Paper Chase is a research database designed to offer abstracts of research articles published in journals that have a highly rated impact factor as determined by ISI Impact Factor and PageRank. Abstracts are organized by date, with the most recently published papers listed first. 

Paper Chase

1.

GLTSCR2/PICT1 links mitochondrial stress and Myc signaling.

Proc. Natl. Acad. Sci. U.S.A.
Yoon JC, Ling AJ, Isik M, Lee DY, Steinbaugh MJ, Sack LM, Boduch AN, Blackwell TK, Sinclair DA, Elledge SJ.
| Mar 11, 2014
2.

Declining NAD(+) induces a pseudohypoxic state disrupting nuclear-mitochondrial communication during aging.

Cell.
Gomes AP, Price NL, Ling AJ, Moslehi JJ, Montgomery MK, Rajman L, White JP, Teodoro JS, Wrann CD, Hubbard BP, Mercken EM, Palmeira CM, de Cabo R, Rolo AP, Turner N, Bell EL, Sinclair DA.
| Dec 19, 2013
3.

Evidence for a common mechanism of SIRT1 regulation by allosteric activators.

Science.
Hubbard BP, Gomes AP, Dai H, Li J, Case AW, Considine T, Riera TV, Lee JE, E SY, Lamming DW, Pentelute BL, Schuman ER, Stevens LA, Ling AJ, Armour SM, Michan S, Zhao H, Jiang Y, Sweitzer SM, Blum CA, Disch JS, Ng PY, Howitz KT, Rolo AP, Hamuro Y, Moss J, Perni RB, Ellis JL, Vlasuk GP, Sinclair DA.
| Mar 8, 2013
4.

SIRT1 redistribution on chromatin promotes genomic stability but alters gene expression during aging.

Cell.
Oberdoerffer P, Michan S, McVay M, Mostoslavsky R, Vann J, Park SK, Hartlerode A, Stegmuller J, Hafner A, Loerch P, Wright SM, Mills KD, Bonni A, Yankner BA, Scully R, Prolla TA, Alt FW, Sinclair DA.
| Nov 28, 2008
5.

Nutrient-sensitive mitochondrial NAD+ levels dictate cell survival.

Cell.
Yang H, Yang T, Baur JA, Perez E, Matsui T, Carmona JJ, Lamming DW, Souza-Pinto NC, Bohr VA, Rosenzweig A, de Cabo R, Sauve AA, Sinclair DA.
| Sep 21, 2007
6.

Resveratrol improves health and survival of mice on a high-calorie diet.

Nature.
Baur JA, Pearson KJ, Price NL, Jamieson HA, Lerin C, Kalra A, Prabhu VV, Allard JS, Lopez-Lluch G, Lewis K, Pistell PJ, Poosala S, Becker KG, Boss O, Gwinn D, Wang M, Ramaswamy S, Fishbein KW, Spencer RG, Lakatta EG, Le Couteur D, Shaw RJ, Navas P, Puigserver P, Ingram DK, de Cabo R, Sinclair DA.
| Nov 16, 2006
7.

HST2 mediates SIR2-independent life-span extension by calorie restriction.

Science.
Lamming DW, Latorre-Esteves M, Medvedik O, Wong SN, Tsang FA, Wang C, Lin SJ, Sinclair DA.
| Sep 16, 2005
8.

Sirtuin activators mimic caloric restriction and delay ageing in metazoans.

Nature.
Wood JG, Rogina B, Lavu S, Howitz K, Helfand SL, Tatar M, Sinclair D.
| Aug 5, 2004
9.

Calorie restriction promotes mammalian cell survival by inducing the SIRT1 deacetylase.

Science.
Cohen HY, Miller C, Bitterman KJ, Wall NR, Hekking B, Kessler B, Howitz KT, Gorospe M, de Cabo R, Sinclair DA.
| Jul 16, 2004
10.

Stress-dependent regulation of FOXO transcription factors by the SIRT1 deacetylase.

Science.
Brunet A, Sweeney LB, Sturgill JF, Chua KF, Greer PL, Lin Y, Tran H, Ross SE, Mostoslavsky R, Cohen HY, Hu LS, Cheng HL, Jedrychowski MP, Gygi SP, Sinclair DA, Alt FW, Greenberg ME.
| Mar 26, 2004
11.

Yeast life-span extension by calorie restriction is independent of NAD fluctuation.

Science.
Anderson RM, Latorre-Esteves M, Neves AR, Lavu S, Medvedik O, Taylor C, Howitz KT, Santos H, Sinclair DA.
| Dec 19, 2003
12.

Cell biology. An age of instability.

Science.
Sinclair DA.
| Sep 26, 2003
13.

Nicotinamide and PNC1 govern lifespan extension by calorie restriction in Saccharomyces cerevisiae.

Nature.
Anderson RM, Bitterman KJ, Wood JG, Medvedik O, Sinclair DA.
| May 8, 2003
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