozdzon A, Jecrois M, Young RA, Liu XS, Cepko CL, Gygi SP, Sicinski P.
| Jan 21, 2010
5.

Systemic leukocyte-directed siRNA delivery revealing cyclin D1 as an anti-inflammatory target.

Science.
Peer D, Park EJ, Morishita Y, Carman CV, Shimaoka M.
| Feb 1, 2008
6.

Sonic hedgehog-induced type 3 deiodinase blocks thyroid hormone action enhancing proliferation of normal and malignant keratinocytes.

Proc. Natl. Acad. Sci. U.S.A.
Dentice M, Luongo C, Huang S, Ambrosio R, Elefante A, Mirebeau-Prunier D, Zavacki AM, Fenzi G, Grachtchouk M, Hutchin M, Dlugosz AA, Bianco AC, Missero C, Larsen PR, Salvatore D.
| Sep 4, 2007
7.

Mouse development and cell proliferation in the absence of D-cyclins.

Cell.
Kozar K, Ciemerych MA, Rebel VI, Shigematsu H, Zagozdzon A, Sicinska E, Geng Y, Yu Q, Bhattacharya S, Bronson RT, Akashi K, Sicinski P.
| Aug 20, 2004
8.

A mechanism of cyclin D1 action encoded in the patterns of gene expression in human cancer.

Cell.
Lamb J, Ramaswamy S, Ford HL, Contreras B, Martinez RV, Kittrell FS, Zahnow CA, Patterson N, Golub TR, Ewen ME.
| Aug 8, 2003
9.

The role of apoptosis in creating and maintaining luminal space within normal and oncogene-expressing mammary acini.

Cell.
Debnath J, Mills KR, Collins NL, Reginato MJ, Muthuswamy SK, Brugge JS.
| Oct 4, 2002
10.

Loss of Pin1 function in the mouse causes phenotypes resembling cyclin D1-null phenotypes.

Proc. Natl. Acad. Sci. U.S.A.
Liou YC, Ryo A, Huang HK, Lu PJ, Bronson R, Fujimori F, Uchida T, Hunter T, Lu KP.
| Feb 5, 2002
11.

The nuclear factor kappa B (NF-kappa B): a potential therapeutic target for estrogen receptor negative breast cancers.

Proc. Natl. Acad. Sci. U.S.A.
Biswas DK, Dai SC, Cruz A, Weiser B, Graner E, Pardee AB.
| Aug 28, 2001
12.

Specific protection against breast cancers by cyclin D1 ablation.

Nature.
Yu Q, Geng Y, Sicinski P.
| Jun 28, 2001
13.

Deletion of the p27Kip1 gene restores normal development in cyclin D1-deficient mice.

Proc. Natl. Acad. Sci. U.S.A.
Geng Y, Yu Q, Sicinska E, Das M, Bronson RT, Sicinski P.
| Jan 2, 2001
15.

Rescue of cyclin D1 deficiency by knockin cyclin E.

Cell.
Geng Y, Whoriskey W, Park MY, Bronson RT, Medema RH, Li T, Weinberg RA, Sicinski P.
| Jun 11, 1999
16.

P/CAF associates with cyclin D1 and potentiates its activation of the estrogen receptor.

Proc. Natl. Acad. Sci. U.S.A.
McMahon C, Suthiphongchai T, DiRenzo J, Ewen ME.
| May 11, 1999
17.

The cyclin-dependent kinase inhibitor p27(Kip1) induces N-terminal proteolytic cleavage of cyclin A.

Proc. Natl. Acad. Sci. U.S.A.
Bastians H, Townsley FM, Ruderman JV.
| Dec 22, 1998
18.

A unique pattern of photoreceptor degeneration in cyclin D1 mutant mice.

Proc. Natl. Acad. Sci. U.S.A.
Ma C, Papermaster D, Cepko CL.
| Aug 18, 1998
19.

Depletion of intracellular Ca2+ stores, phosphorylation of eIF2alpha, and sustained inhibition of translation initiation mediate the anticancer effects of clotrimazole.

Proc. Natl. Acad. Sci. U.S.A.
Aktas H, Flückiger R, Acosta JA, Savage JM, Palakurthi SS, Halperin JA.
| Jul 7, 1998
20.

Tumor-selective transgene expression in vivo mediated by an E2F-responsive adenoviral vector.

Nat. Med.
Parr MJ, Manome Y, Tanaka T, Wen P, Kufe DW, Kaelin WG, Fine HA.
| 10 23, 1997