Paper Chase is a research database designed to offer abstracts of research articles published in journals that have a highly rated impact factor as determined by ISI Impact Factor and PageRank. Abstracts are organized by date, with the most recently published papers listed first.
Ephs and ephrins keep pancreatic Beta cells connected.
Cell.Apr 20, 2007;129(2):241-3.
Kulkarni RN, Kahn CR.
Division of Cell and Molecular Physiology, Joslin Diabetes Center, Department of Medicine, Harvard Medical School, Boston MA 02215, USA. firstname.lastname@example.org
How insulin-secreting beta cells of the pancreas communicate with each other is largely unknown. In this issue of Cell, Konstantinova et al. (2007) show that the signaling proteins EphA and ephrin-A modulate insulin secretion, providing fresh insights into the functional significance of the clustering of beta cells, which occurs in islets.