Paper Chase is a research database designed to offer abstracts of research articles published in journals that have a highly rated impact factor as determined by ISI Impact Factor and PageRank. Abstracts are organized by date, with the most recently published papers listed first. 

Paper Chase

Merkel cells are a touchy subject.

Cell. Apr 24, 2014;157(3):531-3.
Ma Q.

Dana-Farber Cancer Institute and Department of Neurobiology, Harvard Medical School, 450 Brookline Street, Boston, MA 02115, USA. Electronic address: qiufu_ma@dfci.harvard.edu.

Abstract:

How the Merkel cell-neurite complex transduces and encodes touch remains unclear. Ikeda et al. now implicate Merkel cells as the primary sites of tactile transduction and the ion channel Piezo2 as the chief mechanotransducer. Surprisingly, Merkel cells also mediate allodynia, providing a new cellular target for chronic pain treatment.